author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	0.141899	0.00816841	6.320122e-67	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	0.143124	0.00824511	7.908961e-67	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	0.141607	0.00817337	1.389555e-66	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	0.140233	0.00819442	5.059759e-65	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	-0.11545	0.00616	2.3e-45	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	NRXN1 protein levels (SeqId = 8971-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NRXN1 protein levels (SeqId = 8971-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Neurexin-1	774	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	1.19	0.091	6.2e-39	None	Gadd-DA_nrxn1_protein_levels__seqid___8971-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL26 protein levels (SeqId = 16760-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL26 protein levels (SeqId = 16760-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-26	774	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	1.17	0.091	2.1e-37	None	Gadd-DA_il26_protein_levels__seqid___16760-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COPS7B protein levels (SeqId = 12384-92)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COPS7B protein levels (SeqId = 12384-92)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: COP9 signalosome complex subunit 7b	774	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	1.16	0.091	4.4e-37	None	Gadd-DA_cops7b_protein_levels__seqid___12384-92__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HDGFRP3 protein levels (SeqId = 18899-82)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDGFRP3 protein levels (SeqId = 18899-82)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatoma-derived growth factor-related protein 3	774	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	0.81	0.092	1.5e-18	None	Gadd-DA_hdgfrp3_protein_levels__seqid___18899-82__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSF3 protein levels (SeqId = 4840-73)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSF3 protein levels (SeqId = 4840-73)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granulocyte colony-stimulating factor	774	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	0.638	0.092	0.0000000000035	None	Gadd-DA_csf3_protein_levels__seqid___4840-73__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	0.0024	None	0.00000000017	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Walker R	Generation Scotland	33397400	2021-01-04	APOE e2 vs e4	EFO_0007659	Meta-analysis	Table 1	DNA methylation	APOE e2 vs e4	age, sex, smoking, cell composition (reference based), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	3587	1	Adults	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	-0.046	0.008	0.0000000058	Effect direction is relative to carriers of the e2 allele	33397400_Walker-R_apoe_e2_vs_e4_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	-0.0411447	0.00817369	0.0000004865683	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	-0.0392691	0.00814624	0.000001446189	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	-0.038239	0.00808621	0.000002278231	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	LRRTM4 protein levels (SeqId = 6572-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LRRTM4 protein levels (SeqId = 6572-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leucine-rich repeat transmembrane neuronal protein 4	774	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	0.433	0.092	0.0000023	None	Gadd-DA_lrrtm4_protein_levels__seqid___6572-10__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	-0.0011	0.00024	0.0000036	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	0.0337844	0.00825186	0.00004259815	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13119609	chr19:45449297	19	45449297	APOC2	Open sea	-0.0332793	0.008252	0.0000553757	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
