author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	0.00092	0.000087	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	0.06004	0.00314	1.8e-46	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	0.00092	None	1.6999999999999998e-31	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3375545 (gene symbol: FADS1)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3375545 (gene symbol: FADS1)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg07689907	chr11:61582574	11	61582574	FADS1	Island	None	None	1.6000000000000002e-22	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3375545__gene_symbol__fads1__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	0.0582387	0.00824256	0.000000000001671146	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	-0.0535422	0.00824473	0.00000000008621097	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Petersen A-K	KORA F4	24014485	2013-09-06	M02730_gamma-glutamylglutamine	EFO_0004727, EFO_0004725	no snps model	Table S2	M02730_gamma-glutamylglutamine	DNA methylation	Age, sex, body mass index, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1760	1	Adults	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	24	0.23	0.00000000084	None	24014485_Petersen-A-K_m02730_gamma-glutamylglutamine_no_snps_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	-0.0436371	0.00824871	0.0000001239544	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	0.0024	None	0.0000093	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	0.110988	0.0266771	0.00003191423	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	-0.0342994	0.00825171	0.00003247989	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Battram T	ARIES	None	2020-08-20	Estimated degree of fatty acid unsaturation	EFO_0005110	None	None	DNA methylation	Estimated degree of fatty acid unsaturation	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	672	1	Adults	Females	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	2.03	0.49	0.000043	None	Battram-T_estimated_degree_of_fatty_acid_unsaturation
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	-0.0332458	0.00825201	0.00005634055	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	-0.0330463	0.00825206	0.00006242466	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07689907	chr11:61582574	11	61582574	FADS1	Island	0.0342635	0.00865035	0.0000750094	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
