author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0087	0.00021	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.027	0.00093	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.31911	0.00459	1.6e-138	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-	-	4.3499999999999997e-135	-	28056824_age_4_vs_age_0
Mandaviya PR	RS, LLS, LL, NTR, CODAM, MARTHA, EGCUT, F5L, FHS, KORA, LBC1921, LBC1936	29084233	2017-10-30	homocysteine (MTHFR 677C>T)	CHEBI_17230, EFO_0004578	Meta-analysis	Table S3	DNA methylation	homocysteine (MTHFR 677C>T)	age, sex, cell composition (reference free), batch effects	Beta Values	allele copy number	Illumina HumanMethylation450	Whole blood	None	9894	12	Adults	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.007	0.001	9.2e-43	None	29084233_Mandaviya-PR_homocysteine__mthfr_677c_t__meta-analysis
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	2.25438	0.09534	1.21e-39	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.096688	0.00821789	8.164432000000001e-32	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mandaviya PR	RS, LLS, LL, NTR, CODAM, MARTHA, EGCUT, F5L, FHS, KORA, LBC1921, LBC1936	29084233	2017-10-30	homocysteine GRS	CHEBI_17230, EFO_0004578	Meta-analysis	Table S4	DNA methylation	homocysteine GRS	age, sex, cell composition (reference free), batch effects	Beta Values	GRS SD	Illumina HumanMethylation450	Whole blood	None	9894	12	Adults	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.016	0.002	4.5e-18	None	29084233_Mandaviya-PR_homocysteine_grs_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0712528	0.00823559	5.588929e-18	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.055	0.00681	0.000000000000001	None	Robert-F-Hillary_Incident_COPD_Basic_model
Li S	-	28811542	2017-08-15	Age	EFO_0000246	-	Table S1	DNA methylation	Age	Cell counts	M values	years	Illumina HumanMethylation450	Whole blood	-	1366	2	73	Missing	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.00877	0.0011351	0.00000000000000554	-	28811542_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0637249	0.00823979	0.00000000000001111484	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0635061	0.00823991	0.00000000000001369008	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.13522	0.0177	0.0000000000000207	-	25650246_gestational_age
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.00583	0.00076	0.000000000000025	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.00074	0.0001	0.0000000000022	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.00075891	0.00011233	0.0000000000233	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0085	0.0014	0.00000000064	-	27651444_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0528612	0.00870042	0.000000001264979	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-	-	0.00000000418	-	26857698_primary_sjogrens_syndrome_whole_blood
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0007261	0.00012468	0.00000000765	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0468603	0.0082475	0.00000001358527	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Guida F	-	25556184	2015-04-15	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S1	DNA methylation	Smoking	Cell counts and technical covariates	M values	-	Illumina HumanMethylation450	Whole blood	-	582	2	54	Females	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.09	0.0164	0.00000004	-	25556184_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0476716	0.00872151	0.00000004678631	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0430731	0.00824891	0.0000001797424	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0430469	0.00824892	0.0000001828483	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.042923	0.00824896	0.0000001982639	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0423404	0.00824917	0.0000002892915	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0423316	0.00824917	0.0000002909221	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.042182	0.00824922	0.0000003203173	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Sharp GC	-	28603561	2017-06-08	Cleft palate vs cleft lip	EFO_0003959, HP_0000175	-	Additional file 5	DNA methylation	Cleft palate vs cleft lip	Sex and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	98	1	0	Both	European,Other	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.04285113	0.00774007	0.000000345	-	28603561_cleft_palate_vs_cleft_lip
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0413616	0.00824951	0.0000005398063	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.040389	0.00824983	0.0000009897894	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-1.3	0.273	0.0000027	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0413998	0.00881992	0.000002704729	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0381584	0.00825056	0.000003778877	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0376606	0.00825071	0.000005047006	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0403926	0.00886833	0.000005288246	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0373578	0.00825081	0.000006007655	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0369081	0.00825095	0.000007763617	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0365292	0.00825106	0.000009615006	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0364038	0.0082511	0.0000103153	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0362593	0.00825114	0.00001118281	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.036175	0.00825117	0.00001172046	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0457188	0.0104466	0.00001214746	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0357191	0.0082513	0.00001508472	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0384248	0.00887768	0.00001512936	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_3
Zhu X	-	26756918	2016-07-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	-	Table S1	DNA methylation	Smoking	Age, sex, alcohol consumption, body mass index and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	Regression coefficients are for inverse normally transformed DNA methylation	596	4	53.9	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.152	0.035435	0.0000179	-	26756918_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0352476	0.00825144	0.00001952211	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0377272	0.00886119	0.00002079419	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	-0.0350395	0.0082515	0.00002185291	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0349288	0.00825153	0.00002319928	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0346046	0.00825163	0.00002760842	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05228408	chr1:11865352	1	11865352	CLCN6;MTHFR	North shore	0.0332223	0.00825201	0.00005702746	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_1