author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.031	0.0014	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.011	0.0013	0	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.114392	0.00820237	6.323953999999999e-44	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.124503	0.00904501	7.663387e-43	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.117556	0.00854905	9.279149000000001e-43	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.117003	0.00857152	3.644775e-42	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.122026	0.00906114	4.295585e-41	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.110986	0.00855453	2.7936339999999996e-38	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.110145	0.00858382	1.734025e-37	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.103186	0.0082125	5.0729329999999996e-36	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.105966	0.00854075	3.588484e-35	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.106015	0.00901393	8.59181e-32	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0995987	0.00854089	2.758644e-31	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.102992	0.00902552	4.9233969999999995e-30	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0931374	0.00822068	1.2425560000000001e-29	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.100277	0.00905193	2.080903e-28	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0943759	0.00857885	4.8646960000000005e-28	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0936073	0.00853824	7.360207000000001e-28	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.093726	0.00856231	8.861289e-28	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0882327	0.00822437	9.43082e-27	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0882013	0.00822439	9.828007e-27	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0910286	0.00857019	2.9477329999999997e-26	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0866502	0.00822552	7.423447e-26	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0949633	0.00906916	1.445113e-25	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0890223	0.00856849	3.3854060000000003e-25	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0887483	0.00859558	6.620051e-25	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.284554	0.0291987	2.188265e-22	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0800825	0.00823005	2.610587e-22	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0797789	0.00855312	1.236779e-20	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0839296	0.00902454	1.597332e-20	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.285499	0.0309635	3.271617e-20	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0787624	0.00855525	3.823849e-20	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0782976	0.00858932	8.814085999999999e-20	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0781603	0.00861728	1.336828e-19	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	MX1 protein levels (SeqId = 17460-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MX1 protein levels (SeqId = 17460-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon-induced GTP-binding protein Mx1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-1.24	0.137	1.5e-19	None	Gadd-DA_mx1_protein_levels__seqid___17460-51__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0774216	0.00861671	2.8968679999999997e-19	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0809874	0.00909831	6.154145999999999e-19	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0742246	0.00855947	4.7011030000000004e-18	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0708743	0.00823581	8.352127e-18	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01766	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01766	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0740101	0.00861442	9.447753e-18	P01766	41361833_Josephine_Robertson_P01766_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0780378	0.00908924	9.924802e-18	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	ISG15 protein levels (SeqId = 14151-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ISG15 protein levels (SeqId = 14151-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-like protein ISG15	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-1.16	0.137	2.4e-17	None	Gadd-DA_isg15_protein_levels__seqid___14151-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01766	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01766	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0766128	0.00910017	4.152061e-17	P01766	41361833_Josephine_Robertson_P01766_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01766	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01766	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0714121	0.00858884	1.001537e-16	P01766	41361833_Josephine_Robertson_P01766_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0697421	0.00843545	1.481403e-16	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0709372	0.00858499	1.542108e-16	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.071129	0.00860959	1.559403e-16	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.248709	0.030231	2.055664e-16	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0744257	0.0090882	2.843824e-16	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0670626	0.00820491	3.239896e-16	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0686687	0.00844852	4.715092e-16	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0697849	0.00860501	5.469592e-16	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.06892	0.00858732	0.000000000000001084843	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_2
Mendelson MM	FHS	29740313	2018-04-24	Soluble tumor necrosis factor receptor 2	EFO_0008384, NCIT_C117749	None	Table S1	DNA methylation	Soluble tumor necrosis factor receptor 2	Age, sex, body mass index, smoking, batch effects	Beta Values	pg/ml	Illumina HumanMethylation450	Whole blood	None	2468	1	Adults	Both	Unclear	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0196	0.00243	0.0000000000000012	None	29740313_Mendelson-MM_soluble_tumor_necrosis_factor_receptor_2
Gadd DA	Generation Scotland	35945220	31/07/2022	GBP1 protein levels (SeqId = 15326-64)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GBP1 protein levels (SeqId = 15326-64)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Guanylate-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-1.07	0.135	0.0000000000000017	None	Gadd-DA_gbp1_protein_levels__seqid___15326-64__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01766	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01766	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0655559	0.00823881	0.000000000000001891574	P01766	41361833_Josephine_Robertson_P01766_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0682439	0.00857895	0.000000000000001924529	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0672592	0.0084806	0.000000000000002331024	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0652823	0.00823896	0.000000000000002472125	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0714227	0.00901637	0.000000000000002515852	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0652616	0.00823897	0.000000000000002522622	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0700043	0.00884881	0.000000000000002731753	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0673905	0.00853273	0.000000000000003037097	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.243145	0.0308596	0.000000000000003483076	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0670182	0.00859295	0.000000000000006647919	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0696945	0.00900055	0.00000000000001031503	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.241573	0.0316477	0.00000000000002409208	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0651832	0.0085861	0.0000000000000334717	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0653283	0.00861417	0.00000000000003556235	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_3
Chung SA	-	26192630	2015-07-20	Autoantibody production in systemic lupus erythematosus	EFO_0004866, EFO_0002690	Combined	Table S1	DNA methylation	Autoantibody production in systemic lupus erythematosus	Age, disease duration, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	Wilcoxon rank sum test	326	2	46	Females	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-	-	0.000000000000037	-	26192630_autoantibody_production_in_systemic_lupus_erythematosus_combined
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0641518	0.00858999	0.0000000000000858798	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0646086	0.00879335	0.0000000000002127035	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0622689	0.0085374	0.0000000000003170928	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0600636	0.00824166	0.0000000000003311283	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0595419	0.00824192	0.0000000000005285824	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04430	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04430	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0657414	0.00910821	0.0000000000005542792	P04430	41361833_Josephine_Robertson_P04430_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0653678	0.00909058	0.0000000000006757334	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0595972	0.00847477	0.000000000002121224	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.057723	0.0082428	0.000000000002617427	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0585534	0.00837653	0.000000000002863922	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04430	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04430	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0600703	0.00862421	0.00000000000341616	P04430	41361833_Josephine_Robertson_P04430_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CXCL11 protein levels (SeqId = 3038-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXCL11 protein levels (SeqId = 3038-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-X-C motif chemokine 11	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.95	0.137	0.0000000000036	None	Gadd-DA_cxcl11_protein_levels__seqid___3038-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0585483	0.00844401	0.000000000004270972	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.060869	0.00884094	0.000000000006018269	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04430	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04430	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0566177	0.00824333	0.000000000006758444	P04430	41361833_Josephine_Robertson_P04430_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	LAG3 protein levels (SeqId = 9950-229)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LAG3 protein levels (SeqId = 9950-229)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lymphocyte activation gene 3 protein	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.94	0.137	0.0000000000072	None	Gadd-DA_lag3_protein_levels__seqid___9950-229__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDX58 protein levels (SeqId = 12382-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDX58 protein levels (SeqId = 12382-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable ATP-dependent RNA helicase DDX58	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.93	0.137	0.00000000001	None	Gadd-DA_ddx58_protein_levels__seqid___12382-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0618133	0.00908941	0.00000000001082325	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04430	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04430	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0584122	0.0085977	0.00000000001133167	P04430	41361833_Josephine_Robertson_P04430_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0559649	0.00824363	0.00000000001173606	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0581593	0.00858605	0.00000000001303131	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CD48 protein levels (SeqId = 3292-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD48 protein levels (SeqId = 3292-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: CD48 antigen	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.92	0.137	0.00000000002	None	Gadd-DA_cd48_protein_levels__seqid___3292-75__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0576686	0.00860405	0.00000000002123628	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0568334	0.00858424	0.00000000003700167	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0594928	0.00903857	0.00000000004795947	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	IFIT3 protein levels (SeqId = 13642-90)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFIT3 protein levels (SeqId = 13642-90)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon-induced protein with tetratricopeptide repeats 3	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.9	0.137	0.000000000052	None	Gadd-DA_ifit3_protein_levels__seqid___13642-90__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.19182	0.0293285	0.00000000006299417	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0535249	0.00824474	0.00000000008742026	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0556543	0.00859231	0.00000000009640402	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0582773	0.00900337	0.00000000009924395	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0552935	0.00856746	0.0000000001124324	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.053061	0.00824494	0.0000000001268224	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0581901	0.00906533	0.0000000001414252	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0581598	0.00909883	0.0000000001686782	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0547898	0.00857909	0.0000000001749167	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	STAT1 protein levels (SeqId = 10370-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAT1 protein levels (SeqId = 10370-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Signal transducer and activator of transcription 1-alpha/beta	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.87	0.137	0.00000000018	None	Gadd-DA_stat1_protein_levels__seqid___10370-21__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0547275	0.00859769	0.0000000002006101	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.054553	0.00860395	0.0000000002357992	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0522658	0.00824529	0.0000000002382254	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0536939	0.00849858	0.0000000002726414	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0565262	0.00895464	0.0000000002824626	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0538823	0.00855531	0.0000000003098776	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0516221	0.00824556	0.0000000003941985	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	B2M protein levels (SeqId = 3485-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	B2M protein levels (SeqId = 3485-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-2-microglobulin	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.85	0.137	0.00000000043	None	Gadd-DA_b2m_protein_levels__seqid___3485-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0534183	0.0085598	0.0000000004478723	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	COLEC12 protein levels (SeqId = 5457-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COLEC12 protein levels (SeqId = 5457-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collectin-12	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.85	0.137	0.00000000054	None	Gadd-DA_colec12_protein_levels__seqid___5457-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.052203	0.00840827	0.0000000005492343	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0530469	0.00858044	0.0000000006484724	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0531292	0.00860535	0.0000000006835241	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.050854	0.00824589	0.0000000007133636	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0560189	0.00910937	0.0000000007970314	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0526192	0.00856313	0.0000000008210631	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	NMI protein levels (SeqId = 17512-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NMI protein levels (SeqId = 17512-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-myc-interactor	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.84	0.137	0.0000000011	None	Gadd-DA_nmi_protein_levels__seqid___17512-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0520105	0.0086223	0.00000000165742	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0497411	0.00824635	0.000000001659468	A0A0B4J1V2	41361833_Josephine_Robertson_A0A0B4J1V2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0518904	0.00860481	0.000000001674888	A0A0B4J1V2	41361833_Josephine_Robertson_A0A0B4J1V2_OSCA_model_2
Chung SA	-	26192630	2015-07-20	Autoantibody production in systemic lupus erythematosus	EFO_0004866, EFO_0002690	Linear regression model	Table 2	DNA methylation	Autoantibody production in systemic lupus erythematosus	Age, ethnicity, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	-	326	2	46	Females	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.11	0.0184	0.0000000024	-	26192630_autoantibody_production_in_systemic_lupus_erythematosus_linear_regression_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0511974	0.00857737	0.000000002443745	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0490024	0.00824665	0.000000002877699	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0538697	0.00906597	0.000000002880057	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	CHST12 protein levels (SeqId = 6626-81)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHST12 protein levels (SeqId = 6626-81)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Carbohydrate sulfotransferase 12	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.81	0.137	0.0000000033	None	Gadd-DA_chst12_protein_levels__seqid___6626-81__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0508819	0.00859659	0.000000003314424	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0508376	0.00861266	0.000000003655809	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0486347	0.0082468	0.000000003773816	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CXCL10 protein levels (SeqId = 4141-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXCL10 protein levels (SeqId = 4141-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-X-C motif chemokine 10	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.81	0.137	0.0000000039	None	Gadd-DA_cxcl10_protein_levels__seqid___4141-79__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0508371	0.00863191	0.000000003960007	A0A0B4J1V2	41361833_Josephine_Robertson_A0A0B4J1V2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0485134	0.00824685	0.000000004125274	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0484994	0.00824686	0.000000004167747	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01705	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01705	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0531385	0.00912264	0.000000005834665	P01705	41361833_Josephine_Robertson_P01705_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0501145	0.00860439	0.000000005855611	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	LTA protein levels (SeqId = 3505-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LTA protein levels (SeqId = 3505-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lymphotoxin-alpha|Lymphotoxin-beta	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.8	0.137	0.0000000065	None	Gadd-DA_lta_protein_levels__seqid___3505-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0500517	0.00862755	0.000000006712756	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0475818	0.00824722	0.000000008114201	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0523984	0.00908373	0.000000008165459	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0494562	0.00861903	0.000000009767733	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04211	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04211	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0523157	0.00912367	0.000000009998717	P04211	41361833_Josephine_Robertson_P04211_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.049022	0.00860297	0.00000001233567	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0489891	0.00860483	0.00000001270613	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0468491	0.00824751	0.00000001369335	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0512356	0.00903915	0.00000001470398	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	CECR1 protein levels (SeqId = 6077-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CECR1 protein levels (SeqId = 6077-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adenosine deaminase 2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.78	0.137	0.000000015	None	Gadd-DA_cecr1_protein_levels__seqid___6077-63__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0484495	0.00860027	0.00000001798538	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	C1QC protein levels (SeqId = 14100-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C1QC protein levels (SeqId = 14100-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Complement C1q subcomponent subunit C	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.77	0.137	0.000000018	None	Gadd-DA_c1qc_protein_levels__seqid___14100-63__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0501937	0.00891358	0.00000001823066	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0461471	0.00824778	0.00000002244401	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0474882	0.00851683	0.00000002507253	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	FOLR2 protein levels (SeqId = 15587-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FOLR2 protein levels (SeqId = 15587-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Folate receptor beta	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.76	0.137	0.000000026	None	Gadd-DA_folr2_protein_levels__seqid___15587-20__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0476779	0.0085739	0.00000002731921	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.16846	0.0303325	0.000000028367	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.050502	0.00911429	0.00000003059902	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH29	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH29	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0503637	0.00911787	0.00000003377325	A0A0C4DH29	41361833_Josephine_Robertson_A0A0C4DH29_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04211	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04211	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0475094	0.00860849	0.00000003469231	P04211	41361833_Josephine_Robertson_P04211_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01705	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01705	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0475812	0.00863403	0.00000003630431	P01705	41361833_Josephine_Robertson_P01705_OSCA_model_3
Chung SA	-	26192630	2015-07-20	Autoantibody production in systemic lupus erythematosus	EFO_0004866, EFO_0002690	Replication	Table 2	DNA methylation	Autoantibody production in systemic lupus erythematosus	Technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	Wilcoxon rank sum test	140	1	46	Females	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-	-	0.000000039	-	26192630_autoantibody_production_in_systemic_lupus_erythematosus_replication
Gadd DA	Generation Scotland	35945220	31/07/2022	IFI16 protein levels (SeqId = 13940-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFI16 protein levels (SeqId = 13940-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-interferon-inducible protein 16	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.75	0.137	0.000000041	None	Gadd-DA_ifi16_protein_levels__seqid___13940-19__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.045171	0.00824814	0.00000004409344	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0451584	0.00824815	0.00000004447738	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0472131	0.00862874	0.00000004532708	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01705	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01705	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0469184	0.00860504	0.00000005048909	P01705	41361833_Josephine_Robertson_P01705_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0449683	0.00824822	0.0000000506451	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0496024	0.00912122	0.00000005470721	A0A0B4J1V2	41361833_Josephine_Robertson_A0A0B4J1V2_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04211	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04211	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0467008	0.00863319	0.00000006421049	P04211	41361833_Josephine_Robertson_P04211_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0444172	0.00824842	0.00000007358909	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_1
Chung SA	-	26192630	2015-07-20	Autoantibody production in systemic lupus erythematosus	EFO_0004866, EFO_0002690	Discovery	Table 2	DNA methylation	Autoantibody production in systemic lupus erythematosus	Technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	Wilcoxon rank sum test	186	1	46	Females	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-	-	0.000000087	-	26192630_autoantibody_production_in_systemic_lupus_erythematosus_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	SLAMF6 protein levels (SeqId = 5128-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SLAMF6 protein levels (SeqId = 5128-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SLAM family member 6	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.73	0.137	0.000000093	None	Gadd-DA_slamf6_protein_levels__seqid___5128-53__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0436877	0.00824869	0.0000001198665	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_1
Aslibekyan S	CHARGE	29617535	2018-04-04	Tumour necrosis factor-alpha	EFO_0003271	Meta-analysis base model	eTable 3	DNA methylation	Tumour necrosis factor-alpha	Age, sex, batch effects	Beta Values	pg/ml	Illumina HumanMethylation450	Whole blood	None	4163	5	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.009	0.002	0.00000013	None	29617535_Aslibekyan-S_tumour_necrosis_factor-alpha_meta-analysis_base_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02749	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02749	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0479945	0.00912594	0.0000001467782	P02749	41361833_Josephine_Robertson_P02749_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0433812	0.0082488	0.0000001467983	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0453173	0.00862051	0.0000001485421	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0452382	0.00860587	0.0000001487399	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0475725	0.00908284	0.0000001649087	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0451274	0.00861817	0.0000001660858	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0450134	0.00860893	0.0000001730638	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH29	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH29	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0430214	0.00824893	0.0000001859238	A0A0C4DH29	41361833_Josephine_Robertson_A0A0C4DH29_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TXNDC5 protein levels (SeqId = 11212-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXNDC5 protein levels (SeqId = 11212-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin domain-containing protein 5	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.711	0.137	0.00000021	None	Gadd-DA_txndc5_protein_levels__seqid___11212-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.044676	0.00860504	0.0000002110088	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_2
Aslibekyan S	CHARGE	29617535	2018-04-04	Tumour necrosis factor-alpha	EFO_0003271	Meta-analysis model 3	Table 2	DNA methylation	Tumour necrosis factor-alpha	Age, sex, batch effects, cell composition (reference based), smoking, body mass index	Beta Values	pg/ml	Illumina HumanMethylation450	Whole blood	Some associations replicated - see paper	4163	5	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.008	0.002	0.00000022	None	29617535_Aslibekyan-S_tumour_necrosis_factor-alpha_meta-analysis_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0445431	0.00860422	0.000000228601	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.164689	0.0318819	0.0000002423521	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Gadd DA	Generation Scotland	35945220	31/07/2022	CCL7 protein levels (SeqId = 4886-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCL7 protein levels (SeqId = 4886-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-C motif chemokine 7	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.7	0.136	0.00000025	None	Gadd-DA_ccl7_protein_levels__seqid___4886-3__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-1.842661	0.3577	0.000000259	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0423659	0.00824916	0.0000002845594	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0465366	0.00910651	0.0000003257694	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0464385	0.0090948	0.0000003330993	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0451989	0.00888296	0.0000003658205	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	ERO1L protein levels (SeqId = 7060-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ERO1L protein levels (SeqId = 7060-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ERO1-like protein alpha	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.69	0.137	0.00000039	None	Gadd-DA_ero1l_protein_levels__seqid___7060-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0435185	0.00859444	0.0000004164937	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0460721	0.00910581	0.0000004251413	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	CXCL13 protein levels (SeqId = 3487-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXCL13 protein levels (SeqId = 3487-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-X-C motif chemokine 13	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.69	0.137	0.00000044	None	Gadd-DA_cxcl13_protein_levels__seqid___3487-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RNASET2 protein levels (SeqId = 16913-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RNASET2 protein levels (SeqId = 16913-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribonuclease T2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.69	0.137	0.00000047	None	Gadd-DA_rnaset2_protein_levels__seqid___16913-8__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.041515	0.00824945	0.0000004899658	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0457219	0.00908592	0.0000004907107	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	UBLCP1 protein levels (SeqId = 19124-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBLCP1 protein levels (SeqId = 19124-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-like domain-containing CTD phosphatase 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.68	0.137	0.0000006	None	Gadd-DA_ublcp1_protein_levels__seqid___19124-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EPHB2 protein levels (SeqId = 8225-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPHB2 protein levels (SeqId = 8225-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ephrin type-B receptor 2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.68	0.137	0.00000061	None	Gadd-DA_ephb2_protein_levels__seqid___8225-86__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0424186	0.00850813	0.0000006245742	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0411176	0.00824959	0.0000006292865	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CD5L protein levels (SeqId = 3293-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD5L protein levels (SeqId = 3293-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: CD5 antigen-like	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.68	0.136	0.00000063	None	Gadd-DA_cd5l_protein_levels__seqid___3293-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01705	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01705	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0410586	0.00824961	0.0000006529712	P01705	41361833_Josephine_Robertson_P01705_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0409911	0.00824963	0.0000006811536	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0409561	0.00824964	0.000000696209	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0416464	0.00840482	0.0000007311174	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0424279	0.00859416	0.0000008027429	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Aslibekyan S	CHARGE	29617535	2018-04-04	Tumour necrosis factor-alpha	EFO_0003271	Meta-analysis model 2	eTable 3	DNA methylation	Tumour necrosis factor-alpha	Age, sex, batch effects, cell composition (reference based)	Beta Values	pg/ml	Illumina HumanMethylation450	Whole blood	None	4163	5	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.008	0.002	0.00000081	None	29617535_Aslibekyan-S_tumour_necrosis_factor-alpha_meta-analysis_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	SECTM1 protein levels (SeqId = 13093-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SECTM1 protein levels (SeqId = 13093-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Secreted and transmembrane protein 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.67	0.137	0.00000087	None	Gadd-DA_sectm1_protein_levels__seqid___13093-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0422958	0.00859977	0.0000008827038	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	IFNLR1 protein levels (SeqId = 7192-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFNLR1 protein levels (SeqId = 7192-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon lambda receptor 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.67	0.137	0.0000009	None	Gadd-DA_ifnlr1_protein_levels__seqid___7192-37__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH29	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH29	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0422065	0.00862772	0.000001008948	A0A0C4DH29	41361833_Josephine_Robertson_A0A0C4DH29_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0419943	0.00860933	0.000001084167	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0443625	0.00909737	0.000001091687	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_4
Colicino E	CHARGE	32697766	07-22-2020	All cause mortality	EFO_0004352	basic model	Table S2	All cause mortality	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	None	M values	Illumina HumanMethylation450	Whole blood	Effect estimates represent hazard ratio per 10% increase in DNA methylation.	12300	12	Adults	Both	European, African	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.92	None	0.0000011	None	32697766_Colicino-E_all_cause_mortality_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0418594	0.00860982	0.000001175168	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	IFI16 protein levels (SeqId = 12893-159)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFI16 protein levels (SeqId = 12893-159)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-interferon-inducible protein 16	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.66	0.136	0.0000012	None	Gadd-DA_ifi16_protein_levels__seqid___12893-159__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19827	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P19827	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0418253	0.00861377	0.000001212427	P19827	41361833_Josephine_Robertson_P19827_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0442245	0.00911816	0.00000124631	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH29	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH29	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0415303	0.00860366	0.000001399623	A0A0C4DH29	41361833_Josephine_Robertson_A0A0C4DH29_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0412581	0.00854922	0.000001407442	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0434588	0.00903568	0.000001526678	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19827	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P19827	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0415092	0.00864369	0.000001584397	P19827	41361833_Josephine_Robertson_P19827_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	GDNF protein levels (SeqId = 5822-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GDNF protein levels (SeqId = 5822-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glial cell line-derived neurotrophic factor	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.65	0.136	0.0000016	None	Gadd-DA_gdnf_protein_levels__seqid___5822-22__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19827	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P19827	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0437666	0.00913444	0.000001672592	P19827	41361833_Josephine_Robertson_P19827_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0394982	0.00825013	0.00000170442	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0394707	0.00825014	0.000001732948	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.025	0.00525	0.0000018	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	CCL8 protein levels (SeqId = 13748-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCL8 protein levels (SeqId = 13748-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-C motif chemokine 8	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.65	0.136	0.0000019	None	Gadd-DA_ccl8_protein_levels__seqid___13748-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NTRK2 protein levels (SeqId = 4866-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NTRK2 protein levels (SeqId = 4866-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BDNF/NT-3 growth factors receptor	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.65	0.137	0.0000019	None	Gadd-DA_ntrk2_protein_levels__seqid___4866-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CD8A protein levels (SeqId = 15462-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD8A protein levels (SeqId = 15462-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: T-cell surface glycoprotein CD8 alpha chain	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.65	0.137	0.000002	None	Gadd-DA_cd8a_protein_levels__seqid___15462-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04211	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04211	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0392136	0.00825022	0.000002022814	P04211	41361833_Josephine_Robertson_P04211_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0407435	0.00860505	0.000002212849	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 10613-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 10613-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.64	0.136	0.0000023	None	Gadd-DA_casc4_protein_levels__seqid___10613-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GRN protein levels (SeqId = 4992-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRN protein levels (SeqId = 4992-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Progranulin	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.65	0.137	0.0000024	None	Gadd-DA_grn_protein_levels__seqid___4992-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CD163 protein levels (SeqId = 5028-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD163 protein levels (SeqId = 5028-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Scavenger receptor cysteine-rich type 1 protein M130	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.64	0.137	0.0000024	None	Gadd-DA_cd163_protein_levels__seqid___5028-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CBLN4 protein levels (SeqId = 5688-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CBLN4 protein levels (SeqId = 5688-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cerebellin-4	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.64	0.137	0.0000028	None	Gadd-DA_cbln4_protein_levels__seqid___5688-65__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CXCL9 protein levels (SeqId = 9188-119)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXCL9 protein levels (SeqId = 9188-119)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-X-C motif chemokine 9	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.64	0.137	0.0000028	None	Gadd-DA_cxcl9_protein_levels__seqid___9188-119__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0404286	0.0086334	0.000002854984	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_3
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.00263	0.00056	0.000003	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0403341	0.00863524	0.000003025823	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0400288	0.00857439	0.000003062281	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0400308	0.00860522	0.000003317239	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PLOD3 protein levels (SeqId = 10612-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLOD3 protein levels (SeqId = 10612-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.63	0.137	0.0000039	None	Gadd-DA_plod3_protein_levels__seqid___10612-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LAP3 protein levels (SeqId = 13959-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LAP3 protein levels (SeqId = 13959-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytosol aminopeptidase	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.63	0.137	0.0000039	None	Gadd-DA_lap3_protein_levels__seqid___13959-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0394821	0.00855924	0.000004006372	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 8838-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 8838-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.63	0.14	0.0000042	None	Gadd-DA_casc4_protein_levels__seqid___8838-10__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.341679	0.0743	0.00000428	None	27105112_hiv_infection_cd4_tcells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.037903	0.00825064	0.000004385662	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Rheumatoid Arthritis (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Rheumatoid Arthritis (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18055	1	Adults (18-65y)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.052	0.0114	0.0000044	None	Robert-F-Hillary_Prevalent_Rheumatoid_Arthritis_(Self-report)_Basic_model
Liu C	CHARGE+	27843151	2016-12-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	European ancestry	Table S5	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g der day	Illumina HumanMethylation450	Whole blood	-	9643	10	64.2	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.00012886	2.81e-05	0.00000448	-	27843151_alcohol_consumption_per_day_european_ancestry
Gadd DA	Generation Scotland	35945220	31/07/2022	IL12B protein levels (SeqId = 10365-132)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL12B protein levels (SeqId = 10365-132)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-12 subunit beta|Interleukin-23 subunit alpha	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.628	0.137	0.0000045	None	Gadd-DA_il12b_protein_levels__seqid___10365-132__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0377576	0.00825068	0.000004771431	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0415144	0.00908868	0.00000497121	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_4
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	None	None	0.0000051	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	FCN3 protein levels (SeqId = 5462-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FCN3 protein levels (SeqId = 5462-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ficolin-3	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.62	0.137	0.0000054	None	Gadd-DA_fcn3_protein_levels__seqid___5462-62__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01743	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01743	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0414595	0.00911582	0.00000545717	P01743	41361833_Josephine_Robertson_P01743_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	sensitivity	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.14296	0.0315677	0.000005974017	None	39706196_Hannah-M.-Smith_glucose_sensitivity
Gadd DA	Generation Scotland	35945220	31/07/2022	LGALS9 protein levels (SeqId = 9197-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LGALS9 protein levels (SeqId = 9197-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Galectin-9	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.62	0.137	0.000006	None	Gadd-DA_lgals9_protein_levels__seqid___9197-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFRSF1B protein levels (SeqId = 3152-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFRSF1B protein levels (SeqId = 3152-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor receptor superfamily member 1B	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.62	0.137	0.0000063	None	Gadd-DA_tnfrsf1b_protein_levels__seqid___3152-57__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0389851	0.00863547	0.000006395238	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0386163	0.00857396	0.000006723186	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	GKN1 protein levels (SeqId = 15374-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GKN1 protein levels (SeqId = 15374-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gastrokine-1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.61	0.137	0.0000073	None	Gadd-DA_gkn1_protein_levels__seqid___15374-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DTX3L protein levels (SeqId = 11643-73)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DTX3L protein levels (SeqId = 11643-73)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase DTX3L	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.61	0.137	0.0000077	None	Gadd-DA_dtx3l_protein_levels__seqid___11643-73__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.038417	0.00858843	0.000007766821	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.02636	0.00574	0.0000079	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	LGALS7 protein levels (SeqId = 9196-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LGALS7 protein levels (SeqId = 9196-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Galectin-7	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.612	0.137	0.0000079	None	Gadd-DA_lgals7_protein_levels__seqid___9196-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL24 protein levels (SeqId = 3321-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL24 protein levels (SeqId = 3321-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-24	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.61	0.137	0.000008	None	Gadd-DA_il24_protein_levels__seqid___3321-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFRSF1B protein levels (SeqId = 8368-102)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFRSF1B protein levels (SeqId = 8368-102)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor receptor superfamily member 1B	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.61	0.137	0.0000081	None	Gadd-DA_tnfrsf1b_protein_levels__seqid___8368-102__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0403631	0.00905086	0.000008272946	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0367473	0.00825099	0.000008503435	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0366249	0.00825103	0.000009110851	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0400726	0.00903397	0.000009241226	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_4
Battram T	GEO	23334450	2020-09-15	Rheumatoid arthritis	EFO_0000685	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE42861	None	DNA methylation	Rheumatoid arthritis	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	689	1	Adults	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0203	0.00454	0.0000095	None	23334450_Battram-T_rheumatoid_arthritis_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse42861
Gadd DA	Generation Scotland	35945220	31/07/2022	XRCC6 protein levels (SeqId = 2835-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	XRCC6 protein levels (SeqId = 2835-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: X-ray repair cross-complementing protein 6	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.61	0.137	0.0000096	None	Gadd-DA_xrcc6_protein_levels__seqid___2835-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDK protein levels (SeqId = 2911-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDK protein levels (SeqId = 2911-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Midkine	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.61	0.137	0.0000098	None	Gadd-DA_mdk_protein_levels__seqid___2911-27__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0364014	0.0082511	0.00001032934	P01743	41361833_Josephine_Robertson_P01743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.036399	0.0082511	0.00001034308	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0379442	0.00860716	0.00001048522	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PROK1 protein levels (SeqId = 2247-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PROK1 protein levels (SeqId = 2247-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prokineticin-1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.6	0.137	0.000011	None	Gadd-DA_prok1_protein_levels__seqid___2247-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DSCAM protein levels (SeqId = 9175-48)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DSCAM protein levels (SeqId = 9175-48)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Down syndrome cell adhesion molecule	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.6	0.137	0.000011	None	Gadd-DA_dscam_protein_levels__seqid___9175-48__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL15RA protein levels (SeqId = 14054-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL15RA protein levels (SeqId = 14054-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-15 receptor subunit alpha	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.6	0.137	0.000011	None	Gadd-DA_il15ra_protein_levels__seqid___14054-17__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01743	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01743	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0378156	0.00862668	0.00001175665	P01743	41361833_Josephine_Robertson_P01743_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0399509	0.00911548	0.00001180042	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0376158	0.00859853	0.00001224531	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0374516	0.00857828	0.00001274875	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_3
Battram T	GEO	29921915	2020-09-15	Multiple sclerosis	EFO_0003885	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE106648	None	DNA methylation	Multiple sclerosis	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	279	1	Young adults	Both	Unclear	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0381	0.00859	0.000013	None	29921915_Battram-T_multiple_sclerosis_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse106648
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0374088	0.0086041	0.00001384456	P01743	41361833_Josephine_Robertson_P01743_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	IL6 protein levels (SeqId = 4673-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL6 protein levels (SeqId = 4673-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-6	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.59	0.137	0.000014	None	Gadd-DA_il6_protein_levels__seqid___4673-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LAIR2 protein levels (SeqId = 7130-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LAIR2 protein levels (SeqId = 7130-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leukocyte-associated immunoglobulin-like receptor 2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.592	0.137	0.000014	None	Gadd-DA_lair2_protein_levels__seqid___7130-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19827	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19827	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0358214	0.00825127	0.00001425784	P19827	41361833_Josephine_Robertson_P19827_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0392424	0.00905719	0.00001482499	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	VEGFA protein levels (SeqId = 2597-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VEGFA protein levels (SeqId = 2597-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vascular endothelial growth factor A	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.59	0.137	0.000015	None	Gadd-DA_vegfa_protein_levels__seqid___2597-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFSF8 protein levels (SeqId = 3421-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFSF8 protein levels (SeqId = 3421-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor ligand superfamily member 8	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.59	0.137	0.000015	None	Gadd-DA_tnfsf8_protein_levels__seqid___3421-54__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL12B protein levels (SeqId = 13733-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL12B protein levels (SeqId = 13733-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-12 subunit beta	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.59	0.137	0.000015	None	Gadd-DA_il12b_protein_levels__seqid___13733-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0372848	0.00861381	0.00001511269	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0392999	0.0091179	0.00001641789	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	LETMD1 protein levels (SeqId = 5751-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LETMD1 protein levels (SeqId = 5751-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: LETM1 domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.59	0.136	0.000017	None	Gadd-DA_letmd1_protein_levels__seqid___5751-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TACSTD2 protein levels (SeqId = 2619-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TACSTD2 protein levels (SeqId = 2619-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor-associated calcium signal transducer 2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.59	0.137	0.000017	None	Gadd-DA_tacstd2_protein_levels__seqid___2619-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFRSF4 protein levels (SeqId = 3730-81)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFRSF4 protein levels (SeqId = 3730-81)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor receptor superfamily member 4	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.59	0.137	0.000017	None	Gadd-DA_tnfrsf4_protein_levels__seqid___3730-81__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.036969	0.00859498	0.00001709527	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	ZNF526 protein levels (SeqId = 14619-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZNF526 protein levels (SeqId = 14619-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Zinc finger protein 526	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.59	0.137	0.000018	None	Gadd-DA_znf526_protein_levels__seqid___14619-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMA protein levels (SeqId = 3440-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMA protein levels (SeqId = 3440-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme A	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.59	0.137	0.000018	None	Gadd-DA_gzma_protein_levels__seqid___3440-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	OAZ1 protein levels (SeqId = 9893-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	OAZ1 protein levels (SeqId = 9893-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ornithine decarboxylase antizyme 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.59	0.137	0.000018	None	Gadd-DA_oaz1_protein_levels__seqid___9893-27__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02749	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02749	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0369158	0.00861265	0.0000182888	P02749	41361833_Josephine_Robertson_P02749_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0388422	0.00906521	0.00001841073	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	STX10 protein levels (SeqId = 12842-43)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STX10 protein levels (SeqId = 12842-43)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Syntaxin-10	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.59	0.137	0.000019	None	Gadd-DA_stx10_protein_levels__seqid___12842-43__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TAPBP protein levels (SeqId = 12378-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TAPBP protein levels (SeqId = 12378-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tapasin	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.58	0.137	0.00002	None	Gadd-DA_tapbp_protein_levels__seqid___12378-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ATAD1 protein levels (SeqId = 6625-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ATAD1 protein levels (SeqId = 6625-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ATPase family AAA domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.58	0.137	0.000022	None	Gadd-DA_atad1_protein_levels__seqid___6625-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TGFB1 protein levels (SeqId = 2333-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TGFB1 protein levels (SeqId = 2333-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transforming growth factor beta-1 proprotein	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.58	0.137	0.000022	None	Gadd-DA_tgfb1_protein_levels__seqid___2333-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CYB5R2 protein levels (SeqId = 19143-38)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CYB5R2 protein levels (SeqId = 19143-38)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NADH-cytochrome b5 reductase 2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.58	0.137	0.000022	None	Gadd-DA_cyb5r2_protein_levels__seqid___19143-38__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02749	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02749	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0365836	0.0086383	0.00002299002	P02749	41361833_Josephine_Robertson_P02749_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	HPSE protein levels (SeqId = 5604-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HPSE protein levels (SeqId = 5604-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heparanase	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.58	0.137	0.000023	None	Gadd-DA_hpse_protein_levels__seqid___5604-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MEPE protein levels (SeqId = 3209-69)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MEPE protein levels (SeqId = 3209-69)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Matrix extracellular phosphoglycoprotein	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.58	0.137	0.000023	None	Gadd-DA_mepe_protein_levels__seqid___3209-69__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CGB2 protein levels (SeqId = 6213-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CGB2 protein levels (SeqId = 6213-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Choriogonadotropin subunit beta variant 2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.579	0.137	0.000023	None	Gadd-DA_cgb2_protein_levels__seqid___6213-10__somascan_protein_measurement
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous decade consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	None	None	0.000023	None	31789449_Dugue-P-A_alcohol_consumption_previous_decade_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05160	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P05160	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0385548	0.00912768	0.0000241512	P05160	41361833_Josephine_Robertson_P05160_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM162A protein levels (SeqId = 6531-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM162A protein levels (SeqId = 6531-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM162A	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.137	0.000026	None	Gadd-DA_fam162a_protein_levels__seqid___6531-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJB14 protein levels (SeqId = 8053-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJB14 protein levels (SeqId = 8053-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily B member 14	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.58	0.137	0.000026	None	Gadd-DA_dnajb14_protein_levels__seqid___8053-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDK2 protein levels (SeqId = 12651-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDK2 protein levels (SeqId = 12651-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.58	0.137	0.000026	None	Gadd-DA_pdk2_protein_levels__seqid___12651-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PIK3R1 protein levels (SeqId = 8863-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIK3R1 protein levels (SeqId = 8863-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphatidylinositol 3-kinase regulatory subunit alpha	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.58	0.137	0.000026	None	Gadd-DA_pik3r1_protein_levels__seqid___8863-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IDUA protein levels (SeqId = 3169-70)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IDUA protein levels (SeqId = 3169-70)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-L-iduronidase	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.58	0.137	0.000027	None	Gadd-DA_idua_protein_levels__seqid___3169-70__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CTSA protein levels (SeqId = 3179-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CTSA protein levels (SeqId = 3179-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lysosomal protective protein	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.137	0.000028	None	Gadd-DA_ctsa_protein_levels__seqid___3179-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPT1 protein levels (SeqId = 9244-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPT1 protein levels (SeqId = 9244-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Palmitoyl-protein thioesterase 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.137	0.000028	None	Gadd-DA_ppt1_protein_levels__seqid___9244-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TMPRSS15 protein levels (SeqId = 3189-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMPRSS15 protein levels (SeqId = 3189-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Enteropeptidase	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.14	0.000028	None	Gadd-DA_tmprss15_protein_levels__seqid___3189-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CREG1 protein levels (SeqId = 9357-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CREG1 protein levels (SeqId = 9357-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CREG1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.137	0.000029	None	Gadd-DA_creg1_protein_levels__seqid___9357-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARPC3 protein levels (SeqId = 13573-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARPC3 protein levels (SeqId = 13573-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Actin-related protein 2/3 complex subunit 3	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.137	0.000029	None	Gadd-DA_arpc3_protein_levels__seqid___13573-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IFNL3 protein levels (SeqId = 5713-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFNL3 protein levels (SeqId = 5713-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon lambda-3	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.136	0.000031	None	Gadd-DA_ifnl3_protein_levels__seqid___5713-9__somascan_protein_measurement
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-	-	0.0000321	-	26500701_sex_kora_f4
Gadd DA	Generation Scotland	35945220	31/07/2022	KDELC2 protein levels (SeqId = 8296-117)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KDELC2 protein levels (SeqId = 8296-117)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein O-glucosyltransferase 3	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.137	0.000033	None	Gadd-DA_kdelc2_protein_levels__seqid___8296-117__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NXT1 protein levels (SeqId = 9942-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NXT1 protein levels (SeqId = 9942-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NTF2-related export protein 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.137	0.000033	None	Gadd-DA_nxt1_protein_levels__seqid___9942-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0372882	0.0089887	0.00003367902	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLGA7 protein levels (SeqId = 19174-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLGA7 protein levels (SeqId = 19174-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgin subfamily A member 7	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.567	0.137	0.000034	None	Gadd-DA_golga7_protein_levels__seqid___19174-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TMX3 protein levels (SeqId = 5654-70)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMX3 protein levels (SeqId = 5654-70)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein disulfide-isomerase TMX3	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.568	0.137	0.000034	None	Gadd-DA_tmx3_protein_levels__seqid___5654-70__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	WWOX protein levels (SeqId = 17724-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WWOX protein levels (SeqId = 17724-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: WW domain-containing oxidoreductase	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.56	0.136	0.000035	None	Gadd-DA_wwox_protein_levels__seqid___17724-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FOXM1 protein levels (SeqId = 10056-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FOXM1 protein levels (SeqId = 10056-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Forkhead box protein M1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.137	0.000035	None	Gadd-DA_foxm1_protein_levels__seqid___10056-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	JMJD6 protein levels (SeqId = 18322-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	JMJD6 protein levels (SeqId = 18322-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.137	0.000035	None	Gadd-DA_jmjd6_protein_levels__seqid___18322-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RBM39 protein levels (SeqId = 4284-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RBM39 protein levels (SeqId = 4284-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RNA-binding protein 39	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.137	0.000036	None	Gadd-DA_rbm39_protein_levels__seqid___4284-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARF5 protein levels (SeqId = 18409-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARF5 protein levels (SeqId = 18409-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor 5	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.57	0.137	0.000036	None	Gadd-DA_arf5_protein_levels__seqid___18409-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RNF43 protein levels (SeqId = 14120-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RNF43 protein levels (SeqId = 14120-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase RNF43	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.566	0.137	0.000036	None	Gadd-DA_rnf43_protein_levels__seqid___14120-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0374915	0.00907433	0.00003622539	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	LY9 protein levels (SeqId = 3324-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LY9 protein levels (SeqId = 3324-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: T-lymphocyte surface antigen Ly-9	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.56	0.137	0.000037	None	Gadd-DA_ly9_protein_levels__seqid___3324-51__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0354469	0.00859524	0.00003743649	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0340289	0.00825179	0.0000374694	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MYL6B protein levels (SeqId = 14227-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MYL6B protein levels (SeqId = 14227-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Myosin light chain 6B	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.56	0.137	0.000038	None	Gadd-DA_myl6b_protein_levels__seqid___14227-21__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0339932	0.0082518	0.00003817919	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0354363	0.00861762	0.00003942524	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	TPST2 protein levels (SeqId = 8024-64)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TPST2 protein levels (SeqId = 8024-64)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein-tyrosine sulfotransferase 2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.56	0.137	0.00004	None	Gadd-DA_tpst2_protein_levels__seqid___8024-64__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0352938	0.00862482	0.00004297322	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	TIMM21 protein levels (SeqId = 9058-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TIMM21 protein levels (SeqId = 9058-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitochondrial import inner membrane translocase subunit Tim21	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.56	0.137	0.000043	None	Gadd-DA_timm21_protein_levels__seqid___9058-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FUT8 protein levels (SeqId = 8244-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FUT8 protein levels (SeqId = 8244-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-(1,6)-fucosyltransferase	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.56	0.137	0.000043	None	Gadd-DA_fut8_protein_levels__seqid___8244-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0368012	0.00899733	0.00004332364	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	FCGR3B protein levels (SeqId = 3311-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FCGR3B protein levels (SeqId = 3311-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Low affinity immunoglobulin gamma Fc region receptor III-B	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.559	0.137	0.000044	None	Gadd-DA_fcgr3b_protein_levels__seqid___3311-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	XRCC4 protein levels (SeqId = 9886-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	XRCC4 protein levels (SeqId = 9886-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA repair protein XRCC4	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.56	0.137	0.000045	None	Gadd-DA_xrcc4_protein_levels__seqid___9886-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0369642	0.00906108	0.00004538295	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	DIMT1 protein levels (SeqId = 12694-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DIMT1 protein levels (SeqId = 12694-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable dimethyladenosine transferase	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.557	0.137	0.000047	None	Gadd-DA_dimt1_protein_levels__seqid___12694-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0335829	0.00825191	0.00004731812	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0343618	0.00844545	0.00004752786	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0350365	0.00861408	0.00004779846	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	SLC25A18 protein levels (SeqId = 5280-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SLC25A18 protein levels (SeqId = 5280-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitochondrial glutamate carrier 2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.56	0.137	0.000048	None	Gadd-DA_slc25a18_protein_levels__seqid___5280-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAP protein levels (SeqId = 5029-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAP protein levels (SeqId = 5029-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prolyl endopeptidase FAP	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.56	0.137	0.000049	None	Gadd-DA_fap_protein_levels__seqid___5029-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCL19 protein levels (SeqId = 4922-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCL19 protein levels (SeqId = 4922-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-C motif chemokine 19	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.56	0.14	0.00005	None	Gadd-DA_ccl19_protein_levels__seqid___4922-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXNB3 protein levels (SeqId = 16922-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXNB3 protein levels (SeqId = 16922-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-B3	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.55	0.137	0.000051	None	Gadd-DA_plxnb3_protein_levels__seqid___16922-53__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0347711	0.00858933	0.00005188409	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	NCK1 protein levels (SeqId = 5014-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NCK1 protein levels (SeqId = 5014-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytoplasmic protein NCK1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.55	0.137	0.000052	None	Gadd-DA_nck1_protein_levels__seqid___5014-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HLA-G protein levels (SeqId = 19636-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HLA-G protein levels (SeqId = 19636-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: HLA class I histocompatibility antigen, alpha chain G	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.555	0.137	0.000052	None	Gadd-DA_hla-g_protein_levels__seqid___19636-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFRSF17 protein levels (SeqId = 2665-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFRSF17 protein levels (SeqId = 2665-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor receptor superfamily member 17	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.55	0.137	0.000055	None	Gadd-DA_tnfrsf17_protein_levels__seqid___2665-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LILRB2 protein levels (SeqId = 5091-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LILRB2 protein levels (SeqId = 5091-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leukocyte immunoglobulin-like receptor subfamily B member 2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.55	0.137	0.000055	None	Gadd-DA_lilrb2_protein_levels__seqid___5091-28__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Kidney Disease (Estimated)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Kidney Disease (Estimated)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18318	1	Adults (18-65y)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.042	0.01033	0.000057	None	Robert-F-Hillary_Prevalent_Chronic_Kidney_Disease_(Estimated)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	ID2 protein levels (SeqId = 15403-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ID2 protein levels (SeqId = 15403-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA-binding protein inhibitor ID-2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.551	0.137	0.000057	None	Gadd-DA_id2_protein_levels__seqid___15403-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SUOX protein levels (SeqId = 18324-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SUOX protein levels (SeqId = 18324-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfite oxidase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.55	0.137	0.000058	None	Gadd-DA_suox_protein_levels__seqid___18324-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSP90B1 protein levels (SeqId = 6393-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSP90B1 protein levels (SeqId = 6393-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endoplasmin	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.55	0.137	0.00006	None	Gadd-DA_hsp90b1_protein_levels__seqid___6393-63__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SULT1E1 protein levels (SeqId = 16932-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SULT1E1 protein levels (SeqId = 16932-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Estrogen sulfotransferase	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.55	0.137	0.000061	None	Gadd-DA_sult1e1_protein_levels__seqid___16932-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02749	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02749	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0330757	0.00825205	0.00006149264	P02749	41361833_Josephine_Robertson_P02749_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0343843	0.0085846	0.00006223114	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPSS1 protein levels (SeqId = 14007-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPSS1 protein levels (SeqId = 14007-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.55	0.137	0.000063	None	Gadd-DA_papss1_protein_levels__seqid___14007-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SUB1 protein levels (SeqId = 19236-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SUB1 protein levels (SeqId = 19236-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Activated RNA polymerase II transcriptional coactivator p15	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.55	0.137	0.000063	None	Gadd-DA_sub1_protein_levels__seqid___19236-24__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0342758	0.00857826	0.00006482867	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	NPPB protein levels (SeqId = 3723-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NPPB protein levels (SeqId = 3723-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Natriuretic peptides B	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.136	0.000065	None	Gadd-DA_nppb_protein_levels__seqid___3723-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KIAA0319L protein levels (SeqId = 13698-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIAA0319L protein levels (SeqId = 13698-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dyslexia-associated protein KIAA0319-like protein	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.55	0.14	0.000066	None	Gadd-DA_kiaa0319l_protein_levels__seqid___13698-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0342807	0.00858905	0.00006605533	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	SH2D1A protein levels (SeqId = 4567-82)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH2D1A protein levels (SeqId = 4567-82)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SH2 domain-containing protein 1A	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.55	0.137	0.000067	None	Gadd-DA_sh2d1a_protein_levels__seqid___4567-82__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0342938	0.00861129	0.0000685453	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	SLAMF7 protein levels (SeqId = 5487-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SLAMF7 protein levels (SeqId = 5487-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SLAM family member 7	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000069	None	Gadd-DA_slamf7_protein_levels__seqid___5487-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0360739	0.00906937	0.00006996356	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	DDR1 protein levels (SeqId = 4122-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDR1 protein levels (SeqId = 4122-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Epithelial discoidin domain-containing receptor 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.136	0.00007	None	Gadd-DA_ddr1_protein_levels__seqid___4122-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FMOD protein levels (SeqId = 6367-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FMOD protein levels (SeqId = 6367-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibromodulin	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.54	0.137	0.000071	None	Gadd-DA_fmod_protein_levels__seqid___6367-66__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EFCAB14 protein levels (SeqId = 10830-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EFCAB14 protein levels (SeqId = 10830-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: EF-hand calcium-binding domain-containing protein 14	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000072	None	Gadd-DA_efcab14_protein_levels__seqid___10830-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0361899	0.00912281	0.00007313938	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.034144	0.00861237	0.00007388996	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK12 protein levels (SeqId = 5005-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK12 protein levels (SeqId = 5005-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 12	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000074	None	Gadd-DA_mapk12_protein_levels__seqid___5005-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDE1A protein levels (SeqId = 5253-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDE1A protein levels (SeqId = 5253-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000074	None	Gadd-DA_pde1a_protein_levels__seqid___5253-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EFNB3 protein levels (SeqId = 2514-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EFNB3 protein levels (SeqId = 2514-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ephrin-B3	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000074	None	Gadd-DA_efnb3_protein_levels__seqid___2514-65__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COL9A1 protein levels (SeqId = 6631-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COL9A1 protein levels (SeqId = 6631-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collagen alpha-1(IX) chain	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.542	0.137	0.000075	None	Gadd-DA_col9a1_protein_levels__seqid___6631-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MYL5 protein levels (SeqId = 19286-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MYL5 protein levels (SeqId = 19286-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Myosin light chain 5	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000076	None	Gadd-DA_myl5_protein_levels__seqid___19286-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACPP protein levels (SeqId = 19317-114)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACPP protein levels (SeqId = 19317-114)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prostatic acid phosphatase	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000076	None	Gadd-DA_acpp_protein_levels__seqid___19317-114__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZNF41 protein levels (SeqId = 10003-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZNF41 protein levels (SeqId = 10003-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Zinc finger protein 41	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000077	None	Gadd-DA_znf41_protein_levels__seqid___10003-15__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.0326194	0.00825218	0.00007759547	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GABARAPL1 protein levels (SeqId = 12661-44)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GABARAPL1 protein levels (SeqId = 12661-44)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-aminobutyric acid receptor-associated protein-like 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.541	0.137	0.000078	None	Gadd-DA_gabarapl1_protein_levels__seqid___12661-44__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF22 protein levels (SeqId = 9513-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF22 protein levels (SeqId = 9513-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 22	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.136	0.000079	None	Gadd-DA_fgf22_protein_levels__seqid___9513-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EGFL6 protein levels (SeqId = 17454-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EGFL6 protein levels (SeqId = 17454-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Epidermal growth factor-like protein 6	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000079	None	Gadd-DA_egfl6_protein_levels__seqid___17454-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SUN5 protein levels (SeqId = 11260-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SUN5 protein levels (SeqId = 11260-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SUN domain-containing protein 5	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.136	0.00008	None	Gadd-DA_sun5_protein_levels__seqid___11260-47__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Chronic Kidney Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Chronic Kidney Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18000	1	Adults (18-65y)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.013	0.00334	0.000081	None	Robert-F-Hillary_Incident_Chronic_Kidney_Disease_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	ANGPT4 protein levels (SeqId = 2500-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANGPT4 protein levels (SeqId = 2500-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Angiopoietin-4	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000081	None	Gadd-DA_angpt4_protein_levels__seqid___2500-2__somascan_protein_measurement
Cardenas A	Project Viva	31300640	Jul 12, 2019	fractional exhaled nitric oxide (FeNO)	EFO_0005536	None	Supplementary Data 2	DNA methylation	fractional exhaled nitric oxide (FeNO)	Age, Sex, Smoking, Cell composition (reference free), Batch effects, Ancestry (other), Body mass index, Education, sine and cosine of season at sample collection	Beta values	ppb	Illumina HumanMethylationEPIC	nasal epithelium	None	517	1	Children	Both	Other	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-2.31	0.581	0.000081	SE manually calculated	31300640_Cardenas-A_fractional_exhaled_nitric_oxide__feno_
Gadd DA	Generation Scotland	35945220	31/07/2022	CHEK2 protein levels (SeqId = 19328-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHEK2 protein levels (SeqId = 19328-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase Chk2	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000084	None	Gadd-DA_chek2_protein_levels__seqid___19328-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PACAP protein levels (SeqId = 16322-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PACAP protein levels (SeqId = 16322-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Marginal zone B- and B1-cell-specific protein	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.53	0.136	0.000085	None	Gadd-DA_pacap_protein_levels__seqid___16322-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSMB3 protein levels (SeqId = 18339-207)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSMB3 protein levels (SeqId = 18339-207)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteasome subunit beta type-3	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.14	0.000086	None	Gadd-DA_psmb3_protein_levels__seqid___18339-207__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSPB1 protein levels (SeqId = 11103-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSPB1 protein levels (SeqId = 11103-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heat shock protein beta-1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.537	0.137	0.000087	None	Gadd-DA_hspb1_protein_levels__seqid___11103-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MMP1 protein levels (SeqId = 4924-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MMP1 protein levels (SeqId = 4924-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interstitial collagenase	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000089	None	Gadd-DA_mmp1_protein_levels__seqid___4924-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF4 protein levels (SeqId = 4123-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF4 protein levels (SeqId = 4123-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 4	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.528	0.135	0.000091	None	Gadd-DA_fgf4_protein_levels__seqid___4123-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EXOSC1 protein levels (SeqId = 7930-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EXOSC1 protein levels (SeqId = 7930-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Exosome complex component CSL4	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000091	None	Gadd-DA_exosc1_protein_levels__seqid___7930-3__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age*sex	PATO_0000047,EFO_0000246	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	age*sex	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.00097	0.00025	0.000092	None	33450751_Mulder-RH_age_sex_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	NXF1 protein levels (SeqId = 12453-161)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NXF1 protein levels (SeqId = 12453-161)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear RNA export factor 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.54	0.137	0.000093	None	Gadd-DA_nxf1_protein_levels__seqid___12453-161__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TXNL4B protein levels (SeqId = 15316-262)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXNL4B protein levels (SeqId = 15316-262)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin-like protein 4B	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.53	0.137	0.000094	None	Gadd-DA_txnl4b_protein_levels__seqid___15316-262__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VCAM1 protein levels (SeqId = 2967-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VCAM1 protein levels (SeqId = 2967-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vascular cell adhesion protein 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.53	0.137	0.000095	None	Gadd-DA_vcam1_protein_levels__seqid___2967-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SUSD1 protein levels (SeqId = 9582-93)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SUSD1 protein levels (SeqId = 9582-93)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sushi domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	-0.534	0.137	0.000098	None	Gadd-DA_susd1_protein_levels__seqid___9582-93__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0321494	0.0082523	0.00009830563	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08122652	chr3:122281939	3	122281939	PARP9;DTX3L	North shore	0.0335487	0.00861569	0.00009908112	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_2