author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.013	0.0004	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	0.051	0.0021	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3238761 (gene symbol: MSRB2)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3238761 (gene symbol: MSRB2)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	None	None	3.8e-22	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3238761__gene_symbol__msrb2__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.0632986	0.00948581	0.00000000002596519	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.0055	0.00079	0.00000000021	None	33564054_Kashima-K_gestational_age
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.16953	0.0272	0.000000000455	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.0579739	0.0094362	0.0000000008266858	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.0472202	0.00824736	0.00000001051571	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	0.0397513	0.00825005	0.000001462215	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.0383447	0.0082505	0.000003388039	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.0373607	0.00825081	0.000005997791	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.0370827	0.00825089	0.000007030511	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	0.0370735	0.0082509	0.00000706723	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.0369887	0.00825092	0.000007416587	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Karlsson Linner R	-	29086770	2017-10-31	Educational attainment	EFO_0004784	Basic model	Table S1.6b	DNA methylation	Educational attainment	Age, sex, cell counts and technical covariates	Beta values	years of schooling	Illumina HumanMethylation450	Whole blood	-	10767	27	57	Both	None	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-	-	0.00000812	-	29086770_educational_attainment_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	TMEM2 protein levels (SeqId = 8992-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMEM2 protein levels (SeqId = 8992-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cell surface hyaluronidase	774	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.57	0.131	0.000016	None	Gadd-DA_tmem2_protein_levels__seqid___8992-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	0.0348184	0.00825157	0.0000246192	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	IAPP protein levels (SeqId = 19639-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IAPP protein levels (SeqId = 19639-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Islet amyloid polypeptide	774	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.55	0.131	0.000029	None	Gadd-DA_iapp_protein_levels__seqid___19639-53__somascan_protein_measurement
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.00071	0.00017	0.000034	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.0391455	0.00949305	0.00003750559	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	SMPD1 protein levels (SeqId = 10818-36)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMPD1 protein levels (SeqId = 10818-36)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sphingomyelin phosphodiesterase	774	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.54	0.131	0.000039	None	Gadd-DA_smpd1_protein_levels__seqid___10818-36__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.037914	0.00950705	0.00006695832	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07834396	chr10:23385979	10	23385979	MSRB2	South shore	-0.0370807	0.00948366	0.00009273087	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2