author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.18125	0.00467	3.8e-93	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.152731	0.0081597	2.814758e-77	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.138156	0.00817739	1.9510789999999998e-63	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.107449	0.00820877	6.243865e-39	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0877236	0.00822474	1.839064e-26	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0791468	0.00823067	7.931599000000001e-22	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.07645	0.00823241	1.814856e-20	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0656398	0.00823877	0.000000000000001741942	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.00115597	0.00014627	0.00000000000000676	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-	-	0.00000000000025	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0594701	0.00824196	0.0000000000005635596	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.057516	0.0082429	0.000000000003130472	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0573124	0.008243	0.000000000003730879	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0560391	0.0082436	0.00000000001102555	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0553423	0.00824392	0.00000000001975159	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Petersen A-K	KORA F4	24014485	2013-09-06	M35718_dihomo-linolenate_20:3n3_or_n6	EFO_0004727, EFO_0004725	no snps model	Table S2	M35718_dihomo-linolenate_20:3n3_or_n6	DNA methylation	Age, sex, body mass index, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1760	1	Adults	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.76	0.098	0.0000000003	None	24014485_Petersen-A-K_m35718_dihomo-linolenate_20_3n3_or_n6_no_snps_model
Petersen A-K	KORA F4	24014485	2013-09-06	M35718_dihomo-linolenate_20:3n3_or_n6	EFO_0004727, EFO_0004725	snps as covariates model	Table S4	M35718_dihomo-linolenate_20:3n3_or_n6	DNA methylation	Age, sex, body mass index, cell composition (reference based), genotype	None	Beta Values	Illumina HumanMethylation450	Whole blood	used three nearby snps as covariates	1760	1	Adults	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.76	0.099	0.00000000046	None	24014485_Petersen-A-K_m35718_dihomo-linolenate_20_3n3_or_n6_snps_as_covariates_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0513535	0.00824568	0.000000000485537	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0488618	0.00824671	0.000000003192757	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0487663	0.00824675	0.000000003425592	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0049	0.00077	0.0000000039	None	33564054_Kashima-K_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0478601	0.00824711	0.000000006638357	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0478566	0.00824711	0.00000000665511	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0473899	0.00824729	0.000000009313068	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0463817	0.00824769	0.00000001904244	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0454415	0.00824804	0.0000000366182	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.044009	0.00824857	0.00000009677815	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.00044225	8.58e-05	0.000000301	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0405282	0.00824979	0.0000009083159	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0401967	0.0082499	0.000001114107	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0400253	0.00824996	0.000001237417	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0400216	0.00824996	0.000001240252	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0395492	0.00825011	0.000001652763	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.039346	0.00825018	0.000001868223	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0390898	0.00825026	0.000002178467	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0377887	0.00825067	0.000004686372	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0371925	0.00825086	0.000006603935	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-0.0370504	0.0082509	0.00000716113	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.172791	0.0387922	0.000008470197	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0362975	0.00825113	0.0000109467	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.035986	0.00825122	0.00001301765	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	-	-	0.0000257	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0329797	0.00825208	0.00006459072	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.152272	0.038547	0.00007836823	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10266490	chr1:55013709	1	55013709	ACOT11	Open sea	0.0323275	0.00825226	0.00008991148	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_1