author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	0.17993	0.00339	3.7e-117	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	CRELD1 protein levels (SeqId = 7628-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRELD1 protein levels (SeqId = 7628-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cysteine-rich with EGF-like domain protein 1	774	1	Adults (18-65 years)	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-1.01	0.093	2.3e-27	None	Gadd-DA_creld1_protein_levels__seqid___7628-40__somascan_protein_measurement
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2610241 (gene symbol: FANCD2)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2610241 (gene symbol: FANCD2)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg12395284	chr3:10153222	3	10153222	-	North shelf	None	None	0.0000000000000074	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2610241__gene_symbol__fancd2__meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	0.0016	None	0.00000000056	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	0.83	0.136	0.0000000008	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	0.023	0.00393	0.0000000082	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.0943178	0.0186284	0.0000004164532	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	0.0957758	0.0191883	0.000000605321	None	39706196_Hannah-M.-Smith_bmi_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.00079	0.00017	0.0000017	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	0.0918074	0.0192334	0.000001826766	None	39706196_Hannah-M.-Smith_body_fat_discovery
Battram T	ARIES	None	2020-08-20	Free cholesterol in very large HDL	EFO_0008591	None	None	DNA methylation	Free cholesterol in very large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	684	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-4.8	1.03	0.0000049	None	Battram-T_free_cholesterol_in_very_large_hdl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	0.0400123	0.00878791	0.000005328662	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.0375207	0.00825076	0.000005471031	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	ARIES	None	2020-08-20	Total lipids in very large HDL	EFO_0004529	None	None	DNA methylation	Total lipids in very large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.61	0.133	0.0000057	None	Battram-T_total_lipids_in_very_large_hdl
Battram T	ARIES	None	2020-08-20	Total cholesterol in very large HDL	EFO_0004574	None	None	DNA methylation	Total cholesterol in very large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	683	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-1.28	0.28	0.000006	None	Battram-T_total_cholesterol_in_very_large_hdl
Battram T	ARIES	None	2020-08-20	Cholesterol esters in very large HDL	EFO_0008589	None	None	DNA methylation	Cholesterol esters in very large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	682	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-1.71	0.38	0.0000088	None	Battram-T_cholesterol_esters_in_very_large_hdl
Battram T	ARIES	None	2020-08-20	Concentration of very large HDL particles	EFO_0004612	None	None	DNA methylation	Concentration of very large HDL particles	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	None	None	0.00001	None	Battram-T_concentration_of_very_large_hdl_particles
Battram T	ARIES	None	2020-08-20	Mean diameter for HDL particles	EFO_0008592	None	None	DNA methylation	Mean diameter for HDL particles	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	nm	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.58	0.132	0.000012	None	Battram-T_mean_diameter_for_hdl_particles
Battram T	ARIES	None	2020-08-20	HDL cholesterol	EFO_0004612	fasting	None	DNA methylation	HDL cholesterol	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	691	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.35	0.082	0.000019	None	Battram-T_hdl_cholesterol_fasting
Battram T	ARIES	None	2020-08-20	Total cholesterol in HDL2	EFO_0004574	None	None	DNA methylation	Total cholesterol in HDL2	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	684	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.45	0.105	0.000022	None	Battram-T_total_cholesterol_in_hdl2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	0.0371962	0.00880012	0.00002384935	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Phospholipids in very large HDL	EFO_0004639	None	None	DNA methylation	Phospholipids in very large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	683	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-1.1	0.26	0.000028	None	Battram-T_phospholipids_in_very_large_hdl
Battram T	ARIES	None	2020-08-20	Free cholesterol in large HDL	EFO_0008591	None	None	DNA methylation	Free cholesterol in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-2.9	0.69	0.000028	None	Battram-T_free_cholesterol_in_large_hdl
Battram T	ARIES	None	2020-08-20	Cholesterol esters in large HDL	EFO_0008589	None	None	DNA methylation	Cholesterol esters in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	684	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.9	0.214	0.000031	None	Battram-T_cholesterol_esters_in_large_hdl
Battram T	ARIES	None	2020-08-20	Total cholesterol in large HDL	EFO_0004574	None	None	DNA methylation	Total cholesterol in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.68	0.163	0.000033	None	Battram-T_total_cholesterol_in_large_hdl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.0331684	0.00825203	0.00005863151	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	ARIES	None	2020-08-20	Total lipids in large HDL	EFO_0004529	None	None	DNA methylation	Total lipids in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.36	0.089	0.000071	None	Battram-T_total_lipids_in_large_hdl
Battram T	ARIES	None	2020-08-20	Concentration of large HDL particles	EFO_0004612	None	None	DNA methylation	Concentration of large HDL particles	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	None	None	0.000078	None	Battram-T_concentration_of_large_hdl_particles
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12395284	chr3:10153222	3	10153222	-	North shelf	-0.0325867	0.00825219	0.0000788908	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
