author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	0.0037	0.00023	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	0.06708	0.00338	1.5e-48	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Walker R	Generation Scotland	33397400	2021-01-04	APOE e2 vs e4	EFO_0007659	Meta-analysis	Table 1	DNA methylation	APOE e2 vs e4	age, sex, smoking, cell composition (reference based), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	3587	1	Adults	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	0.112	0.008	1.1e-44	Effect direction is relative to carriers of the e2 allele	33397400_Walker-R_apoe_e2_vs_e4_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	0.0018	None	0.00000000019	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	-0.0485529	0.00824683	0.000000004007554	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	-0.0508328	0.00916089	0.00000002924659	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	0.0448041	0.00824657	0.00000005628217	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	0.044567	0.00833667	0.00000009131657	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	-0.0419302	0.00843466	0.0000006729905	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	-0.0416	0.00843294	0.000000818497	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_2
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	0.2022	0.0416	0.00000115	-	27105112_hiv_infection_neutrophils
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	0.0408242	0.0089381	0.00000497748	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	0.124301	0.0277747	0.000007675806	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	-0.0069	0.0016	0.000016	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	0.128916	0.0300795	0.00001829694	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Gadd DA	Generation Scotland	35945220	31/07/2022	EPO protein levels (SeqId = 5813-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPO protein levels (SeqId = 5813-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Erythropoietin	774	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	-0.63	0.15	0.00003	None	Gadd-DA_epo_protein_levels__seqid___5813-58__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KIR3DL3 protein levels (SeqId = 7944-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIR3DL3 protein levels (SeqId = 7944-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Killer cell immunoglobulin-like receptor 3DL3	774	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	-0.62	0.151	0.000044	None	Gadd-DA_kir3dl3_protein_levels__seqid___7944-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADAM17 protein levels (SeqId = 8882-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADAM17 protein levels (SeqId = 8882-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Disintegrin and metalloproteinase domain-containing protein 17	774	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	-0.61	0.151	0.000053	None	Gadd-DA_adam17_protein_levels__seqid___8882-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SEMA3E protein levels (SeqId = 5363-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SEMA3E protein levels (SeqId = 5363-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Semaphorin-3E	774	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	-0.6	0.15	0.000065	None	Gadd-DA_sema3e_protein_levels__seqid___5363-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	JAG2 protein levels (SeqId = 5093-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	JAG2 protein levels (SeqId = 5093-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein jagged-2	774	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	-0.6	0.151	0.000068	None	Gadd-DA_jag2_protein_levels__seqid___5093-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLEC2B protein levels (SeqId = 7786-83)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLEC2B protein levels (SeqId = 7786-83)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-type lectin domain family 2 member B	774	1	Adults (18-65 years)	Both	European	cg06750524	chr19:45409955	19	45409955	APOE	North shore	-0.59	0.151	0.000095	None	Gadd-DA_clec2b_protein_levels__seqid___7786-83__somascan_protein_measurement