author consortium pmid date trait efo analysis source outcome exposure covariates outcome_units exposure_units methylation_array tissue further_details n n_cohorts age sex ethnicity cpg chrpos chr pos gene type beta se p details study_id Bonder MJ - 25282492 2014-10-04 Fetal vs adult liver UBERON_0002107, GO_0048513 - Additional file 2 DNA methylation Fetal vs adult liver Sex and technical covariates M values - Illumina HumanMethylation450 Liver - 195 2 - Missing None cg05005073 chr1:39513326 1 39513326 - Open sea -2.19906 0.07676 4.48e-46 - 25282492_fetal_vs_adult_liver Yao C FHS, KORA F4, BLSA, InCHIANTI 33752734 2021-03-22 Gene expression of Affymetrix ID: 2331178 (gene symbol: NDUFS5) None Meta-analysis Table S6 DNA methylation Gene expression of Affymetrix ID: 2331178 (gene symbol: NDUFS5) Age, sex, cell composition (reference based), batch effects Beta Values None Illumina HumanMethylation450 Whole blood None 4170 1 Adults Both Unclear cg05005073 chr1:39513326 1 39513326 - Open sea None None 1.7e-33 None 33752734_Yao-C_gene_expression_of_affymetrix_id__2331178__gene_symbol__ndufs5__meta-analysis Wozniak MB - 23526956 2013-03-05 Clear cell renal carcinoma EFO_0000349, EFO_0000681 - Table S6 DNA methylation Clear cell renal carcinoma - M values - Illumina HumanMethylation450 Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 1 63 Both European cg05005073 chr1:39513326 1 39513326 - Open sea - - 1.1900000000000001e-26 - 23526956_clear_cell_renal_carcinoma Battram T GEO 30602389 2020-09-15 Tissue None EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells None DNA methylation Tissue Batch effects, cell composition (reference free) Beta Values None Illumina HumanMethylation450 Buccal cells and peripheral blood mononuclear cells None 215 1 Children Both European cg05005073 chr1:39513326 1 39513326 - Open sea 0.05702 0.00481 9.7e-25 None 30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells Spiers H - 25650246 2015-02-03 Gestational age EFO_0005112, EFO_0000246 - Additional file 1 DNA methylation Gestational age Sex and technical covariates Beta values days Illumina HumanMethylation450 Fetal brain - 179 1 - Both None cg05005073 chr1:39513326 1 39513326 - Open sea -0.36359 0.0429 2.34e-17 - 25650246_gestational_age Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02748 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02748 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05005073 chr1:39513326 1 39513326 - Open sea -0.0551694 0.008244 0.00000000002280223 P02748 41361833_Josephine_Robertson_P02748_OSCA_model_1 Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 1 with age as a fixed effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg05005073 chr1:39513326 1 39513326 - Open sea -0.0011 0.00017 0.00000000009 None 33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P18428 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P18428 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05005073 chr1:39513326 1 39513326 - Open sea -0.0498984 0.00824629 0.000000001474377 P18428 41361833_Josephine_Robertson_P18428_OSCA_model_1 Robert F. Hillary Generation Scotland doi.org/10.1101/2023.11.02.23298000 Nov 3, 2023 C-reactive protein (CRP) levels None Basic model None C-reactive protein (CRP) levels DNA methylation Age, Sex, Cell composition (reference based), Batch effects mg/L Beta values Illumina HumanMethylationEPIC Whole blood None 17936 1 Adults Both European cg05005073 chr1:39513326 1 39513326 - Open sea -0.68 0.121 0.000000026 Basic_Model Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 O75882 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation O75882 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05005073 chr1:39513326 1 39513326 - Open sea 0.0448248 0.00824827 0.00000005584285 O75882 41361833_Josephine_Robertson_O75882_OSCA_model_1 Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg05005073 chr1:39513326 1 39513326 - Open sea 0.233 0.0000044 0.0000008 None 33741061_Moccia-C_birthweight_discovery Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02750 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02750 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05005073 chr1:39513326 1 39513326 - Open sea -0.0400341 0.00824995 0.000001230805 P02750 41361833_Josephine_Robertson_P02750_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P06396 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P06396 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05005073 chr1:39513326 1 39513326 - Open sea 0.038586 0.00825042 0.000002939133 P06396 41361833_Josephine_Robertson_P06396_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P01031 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P01031 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05005073 chr1:39513326 1 39513326 - Open sea -0.0381839 0.00825055 0.000003722907 P01031 41361833_Josephine_Robertson_P01031_OSCA_model_1 Robert F. Hillary Generation Scotland doi.org/10.1101/2023.11.02.23298000 Nov 3, 2023 C-reactive protein (CRP) levels None Fully-adjusted model None C-reactive protein (CRP) levels DNA methylation Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption mg/L Beta values Illumina HumanMethylationEPIC Whole blood None 14040 1 Adults Both European cg05005073 chr1:39513326 1 39513326 - Open sea -0.55 0.125 0.00001 Fully_Adjusted_Model Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P29622 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P29622 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05005073 chr1:39513326 1 39513326 - Open sea 0.033969 0.00825181 0.00003866825 P29622 41361833_Josephine_Robertson_P29622_OSCA_model_1 Gadd DA Generation Scotland 35945220 31/07/2022 GHDC protein levels (SeqId = 9730-22) None SomaScan protein measurement https://doi.org/10.5281/zenodo.6801458 GHDC protein levels (SeqId = 9730-22) DNA methylation Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking None M values Illumina HumanMethylationEPIC Whole blood Full UniProt name: GH3 domain-containing protein 774 1 Adults (18-65 years) Both European cg05005073 chr1:39513326 1 39513326 - Open sea 0.34 0.084 0.000041 None Gadd-DA_ghdc_protein_levels__seqid___9730-22__somascan_protein_measurement Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02671 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02671 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05005073 chr1:39513326 1 39513326 - Open sea -0.0327309 0.00825215 0.00007332904 P02671 41361833_Josephine_Robertson_P02671_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 O75882 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation O75882 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05005073 chr1:39513326 1 39513326 - Open sea 0.0331731 0.00836373 0.00007334243 O75882 41361833_Josephine_Robertson_O75882_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 O75882 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation O75882 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05005073 chr1:39513326 1 39513326 - Open sea 0.0324442 0.00833155 0.00009898643 O75882 41361833_Josephine_Robertson_O75882_OSCA_model_3