author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.014	0.00033	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.058	0.0012	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.31969	0.00577	2.1e-120	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	3.01266	0.08928	9.359999999999999e-52	-	25282492_fetal_vs_adult_liver
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-	-	1.3399999999999998e-34	-	26857698_primary_sjogrens_syndrome_whole_blood
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2468351 (gene symbol: RSAD2)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2468351 (gene symbol: RSAD2)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	None	None	2.9e-34	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2468351__gene_symbol__rsad2__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0965254	0.0099502	3.486841e-22	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0688227	0.00823699	7.105465e-17	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Chung SA	-	26192630	2015-07-20	Autoantibody production in systemic lupus erythematosus	EFO_0004866, EFO_0002690	Combined	Table S1	DNA methylation	Autoantibody production in systemic lupus erythematosus	Age, disease duration, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	Wilcoxon rank sum test	326	2	46	Females	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-	-	4.4e-16	-	26192630_autoantibody_production_in_systemic_lupus_erythematosus_combined
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0803354	0.0100119	0.00000000000000110062	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_4
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	CD19+ B cells	Table S6	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	CD19+ B cells	-	71	1	-	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-	-	0.000000000000003	-	26857698_primary_sjogrens_syndrome_cd19_b_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0674399	0.00855912	0.000000000000003522298	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0669421	0.00856144	0.000000000000005684511	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0647394	0.00855857	0.00000000000004131632	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0639099	0.00850851	0.00000000000006192316	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_3
Chung SA	-	26192630	2015-07-20	Autoantibody production in systemic lupus erythematosus	EFO_0004866, EFO_0002690	Linear regression model	Table 2	DNA methylation	Autoantibody production in systemic lupus erythematosus	Age, ethnicity, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	-	326	2	46	Females	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.052	0.0071	0.00000000000032	-	26192630_autoantibody_production_in_systemic_lupus_erythematosus_linear_regression_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0543127	0.00824438	0.00000000004614678	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Chung SA	-	26192630	2015-07-20	Autoantibody production in systemic lupus erythematosus	EFO_0004866, EFO_0002690	Discovery	Table 2	DNA methylation	Autoantibody production in systemic lupus erythematosus	Technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	Wilcoxon rank sum test	186	1	46	Females	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-	-	0.00000000021	-	26192630_autoantibody_production_in_systemic_lupus_erythematosus_discovery
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.00073115	0.00011497	0.000000000302	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0491744	0.00824658	0.000000002533353	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.00711	0.00125	0.000000014	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.055781	0.0100237	0.00000002668856	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0437933	0.00824865	0.0000001117455	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0427272	0.00824903	0.0000002252375	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Chung SA	-	26192630	2015-07-20	Autoantibody production in systemic lupus erythematosus	EFO_0004866, EFO_0002690	Replication	Table 2	DNA methylation	Autoantibody production in systemic lupus erythematosus	Technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	Wilcoxon rank sum test	140	1	46	Females	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-	-	0.00000034	-	26192630_autoantibody_production_in_systemic_lupus_erythematosus_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.049723	0.00998449	0.0000006430112	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	MX1 protein levels (SeqId = 17460-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MX1 protein levels (SeqId = 17460-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon-induced GTP-binding protein Mx1	774	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.7	0.144	0.0000013	None	Gadd-DA_mx1_protein_levels__seqid___17460-51__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.040743	0.0085495	0.000001901521	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0474109	0.00998452	0.000002069353	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_4
Mok A	-	28074145	2016-12-07	Lupus nephritis vs lupus without nephritis	EFO_0005761	Discovery	Table 2	DNA methylation	Lupus nephritis vs lupus without nephritis	Disease duration and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	322	1	45.5	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.054	0.0114	0.00000211	-	28074145_lupus_nephritis_vs_lupus_without_nephritis_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0403924	0.00856782	0.000002446131	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_3
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0005671, EFO_0004318	Former vs never smoking	Table S5	DNA methylation	Former versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	13474	16	62.9	Both	European,African	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0043	9e-04	0.0000029	-	27651444_smoking_former_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.038503	0.00825045	0.000003086662	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0398746	0.00855677	0.00000318988	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0383657	0.00825049	0.000003346564	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0395876	0.008536	0.000003553057	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0397908	0.00858548	0.000003606101	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0373879	0.00840453	0.000008709081	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.044214	0.00995256	0.0000089582	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0380803	0.00858198	0.000009178693	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0378872	0.00858318	0.00001021444	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0360568	0.0082512	0.00001251649	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0360202	0.00825121	0.00001277354	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0370381	0.00849718	0.00001316268	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0435692	0.0100336	0.00001419286	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0361706	0.00833785	0.00001446674	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0368832	0.00852913	0.00001539761	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Rheumatoid Arthritis (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Rheumatoid Arthritis (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18055	1	Adults (18-65y)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.045	0.0104	0.000016	None	Robert-F-Hillary_Prevalent_Rheumatoid_Arthritis_(Self-report)_Basic_model
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0006	0.00014	0.000018	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0366833	0.00856029	0.00001836661	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0352866	0.00825143	0.00001911218	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0347921	0.00825157	0.00002496923	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.035654	0.00849625	0.00002727476	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0360117	0.00858731	0.00002761833	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0358494	0.00857648	0.00002932445	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0399873	0.00958973	0.0000306612	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0354396	0.00856753	0.00003545971	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.035414	0.00857743	0.00003667716	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0413075	0.0100277	0.00003820554	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0351185	0.0085826	0.00004302812	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0337364	0.00825187	0.00004368074	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0335939	0.00825191	0.00004704832	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0335415	0.00825193	0.00004834885	A0A0B4J1V2	41361833_Josephine_Robertson_A0A0B4J1V2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0344413	0.00855607	0.00005717187	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	ISG15 protein levels (SeqId = 14151-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ISG15 protein levels (SeqId = 14151-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-like protein ISG15	774	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.58	0.144	0.000059	None	Gadd-DA_isg15_protein_levels__seqid___14151-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0391088	0.00975503	0.00006125531	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0342716	0.00857632	0.00006471813	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0387216	0.00969224	0.00006497934	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01705	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01705	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0401787	0.0100613	0.00006545066	P01705	41361833_Josephine_Robertson_P01705_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0400438	0.0100435	0.00006723281	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	FTH1 protein levels (SeqId = 5934-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FTH1 protein levels (SeqId = 5934-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ferritin heavy chain|Ferritin light chain	774	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.57	0.144	0.000072	None	Gadd-DA_fth1_protein_levels__seqid___5934-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0394261	0.00996181	0.00007602295	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	FTL protein levels (SeqId = 15324-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FTL protein levels (SeqId = 15324-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ferritin light chain	774	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.57	0.144	0.000077	None	Gadd-DA_ftl_protein_levels__seqid___15324-58__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0396473	0.0100481	0.00007992327	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	-0.0390425	0.00994434	0.00008672944	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10959651	chr2:7018020	2	7018020	RSAD2	Open sea	0.0391292	0.0100322	0.00009648412	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_4