author consortium pmid date trait efo analysis source outcome exposure covariates outcome_units exposure_units methylation_array tissue further_details n n_cohorts age sex ethnicity cpg chrpos chr pos gene type beta se p details study_id Battram T GEO 30602389 2020-09-15 Tissue None EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells None DNA methylation Tissue Batch effects, cell composition (reference free) Beta Values None Illumina HumanMethylation450 Buccal cells and peripheral blood mononuclear cells None 215 1 Children Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore 0.4057 0.00562 1.4e-141 None 30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells Yao C FHS, KORA F4, BLSA, InCHIANTI 33752734 2021-03-22 Gene expression of Affymetrix ID: 2621917 (gene symbol: WDR6) None Meta-analysis Table S6 DNA methylation Gene expression of Affymetrix ID: 2621917 (gene symbol: WDR6) Age, sex, cell composition (reference based), batch effects Beta Values None Illumina HumanMethylation450 Whole blood None 4170 1 Adults Both Unclear cg05785598 chr3:49045655 3 49045655 WDR6 South shore None None 2.8e-26 None 33752734_Yao-C_gene_expression_of_affymetrix_id__2621917__gene_symbol__wdr6__meta-analysis Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02775 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02775 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore -0.0468165 0.00824752 0.00000001401383 P02775 41361833_Josephine_Robertson_P02775_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02775 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P02775 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore -0.0431952 0.00828142 0.0000001853908 P02775 41361833_Josephine_Robertson_P02775_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02775 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation P02775 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore -0.0425371 0.00827937 0.0000002816686 P02775 41361833_Josephine_Robertson_P02775_OSCA_model_3 Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 2 at 9y with age as a fixed effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore 0.0079 0.0016 0.0000013 None 33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P07996 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P07996 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore -0.0401175 0.00829956 0.000001353817 P07996 41361833_Josephine_Robertson_P07996_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P07996 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P07996 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore -0.0393397 0.00825018 0.000001875293 P07996 41361833_Josephine_Robertson_P07996_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P07996 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation P07996 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore -0.0392764 0.00829239 0.000002195419 P07996 41361833_Josephine_Robertson_P07996_OSCA_model_3 Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 2 at 6y with age as a fixed effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore 0.0081 0.0017 0.0000028 None 33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 1 with age as a fixed effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore -0.0012 0.00026 0.0000031 None 33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect Dugue P-A Melbourne Collaborative Cohort Study 31789449 2019-11-04 Alcohol consumption EFO_0004329, EFO_0007878 Previous week consumption discovery Supplementary Table 3 Alcohol consumption DNA methylation age, sex, smoking, body mass index country of birth, sample type, cell composition (reference based), batch effects g/day M Values Illumina HumanMethylation450 Whole blood None 5606 1 Adults Both Unclear cg05785598 chr3:49045655 3 49045655 WDR6 South shore None None 0.000028 None 31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery Gadd DA Generation Scotland 35945220 31/07/2022 CLEC11A protein levels (SeqId = 4500-50) None SomaScan protein measurement https://doi.org/10.5281/zenodo.6801458 CLEC11A protein levels (SeqId = 4500-50) DNA methylation Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking None M values Illumina HumanMethylationEPIC Whole blood Full UniProt name: C-type lectin domain family 11 member A 774 1 Adults (18-65 years) Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore -0.53 0.13 0.000041 None Gadd-DA_clec11a_protein_levels__seqid___4500-50__somascan_protein_measurement Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P14151 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P14151 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore -0.033523 0.00829461 0.00005337305 P14151 41361833_Josephine_Robertson_P14151_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P14151 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation P14151 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore -0.0331013 0.00823849 0.00005901503 P14151 41361833_Josephine_Robertson_P14151_OSCA_model_3 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P08603 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P08603 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore 0.0332804 0.00828697 0.00005949244 P08603 41361833_Josephine_Robertson_P08603_OSCA_model_2 Dugue P-A Melbourne Collaborative Cohort Study 31789449 2019-11-04 Alcohol consumption EFO_0004329, EFO_0007878 Previous decade consumption discovery Supplementary Table 3 Alcohol consumption DNA methylation age, sex, smoking, body mass index country of birth, sample type, cell composition (reference based), batch effects g/day M Values Illumina HumanMethylation450 Whole blood None 5606 1 Adults Both Unclear cg05785598 chr3:49045655 3 49045655 WDR6 South shore None None 0.000081 None 31789449_Dugue-P-A_alcohol_consumption_previous_decade_consumption_discovery Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P14151 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P14151 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg05785598 chr3:49045655 3 49045655 WDR6 South shore -0.0324076 0.00825223 0.00008635862 P14151 41361833_Josephine_Robertson_P14151_OSCA_model_1