author consortium pmid date trait efo analysis source outcome exposure covariates outcome_units exposure_units methylation_array tissue further_details n n_cohorts age sex ethnicity cpg chrpos chr pos gene type beta se p details study_id Battram T GEO 30602389 2020-09-15 Tissue None EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells None DNA methylation Tissue Batch effects, cell composition (reference free) Beta Values None Illumina HumanMethylation450 Buccal cells and peripheral blood mononuclear cells None 215 1 Children Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island 0.14309 0.0057 9.5e-63 None 30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells Yao C FHS, KORA F4, BLSA, InCHIANTI 33752734 2021-03-22 Gene expression of Affymetrix ID: 2709606 (gene symbol: RPL39L) None Meta-analysis Table S6 DNA methylation Gene expression of Affymetrix ID: 2709606 (gene symbol: RPL39L) Age, sex, cell composition (reference based), batch effects Beta Values None Illumina HumanMethylation450 Whole blood None 4170 1 Adults Both Unclear cg07693270 chr3:186856928 3 186856928 RPL39L Island None None 2.4e-16 None 33752734_Yao-C_gene_expression_of_affymetrix_id__2709606__gene_symbol__rpl39l__meta-analysis Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02748 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02748 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island 0.0668024 0.00823813 5.508286e-16 P02748 41361833_Josephine_Robertson_P02748_OSCA_model_1 Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 1 with age as a fixed effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island 0.0009 0.00016 0.000000023 None 33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02750 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02750 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island 0.0437876 0.00824865 0.0000001121666 P02750 41361833_Josephine_Robertson_P02750_OSCA_model_1 Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 2 at 6y with age as a fixed effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island -0.0059 0.0011 0.00000022 None 33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect Mulder RH ALSPAC,Generation R 33450751 25/01/2021 sex PATO_0000047 Discovery http://epidelta.mrcieu.ac.uk/ DNA methylation sex gestational age,cohort,cell composition (reference based),batch effects Beta Values None Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island -0.011 0.0022 0.00000023 None 33450751_Mulder-RH_sex_discovery Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P04430 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P04430 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island -0.0391326 0.00825025 0.000002123462 P04430 41361833_Josephine_Robertson_P04430_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P00747 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P00747 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island -0.0407424 0.00878026 0.000003510493 P00747 41361833_Josephine_Robertson_P00747_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P08185 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P08185 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island -0.0379848 0.00825061 0.000004181846 P08185 41361833_Josephine_Robertson_P08185_OSCA_model_1 Gadd DA Generation Scotland 35945220 31/07/2022 CA7 protein levels (SeqId = 3356-50) None SomaScan protein measurement https://doi.org/10.5281/zenodo.6801458 CA7 protein levels (SeqId = 3356-50) DNA methylation Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking None M values Illumina HumanMethylationEPIC Whole blood Full UniProt name: Carbonic anhydrase 7 774 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island -0.7 0.154 0.0000057 None Gadd-DA_ca7_protein_levels__seqid___3356-50__somascan_protein_measurement Dugue P-A Melbourne Collaborative Cohort Study 31789449 2019-11-04 Alcohol consumption EFO_0004329, EFO_0007878 Previous week consumption discovery Supplementary Table 3 Alcohol consumption DNA methylation age, sex, smoking, body mass index country of birth, sample type, cell composition (reference based), batch effects g/day M Values Illumina HumanMethylation450 Whole blood None 5606 1 Adults Both Unclear cg07693270 chr3:186856928 3 186856928 RPL39L Island None None 0.0000068 None 31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02790 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02790 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island 0.0369362 0.00825094 0.000007641123 P02790 41361833_Josephine_Robertson_P02790_OSCA_model_1 Dugue P-A Melbourne Collaborative Cohort Study 31789449 2019-11-04 Alcohol consumption EFO_0004329, EFO_0007878 Lifetime consumption discovery Supplementary Table 3 Alcohol consumption DNA methylation age, sex, smoking, body mass index country of birth, sample type, cell composition (reference based), batch effects g/day M Values Illumina HumanMethylation450 Whole blood None 5606 1 Adults Both Unclear cg07693270 chr3:186856928 3 186856928 RPL39L Island None None 0.000012 None 31789449_Dugue-P-A_alcohol_consumption_lifetime_consumption_discovery Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P18428 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P18428 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island 0.0350173 0.00825151 0.00002211706 P18428 41361833_Josephine_Robertson_P18428_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P00747 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation P00747 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island -0.0366173 0.00878556 0.00003091946 P00747 41361833_Josephine_Robertson_P00747_OSCA_model_3 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P04430 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation P04430 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island -0.0357244 0.00881776 0.00005117207 P04430 41361833_Josephine_Robertson_P04430_OSCA_model_3 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 B1AHL2 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation B1AHL2 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island 0.0353276 0.00878322 0.00005795281 B1AHL2 41361833_Josephine_Robertson_B1AHL2_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P08571 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P08571 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg07693270 chr3:186856928 3 186856928 RPL39L Island -0.0352366 0.0087846 0.00006071537 P08571 41361833_Josephine_Robertson_P08571_OSCA_model_2