author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Breast Cancer (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Breast Cancer (Self-report)	Age, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	10650	1	Adults (18-65y)	Females	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	-0.51	0.0203	7.3e-135	None	Robert-F-Hillary_Prevalent_Breast_Cancer_(Self-report)_Basic_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Breast Cancer (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Breast Cancer (Self-report)	Age, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	8260	1	Adults (18-65y)	Females	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	-0.5	0.023	2.4e-101	None	Robert-F-Hillary_Prevalent_Breast_Cancer_(Self-report)_Fully-adjusted_model
McCartney DL	Generation Scotland: Scottish Family Health Study	31892350	2019-12-31	Age-by-sex interaction	EFO_0000246, PATO_0000047	Replication using MOMENT (mixed linear model-based method)	Table 1	DNA methylation	Age-by-sex interaction	Age, sex, cell composition (reference free), batch effects	Beta Values	None	Illumina HumanMethylationEPIC	Whole Blood	None	4450	1	Adults	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.49	0.05	1e-22	None	31892350_McCartney-DL_age-by-sex_interaction_replication_using_moment__mixed_linear_model-based_method_
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0838739	0.00866062	4.0870950000000004e-22	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0792762	0.00834426	2.401619e-21	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.073499	0.00868119	2.766824e-17	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0873795	0.0105767	1.561259e-16	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0689137	0.00842529	3.08544e-16	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0651292	0.00823904	0.000000000000002870326	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0813317	0.0106931	0.00000000000002998277	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0582141	0.00824257	0.000000000001707407	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
McCartney DL	Generation Scotland: Scottish Family Health Study	31892350	2019-12-31	Age-by-sex interaction	EFO_0000246, PATO_0000047	Discovery using MOMENT (mixed linear model-based method)	Table 1	DNA methylation	Age-by-sex interaction	Age, sex, cell composition (reference free), batch effects	Beta Values	None	Illumina HumanMethylationEPIC	Whole Blood	None	2586	1	Adults	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.33	0.049	0.0000000000072	None	31892350_McCartney-DL_age-by-sex_interaction_discovery_using_moment__mixed_linear_model-based_method_
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	-0.323131	0.0533057	0.000000001373665	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0575597	0.0109824	0.0000001618356	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0431608	0.00824888	0.0000001696996	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.038	0.00756	0.00000068	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	-0.0390225	0.00825028	0.00000226792	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0510364	0.0110325	0.000003759841	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0401126	0.00868843	0.000003930377	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0391768	0.00868231	0.000006463998	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0389243	0.00866825	0.000007161848	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	-0.0366495	0.00825102	0.0000089859	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	-0.233539	0.0534837	0.00001269566	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	-0.0372868	0.00870595	0.00001856348	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0361004	0.00855583	0.0000246434	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	-0.0347196	0.00825159	0.00002596111	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0360718	0.00864258	0.00003013778	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	-0.0360404	0.00870713	0.00003504844	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0359381	0.00869858	0.00003624124	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0352831	0.00854361	0.00003651396	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	-0.0329981	0.00825208	0.00006398514	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	-0.0438963	0.011027	0.00006900939	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0324781	0.00825222	0.0000833447	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0339907	0.00870873	0.00009540777	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06123699	chr3:188817035	3	188817035	-	Open sea	0.0431412	0.0110625	0.00009670951	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_4