author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.00061	0.000071	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.61927	0.0083	2.7e-144	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3511698 (gene symbol: EPSTI1)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3511698 (gene symbol: EPSTI1)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	None	None	3.8e-31	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3511698__gene_symbol__epsti1__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0663208	0.00823839	8.895621e-16	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0688265	0.00869165	0.0000000000000025719	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0638232	0.00834805	0.00000000000002214011	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.00058	None	0.00000000000059	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.15407	0.0219	0.00000000000183	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0569786	0.00839211	0.00000000001168151	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Chung SA	-	26192630	2015-07-20	Autoantibody production in systemic lupus erythematosus	EFO_0004866, EFO_0002690	Combined	Table S1	DNA methylation	Autoantibody production in systemic lupus erythematosus	Age, disease duration, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	Wilcoxon rank sum test	326	2	46	Females	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-	-	0.00000000025	-	26192630_autoantibody_production_in_systemic_lupus_erythematosus_combined
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0456501	0.00824796	0.00000003170905	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0464068	0.00840594	0.00000003433689	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0461427	0.00840059	0.00000004022096	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0461372	0.00840721	0.00000004136907	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0447523	0.0082483	0.0000000586621	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-	-	0.000000102	-	26857698_primary_sjogrens_syndrome_whole_blood
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.219775	0.0412727	0.0000001022371	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0438009	0.00840826	0.0000001921528	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0435756	0.00874797	0.0000006390457	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0406607	0.00824974	0.0000008367445	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0406298	0.00838441	0.000001273424	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0394787	0.00871293	0.000005915567	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0016	None	0.00001	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0359169	0.00825124	0.00001352549	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0362309	0.00836639	0.00001497364	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0373791	0.0086661	0.00001619206	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0350647	0.00841401	0.00003098381	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0342383	0.00825173	0.00003354736	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0335515	0.00820988	0.0000439838	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0343425	0.00840395	0.00004403123	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0336846	0.00825189	0.00004487773	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0335484	0.00825192	0.00004817522	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0340228	0.00841727	0.00005326395	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0338719	0.00839042	0.00005442149	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.0330937	0.00825205	0.00006092656	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0330655	0.00830665	0.00006907149	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0339702	0.00854636	0.00007077159	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.163769	0.0413823	0.00007605193	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.034538	0.00876395	0.00008154669	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	0.032985	0.00841074	0.00008829984	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02749	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02749	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06146977	chr13:43469464	13	43469464	EPSTI1	Open sea	-0.0343123	0.00878082	0.00009362241	P02749	41361833_Josephine_Robertson_P02749_OSCA_model_4