author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0058	0.00027	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.018	0.0018	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	1.05819	0.0349786	3.398664e-196	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	1.00239	0.0333759	1.8270649999999998e-193	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.6523	0.00568	1.4e-179	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.716038	0.0349305	2.743725e-92	None	39706196_Hannah-M.-Smith_bmi_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.744511	0.0364092	7.577362e-92	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.166093	0.00814189	3.0852829999999996e-91	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.22375	0.011203	1.395003e-87	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.160448	0.0081496	3.439087e-85	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.158727	0.0081519	2.16989e-83	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.217627	0.01122	9.008169e-83	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.218073	0.0112463	1.0033160000000001e-82	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.707788	0.0366931	4.800464e-82	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.675807	0.0350586	6.116404e-82	None	39706196_Hannah-M.-Smith_body_fat_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.684126	0.0355945	1.610811e-81	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.150004	0.00816315	1.409317e-74	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.660008	0.0366086	5.291959e-72	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.626544	0.035002	5.13071e-71	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-4.4	0.249	2.1e-69	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.584746	0.0337738	1.264931e-66	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.213846	0.0125447	1.5488679999999998e-64	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.209891	0.0124386	2.7616189999999997e-63	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.133076	0.00818314	5.998774e-59	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.189905	0.0118833	5.268635e-57	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.128907	0.00818768	2.144284e-55	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.25	0.0159	1.7e-54	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.163994	0.010897	8.347314e-51	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.16718	0.0112908	3.002768e-49	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.161905	0.0109872	8.479644e-49	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.191046	0.0131846	2.969729e-47	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.117604	0.00819928	2.417029e-46	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.114878	0.00820191	2.7506139999999996e-44	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.156716	0.011259	9.185202999999999e-44	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0007165	5.21e-05	5.47e-43	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.153988	0.0112069	1.0678e-42	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0006171	4.51e-05	1.17e-42	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.150838	0.0114715	2.880079e-39	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.146471	0.011329	4.99199e-38	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.105496	0.0082105	1.3906799999999998e-37	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.133687	0.0104099	1.512307e-37	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.102049	0.00821347	2.890741e-35	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.101691	0.00821377	4.981446e-35	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.138804	0.0113362	2.6490569999999998e-34	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.135468	0.0113351	9.085285000000001e-33	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0979732	0.00821685	1.2639150000000002e-32	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0961839	0.00821829	1.685595e-31	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0006421	5.53e-05	3.23e-31	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0005442	4.77e-05	3.38e-30	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14350	1	Adults (18-65y)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.19	0.017	4.3000000000000004e-30	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.146002	0.012813	5.936826e-30	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Ischemic Heart Disease (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Ischemic Heart Disease (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18059	1	Adults (18-65y)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.19	0.0171	1.6000000000000001e-28	None	Robert-F-Hillary_Prevalent_Ischemic_Heart_Disease_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.123763	0.0112474	4.720868000000001e-28	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0902265	0.0082229	6.644931e-28	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0888975	0.00822388	3.920018e-27	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0881769	0.00822441	1.014849e-26	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.120385	0.0113389	3.0931679999999997e-26	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Ochoa-Rosales C	ESTHER, KORA-F4 , LOLIPOP, SHIP-Trend	32033992	2020-04-01	Statin use	GO_0036273	Discovery	Table 1	Statin use	DNA methylation	sex, age, smoking, body mass index, systolic blood pressure, antihypertensive medication, coronary heart disease, type 2 diabetes, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	Some cohorts used the Illumina HumanMethylationEPIC, but results were restricted to sites measured by the HM450	6820	4	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0219	0.0021	1.0999999999999999e-25	None	32033992_Ochoa-Rosales-C_statin_use_discovery
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	1.39388	0.09679	9.48e-25	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.11455	0.0111637	1.280005e-24	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0842605	0.00822721	1.5598359999999999e-24	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.114982	0.0113338	4.187655e-24	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.121839	0.012096	8.724023e-24	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.073	0.00722	9.3e-24	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2413907 (gene symbol: DHCR24)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2413907 (gene symbol: DHCR24)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	None	None	1.1e-22	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2413907__gene_symbol__dhcr24__meta-analysis
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Ischemic Heart Disease (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Ischemic Heart Disease (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14391	1	Adults (18-65y)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.18	0.0184	1.8e-21	None	Robert-F-Hillary_Prevalent_Ischemic_Heart_Disease_(Self-report)_Fully-adjusted_model
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery	Table S5	DNA methylation	Serum triglycerides	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0185676	0.0019627	3.0700000000000002e-21	-	28213390_serum_triglycerides_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.119643	0.0127651	8.08822e-21	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.103423	0.0113428	8.630687999999999e-20	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.115563	0.0127923	1.8615509999999999e-19	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_4
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-	-	3.7e-19	-	28002404_body_mass_index_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0997576	0.0113021	1.200456e-18	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0996456	0.0113703	2.093971e-18	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_2
Petersen A-K	KORA F4	24014485	2013-09-06	M32492_caprylate_8:0	EFO_0004727, EFO_0004725	no snps model	Table S2	M32492_caprylate_8:0	DNA methylation	Age, sex, body mass index, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1760	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	3.9	0.078	2.7e-18	None	24014485_Petersen-A-K_m32492_caprylate_8_0_no_snps_model
Petersen A-K	KORA F4	24014485	2013-09-06	M32492_caprylate_8:0	EFO_0004727, EFO_0004725	snps as covariates model	Table S4	M32492_caprylate_8:0	DNA methylation	Age, sex, body mass index, cell composition (reference based), genotype	None	Beta Values	Illumina HumanMethylation450	Whole blood	used three nearby snps as covariates	1760	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	4	0.08	3.6e-18	None	24014485_Petersen-A-K_m32492_caprylate_8_0_snps_as_covariates_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0715495	0.00823541	4.072844e-18	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.109099	0.01292	3.347584e-17	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.11022	0.0130638	3.5569590000000004e-17	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0954869	0.0113975	5.87442e-17	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.108729	0.0130768	1.000865e-16	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0948522	0.0114319	1.158226e-16	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0681713	0.00823736	1.384279e-16	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0680703	0.00823742	1.53415e-16	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0680458	0.00823743	1.572997e-16	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0928058	0.0113256	2.726046e-16	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	sensitivity	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.298067	0.0366876	4.783784e-16	None	39706196_Hannah-M.-Smith_glucose_sensitivity
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.00153625	0.00018637	4.9e-16	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0666822	0.00823819	6.210469e-16	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0851779	0.0105639	8.007222e-16	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0902608	0.0112589	0.00000000000000116623	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.103983	0.0130431	0.000000000000001672657	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0643546	0.00823946	0.000000000000006078775	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0869066	0.0111509	0.000000000000006942691	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0881469	0.0113721	0.000000000000009704695	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication	Table S5	DNA methylation	Serum triglycerides	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	4261	5	65	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0108879	0.001426	0.0000000000000226	-	28213390_serum_triglycerides_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0967362	0.0127591	0.0000000000000361369	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0861232	0.0113775	0.00000000000003966089	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery adjusted for BMI	Table S9	DNA methylation	Serum triglycerides	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0151417	0.0020287	0.000000000000084	-	28213390_serum_triglycerides_discovery_adjusted_for_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0974653	0.0131176	0.0000000000001145089	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0972116	0.0131471	0.0000000000001500509	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.084209	0.0114175	0.0000000000001725563	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Stroke (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Stroke (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18056	1	Adults (18-65y)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.087	0.01184	0.00000000000023	None	Robert-F-Hillary_Prevalent_Stroke_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0808898	0.0111	0.00000000000033217	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0596093	0.00824189	0.0000000000004977077	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0803644	0.0113505	0.000000000001504359	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0790198	0.0111662	0.000000000001543021	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0582959	0.00824253	0.000000000001589592	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-	-	0.00000000000287	-	28095459_body_mass_index_metaanalysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0793134	0.0113723	0.000000000003206351	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Walker R	Generation Scotland	33397400	2021-01-04	APOE e2 vs e4	EFO_0007659	Meta-analysis	Table 1	DNA methylation	APOE e2 vs e4	age, sex, smoking, cell composition (reference based), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	3587	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.04	0.0058	0.0000000000036	Effect direction is relative to carriers of the e2 allele	33397400_Walker-R_apoe_e2_vs_e4_meta-analysis
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-	-	0.00000000000447	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0570351	0.00824313	0.00000000000473321	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0567777	0.00824325	0.000000000005897575	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0781123	0.0113504	0.000000000006146423	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0771567	0.0113506	0.00000000001105144	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0890976	0.0131454	0.0000000000126634	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0770062	0.0113858	0.00000000001399494	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.231253	0.0346926	0.00000000002709852	None	39706196_Hannah-M.-Smith_glucose_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0755713	0.0113779	0.0000000000320485	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0544257	0.00824433	0.00000000004207598	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0754839	0.0114416	0.00000000004330548	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_3
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-12.27	1.86	0.000000000044	-	28002404_body_mass_index_european_ancestry_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0540535	0.0082445	0.00000000005700061	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.00088683	0.00013462	0.0000000000704	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Demerath EW	-	25935004	2015-08-01	Waist circumference	EFO_0004342	Meta-analysis	Table 3	DNA methylation	Waist circumference	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	cm	Illumina HumanMethylation450	Leukocytes and CD4+ T cells	Regression coefficient per 1 SD of waist circumference	3088	2	53.9	Both	European,African	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-	-	0.0000000000815	-	25935004_waist_circumference_metaanalysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0731018	0.0112905	0.00000000009807157	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Hedman AK	-	28213390	2017-02-17	Serum total cholesterol	EFO_0004574	Discovery and replication	Table S2	DNA methylation	Serum total cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	4331	5	65	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.000135	2.08e-05	0.0000000001	-	28213390_serum_total_cholesterol_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0530342	0.00824495	0.0000000001295636	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-13.7	2	0.00000000014	-	28002404_body_mass_index_all_ancestry_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0731207	0.0114773	0.0000000001934948	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-93.55	12.97	0.00000000024	-	28002404_body_mass_index_south_asian_ancestry_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0712058	0.0113653	0.0000000003827134	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_3
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-7.3	1.2	0.00000000042	-	28002404_body_mass_index_all_ancestry_replication
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0373	0.00558	0.00000000051	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Battram T	GEO	27886173	2020-09-15	Inflammatory bowel disease	EFO_0003767	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Inflammatory bowel disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	240	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0357	0.00549	0.00000000051	None	27886173_Battram-T_inflammatory_bowel_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0511581	0.00824576	0.0000000005646397	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_1
Braun KVE	-	28194238	2016-06-16	High-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S1	DNA methylation	High-density lipoprotein cholesterol	Age, sex, smoking, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.017	0.0027	0.000000000578	-	28194238_highdensity_lipoprotein_cholesterol_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0701772	0.0113771	0.0000000007084179	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0701836	0.0113784	0.0000000007090332	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0507684	0.00824592	0.000000000761693	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Liu J	Rotterdam Study III-1, Rotterdam Study II-3 and Rotterdam Study III-2, Netherlands Twin Register, UK adult Twin registry	31197173	2013-06-19	fasting insulin	EFO_0004466	Base	Supplementary Data 1	DNA methylation	fasting insulin	Age, sex, smoking, cell composition (reference based), batch effects	Beta Values	log pmol/L	Illumina HumanMethylation450	whole blood	None	4808	4	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-1.3	0.21	0.00000000085	4740	31197173_Liu-J_fasting_insulin_base
Braun KVE	-	28194238	2016-06-16	High-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for lipid-lowering medication use	Table 3	DNA methylation	High-density lipoprotein cholesterol	Age, sex, smoking, lipid-lowering medication use, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0164	0.0027	0.0000000024	-	28194238_highdensity_lipoprotein_cholesterol_discovery_and_replication_lipidlowering_medication_use_adjusted
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0677155	0.0113811	0.00000000274521	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_2
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	HDL-D	EFO_0008592	Meta-analysis	Table S2	DNA methylation	HDL-D	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	nm	Illumina HumanMethylation450	Whole blood	Mean diameter for HDL particles	5414	4	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.079	0.013	0.0000000028	None	33413638_Gomez-Alonso-MDC_hdl-d_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0671844	0.011389	0.000000003735838	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0244	0.00414	0.0000000048	-	28095459_body_mass_index_framingham_heart_study_batch_2
Ma J	FHS, RS, CARDIA, MESA	30936141	2020-05-22	Hepatic Fat	EFO_0006506, EFO_0008421	Meta-analysis model 1	Table 1	DNA methylation	Hepatic Fat	Age, sex	Beta Values	Hounsfield units	Illumina HumanMethylation450	Whole blood	Model 1 = adjusted for sex + age	3400	4	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	None	None	0.0000000053	None	30936141_Ma-J_hepatic_fat_meta-analysis_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0766265	0.0131776	0.000000006192929	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0477815	0.00824714	0.000000007026023	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_1
Kazmi N	PACE	31230546	2019-06-24	Hypertensive disorders of pregnancy	MONDO_0024664, EFO_0000537, EFO_0000668	Meta analysis adjusted model	Table S2	DNA methylation	Hypertensive disorders of pregnancy	Cell composition (reference based), batch effects, age, smoking, parity, diabetes, body mass index, sex	Beta Values	None	Illumina HumanMethylation450	Cord blood	None	5242	10	Infants	Both	Unclear	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0137	0.0024	0.0000000073	None	31230546_Kazmi-N_hypertensive_disorders_of_pregnancy_meta_analysis_adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0654931	0.0113764	0.000000008738581	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-1.5	0.259	0.00000001	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0656857	0.011459	0.00000001010583	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0660175	0.0115208	0.00000001022453	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0755145	0.0132534	0.00000001237553	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_4
Ma J	FHS, RS, CARDIA, MESA	30936141	2020-05-22	Hepatic Fat	EFO_0006506, EFO_0008421	Meta-analysis model 2	Table 1	DNA methylation	Hepatic Fat	Age, sex	Beta Values	Hounsfield units	Illumina HumanMethylation450	Whole blood	Model 2 = model 1 + smoking + physical activity + alcohol consumption	3400	4	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	None	None	0.000000015	None	30936141_Ma-J_hepatic_fat_meta-analysis_model_2
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication	Table S1	DNA methylation	Triglycerides	Age, sex, smoking, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0131	0.0023	0.0000000152	-	28194238_triglycerides_discovery_and_replication
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery	Table 2	DNA methylation	Triglycerides	Age, sex, smoking, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	725	1	60	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0162	0.0029	0.0000000156	-	28194238_triglycerides_discovery
Battram T	ARIES	None	2020-08-20	Total cholesterol in large HDL	EFO_0004574	None	None	DNA methylation	Total cholesterol in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.64	0.113	0.000000017	None	Battram-T_total_cholesterol_in_large_hdl
Dhana K	Rotterdam study	29762635	2018-05-14	Waist Circumference	EFO_0004342	Discovery	Table 3	DNA methylation	Waist Circumference	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0005	0.000089	0.000000017	None	29762635_Dhana-K_waist_circumference_discovery
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for lipid-lowering medication use	Table 3	DNA methylation	Triglycerides	Age, sex, smoking, lipid-lowering medication use, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.013	0.0023	0.000000019	-	28194238_triglycerides_discovery_and_replication_lipidlowering_medication_use_adjusted
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0638903	0.0113651	0.00000001926131	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Free cholesterol in large HDL	EFO_0008591	None	None	DNA methylation	Free cholesterol in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	2.7	0.48	0.000000023	None	Battram-T_free_cholesterol_in_large_hdl
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.034	0.0061	0.000000025	None	Robert-F-Hillary_Incident_COPD_Basic_model
Battram T	ARIES	None	2020-08-20	Cholesterol esters in large HDL	EFO_0008589	None	None	DNA methylation	Cholesterol esters in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	684	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.84	0.148	0.000000025	None	Battram-T_cholesterol_esters_in_large_hdl
Battram T	ARIES	None	2020-08-20	Total lipids in large HDL	EFO_0004529	None	None	DNA methylation	Total lipids in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.35	0.062	0.00000003	None	Battram-T_total_lipids_in_large_hdl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0456482	0.00824796	0.00000003174931	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0628135	0.0113512	0.00000003190104	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Concentration of large HDL particles	EFO_0004612	None	None	DNA methylation	Concentration of large HDL particles	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	None	None	0.000000036	None	Battram-T_concentration_of_large_hdl_particles
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0623621	0.0113398	0.00000003874574	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Mean diameter for HDL particles	EFO_0008592	None	None	DNA methylation	Mean diameter for HDL particles	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	nm	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.51	0.092	0.000000045	None	Battram-T_mean_diameter_for_hdl_particles
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-	-	0.0000000452	-	26857698_primary_sjogrens_syndrome_whole_blood
Hedman AK	-	28213390	2017-02-17	Serum total cholesterol	EFO_0004574	Discovery	Table S2	DNA methylation	Serum total cholesterol	Age, sex, white cell counts, and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Meta-analysis of 2 discovery cohorts	2306	2	68	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0001493	2.73e-05	0.0000000473	-	28213390_serum_total_cholesterol_discovery
Jiantao Ma	FHS	30796027	Feb 22, 2019	hepatic fat	EFO_0010821	Discovery	Table 1	DNA methylation	hepatic fat	Age, Sex, Cell composition (reference based), Batch effects	Beta values	None	Illumina HumanMethylation450	whole blood	None	1496	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	None	None	0.000000048	None	30796027_Jiantao-Ma_hepatic_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0449087	0.00824824	0.00000005274598	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0617273	0.0113677	0.00000005722726	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Braun KVE	-	28194238	2016-06-16	High-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table 2	DNA methylation	High-density lipoprotein cholesterol	Age, sex, smoking, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	725	1	60	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0196	0.0036	0.0000000644	-	28194238_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for BMI	Table S9	DNA methylation	Serum triglycerides	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	4261	5	65	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.008	0.0015	0.0000000664	-	28213390_serum_triglycerides_discovery_and_replication_adjusted_for_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0445667	0.00824837	0.00000006652492	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0706512	0.013119	0.00000007338967	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0702656	0.0130663	0.00000007663786	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0691091	0.0128752	0.00000008099503	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Battram T	ARIES	None	2020-08-20	Concentration of very large HDL particles	EFO_0004612	None	None	DNA methylation	Concentration of very large HDL particles	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	None	None	0.000000083	None	Battram-T_concentration_of_very_large_hdl_particles
Dhana K	Atherosclerosis Risk in Communities	29762635	2018-05-14	Waist Circumference	EFO_0004342	Replication	Table 3	DNA methylation	Waist Circumference	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	2097	1	Adults	Both	Admixed	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.008	0.00149	0.000000083	None	29762635_Dhana-K_waist_circumference_replication
Demerath EW	-	25935004	2015-08-01	Waist circumference	EFO_0004342	Discovery	Table S5	DNA methylation	Waist circumference	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	cm	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of waist circumference	2097	1	56.2	Both	African	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.008	0.0015	0.0000000834	-	25935004_waist_circumference_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0441231	0.00824853	0.00000008966511	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0440944	0.00824854	0.00000009140335	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.043988	0.00824858	0.00000009814788	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0614019	0.0115176	0.00000009904375	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0604533	0.0113748	0.0000001084224	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Phospholipids in large HDL	EFO_0004639	None	None	DNA methylation	Phospholipids in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.78	0.15	0.00000011	None	Battram-T_phospholipids_in_large_hdl
Battram T	ARIES	None	2020-08-20	HDL cholesterol	EFO_0004612	fasting	None	DNA methylation	HDL cholesterol	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	691	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.31	0.058	0.00000011	None	Battram-T_hdl_cholesterol_fasting
Kazmi N	PACE	31230546	2019-06-24	Hypertensive disorders of pregnancy	MONDO_0024664, EFO_0000537, EFO_0000668	Meta analysis unadjusted model	Table S3	DNA methylation	Hypertensive disorders of pregnancy	None	Beta Values	None	Illumina HumanMethylation450	Cord blood	None	5242	10	Infants	Both	Unclear	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0201	0.0038	0.00000012	None	31230546_Kazmi-N_hypertensive_disorders_of_pregnancy_meta_analysis_unadjusted_model
Nabais MF	AUS, KCL, NL, SGPD, PEG, AIBL	33771206	2021-03-26	Neurodegenerative disorders	EFO_0000253, EFO_0000249, EFO_0002508	Meta-analysis of ALS, AD, PD	Table S3	DNA methylation	Neurodegenerative disorders	Age, Sex, Smoking, batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	Meta-analysis of DNAm sites common to the neurodegenerate disorders Alzheimer<U+2019>s disease, amyotrophic lateral sclerosis, and Parkinson<U+2019>s disease	7322	6	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.48	0.09	0.00000014	None	33771206_Nabais-MF_neurodegenerative_disorders_meta-analysis_of_als__ad__pd
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0595642	0.0113544	0.0000001576658	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Phospholipids in very large HDL	EFO_0004639	None	None	DNA methylation	Phospholipids in very large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	683	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.96	0.18	0.00000017	None	Battram-T_phospholipids_in_very_large_hdl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0684197	0.0131972	0.000000219583	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0669712	0.012948	0.0000002342412	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_4
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-5.77	1.12	0.00000024	-	28002404_body_mass_index_european_ancestry_replication
Battram T	ARIES	None	2020-08-20	Total lipids in very large HDL	EFO_0004529	None	None	DNA methylation	Total lipids in very large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.49	0.093	0.00000024	None	Battram-T_total_lipids_in_very_large_hdl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0425036	0.00824911	0.0000002603691	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	HMGCS1 protein levels (SeqId = 13496-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HMGCS1 protein levels (SeqId = 13496-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hydroxymethylglutaryl-CoA synthase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.86	0.167	0.00000027	None	Gadd-DA_hmgcs1_protein_levels__seqid___13496-19__somascan_protein_measurement
Battram T	ARIES	None	2020-08-20	Waist circumference	EFO_0004342	None	None	DNA methylation	Waist circumference	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	cm	Illumina HumanMethylation450	Whole blood	None	717	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.009	0.0018	0.00000033	None	Battram-T_waist_circumference
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0666146	0.0130778	0.0000003554447	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_4
Kazmi N	PACE	31230546	2019-06-24	Preeclampsia	EFO_0000668	Meta analysis unadjusted model	Table S5	DNA methylation	Preeclampsia	Cell composition (reference based), batch effects, age, smoking, parity, diabetes, body mass index, sex	Beta Values	None	Illumina HumanMethylation450	Cord blood	None	3460	6	Infants	Both	Unclear	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0438	0.0086	0.00000041	None	31230546_Kazmi-N_preeclampsia_meta_analysis_unadjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0417091	0.00824939	0.0000004332567	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0579822	0.011487	0.0000004526779	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Free cholesterol in very large HDL	EFO_0008591	None	None	DNA methylation	Free cholesterol in very large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	684	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	3.7	0.72	0.00000048	None	Battram-T_free_cholesterol_in_very_large_hdl
Gadd DA	Generation Scotland	35945220	31/07/2022	KRT20 protein levels (SeqId = 12975-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KRT20 protein levels (SeqId = 12975-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Keratin, type I cytoskeletal 20	774	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.84	0.167	0.00000049	None	Gadd-DA_krt20_protein_levels__seqid___12975-11__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0559042	0.0112555	0.0000006881277	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.1322106	0.0266669	0.0000007127	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.040865	0.00824967	0.0000007368878	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Battram T	ARIES	None	2020-08-20	Total cholesterol in HDL	EFO_0004574	None	None	DNA methylation	Total cholesterol in HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.33	0.067	0.00000077	None	Battram-T_total_cholesterol_in_hdl
Battram T	ARIES	None	2020-08-20	Phospholipids to total lipids ratio in large HDL	EFO_0004639	None	None	DNA methylation	Phospholipids to total lipids ratio in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	682	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.034	0.0068	0.00000077	None	Battram-T_phospholipids_to_total_lipids_ratio_in_large_hdl
Battram T	GEO	27886173	2020-09-15	Ulcerative colitis	EFO_0000729	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Ulcerative colitis	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	163	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0338	0.00655	0.00000082	None	27886173_Battram-T_ulcerative_colitis_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Ma J	CHARGE	32525743	2020-08-01	Healthy eating	EFO_0002755	Trans-ethnic meta-analysis	Table S13	DNA methylation	Healthy eating	Age, sex, energy intake, cell composition (reference based), batch effects	Beta values	Alternative Healthy Eating Index	Illumina HumanMethylation450	Whole blood, CD4+ T-cells, CD14+ monocytes	See supplement of paper for details on diet scores	9724	7	Adults	Both	European, African, Admixed	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.002	0.001	0.00000099	None	32525743_Ma-J_healthy_eating_trans-ethnic_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0561364	0.0114952	0.000001053358	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Stroke (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Stroke (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14391	1	Adults (18-65y)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.06	0.01227	0.0000011	None	Robert-F-Hillary_Prevalent_Stroke_(Self-report)_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0402058	0.0082499	0.000001107901	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0552431	0.0114088	0.000001297489	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Total cholesterol in HDL2	EFO_0004574	None	None	DNA methylation	Total cholesterol in HDL2	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	684	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.35	0.073	0.0000018	None	Battram-T_total_cholesterol_in_hdl2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0542229	0.0113765	0.000001895055	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0541819	0.0113799	0.000001943101	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Total cholesterol in very large HDL	EFO_0004574	None	None	DNA methylation	Total cholesterol in very large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	683	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.94	0.2	0.0000023	None	Battram-T_total_cholesterol_in_very_large_hdl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P13671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P13671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0388889	0.00825033	0.000002455951	P13671	41361833_Josephine_Robertson_P13671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.053548	0.0114674	0.00000304473	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0607435	0.0131668	0.000003995201	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.037914	0.00825064	0.000004357596	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0523144	0.0113907	0.000004411277	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0377682	0.00825068	0.00000474243	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Battram T	ARIES	None	2020-08-20	Triglycerides in large HDL	EFO_0004530	None	None	DNA methylation	Triglycerides in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	684	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	7	1.5	0.0000051	None	Battram-T_triglycerides_in_large_hdl
Battram T	ARIES	None	2020-08-20	Cholesterol esters to total lipids ratio in large HDL	EFO_0008589	None	None	DNA methylation	Cholesterol esters to total lipids ratio in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	677	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.04	0.0088	0.0000051	None	Battram-T_cholesterol_esters_to_total_lipids_ratio_in_large_hdl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0602959	0.013223	0.000005158254	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P69905	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P69905	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0375697	0.00825074	0.000005318702	P69905	41361833_Josephine_Robertson_P69905_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0514879	0.0113695	0.000005984312	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PLA2G7 protein levels (SeqId = 5015-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLA2G7 protein levels (SeqId = 5015-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet-activating factor acetylhydrolase	774	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.75	0.167	0.0000064	None	Gadd-DA_pla2g7_protein_levels__seqid___5015-15__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.037215	0.00825085	0.000006519551	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Battram T	ARIES	None	2020-08-20	Ratio of apolipoprotein B to apolipoprotein A I	EFO_0004615, EFO_0004614	None	None	DNA methylation	Ratio of apolipoprotein B to apolipoprotein A I	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	685	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.74	0.16	0.0000068	None	Battram-T_ratio_of_apolipoprotein_b_to_apolipoprotein_a_i
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0589537	0.013097	0.000006805748	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0511288	0.0113661	0.00000690106	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Total cholesterol to total lipids ratio in large HDL	EFO_0004574	None	None	DNA methylation	Total cholesterol to total lipids ratio in large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	678	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.028	0.0062	0.000007	None	Battram-T_total_cholesterol_to_total_lipids_ratio_in_large_hdl
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.02	0.0044	0.0000072	None	Battram-T_body_mass_index
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0515997	0.0114968	0.000007238537	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Isoleucine	EFO_0009793	None	None	DNA methylation	Isoleucine	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	679	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-9.1	2	0.0000073	None	Battram-T_isoleucine
Battram T	ARIES	None	2020-08-20	Cholesterol esters in very large HDL	EFO_0008589	None	None	DNA methylation	Cholesterol esters in very large HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	682	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	1.21	0.27	0.0000081	None	Battram-T_cholesterol_esters_in_very_large_hdl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0586776	0.0131791	0.000008557672	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Chronic Pain	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Chronic Pain	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	11591	1	Adults (18-65y)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.077	0.0174	0.0000096	None	Robert-F-Hillary_Incident_Chronic_Pain_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	PAF protein levels (SeqId = 19158-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAF protein levels (SeqId = 19158-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PCNA-associated factor	774	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.73	0.167	0.00001	None	Gadd-DA_paf_protein_levels__seqid___19158-1__somascan_protein_measurement
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 1	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	442	1	67	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0433	0.0095	0.0000105	-	28095459_body_mass_index_framingham_heart_study_batch_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0500455	0.0113865	0.0000111476	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_2
Braun KVE	-	28194238	2016-06-16	High-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for waist circumference	Table 3	DNA methylation	High-density lipoprotein cholesterol	Age, sex, smoking, waist circumference, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0128	0.0029	0.000013	-	28194238_highdensity_lipoprotein_cholesterol_discovery_and_replication_waist_circumference_adjusted
Battram T	ARIES	None	2020-08-20	Android fat free mass	None	None	None	DNA methylation	Android fat free mass	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	701	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.00022	0.000049	0.000013	None	Battram-T_android_fat_free_mass
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0495957	0.0113885	0.00001340374	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13971	1	Adults (18-65y)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.034	0.00782	0.000014	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Fully-adjusted_model
Ochoa-Rosales C	Rotterdam Study	32033992	2020-04-01	Statin use	GO_0036273	Replication	Table 1	Statin use	DNA methylation	sex, age, smoking, body mass index, systolic blood pressure, antihypertensive medication, coronary heart disease, type 2 diabetes, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1450	1	Adults	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0143	0.0033	0.000015	None	32033992_Ochoa-Rosales-C_statin_use_replication
Battram T	ARIES	None	2020-08-20	Android lean mass	EFO_0004995	None	None	DNA methylation	Android lean mass	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	701	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.00022	0.00005	0.000015	None	Battram-T_android_lean_mass
Battram T	ARIES	None	2020-08-20	Trunk total mass	EFO_0004338	None	None	DNA methylation	Trunk total mass	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	699	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.000012	0.0000028	0.000016	None	Battram-T_trunk_total_mass
Battram T	ARIES	None	2020-08-20	Trunk tissue mass	None	None	None	DNA methylation	Trunk tissue mass	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	699	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.000012	0.0000028	0.000017	None	Battram-T_trunk_tissue_mass
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0487559	0.0113808	0.00001847026	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Total fat free mass	None	None	None	DNA methylation	Total fat free mass	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	704	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.000018	0.0000041	0.000019	None	Battram-T_total_fat_free_mass
Battram T	ARIES	None	2020-08-20	Glycoprotein acetyls	EFO_0004555	None	None	DNA methylation	Glycoprotein acetyls	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	683	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.6	0.14	0.000019	None	Battram-T_glycoprotein_acetyls
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0489645	0.0114643	0.00001957717	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0351812	0.00825146	0.00002023861	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0546419	0.0129135	0.00002336837	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07357	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P07357	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0561595	0.0132787	0.00002358622	P07357	41361833_Josephine_Robertson_P07357_OSCA_model_4
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for waist circumference	Table 3	DNA methylation	Triglycerides	Age, sex, smoking, waist circumference, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0104	0.0025	0.000025	-	28194238_triglycerides_discovery_and_replication_waist_circumference_adjusted
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for other lipids	Table 3	DNA methylation	Triglycerides	Age, sex, smoking, other lipids, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.012	0.0028	0.000025	-	28194238_triglycerides_discovery_and_replication_other_lipids_adjusted
Battram T	ARIES	None	2020-08-20	Total lean mass	EFO_0004995	None	None	DNA methylation	Total lean mass	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	704	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.000018	0.0000043	0.000025	None	Battram-T_total_lean_mass
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-23.3	5.5	0.000025	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0485079	0.011518	0.00002552136	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_3
Battram T	ARIES	None	2020-08-20	C-Reactive Protein	EFO_0004458	None	None	DNA methylation	C-Reactive Protein	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mg/l	Illumina HumanMethylation450	Whole blood	None	649	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.071	0.017	0.000027	None	Battram-T_c-reactive_protein
Battram T	ARIES	None	2020-08-20	Insulin	None	fasting	None	DNA methylation	Insulin	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	pmol/l	Illumina HumanMethylation450	Whole blood	None	674	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0053	0.0013	0.000027	None	Battram-T_insulin_fasting
Battram T	ARIES	None	2020-08-20	Concentration of small VLDL particles	EFO_0008317	None	None	DNA methylation	Concentration of small VLDL particles	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mol/l	Illumina HumanMethylation450	Whole blood	None	681	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-9600000	None	0.000029	None	Battram-T_concentration_of_small_vldl_particles
Battram T	ARIES	None	2020-08-20	Triglycerides in small VLDL	EFO_0004530	None	None	DNA methylation	Triglycerides in small VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	680	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-1.01	0.24	0.00003	None	Battram-T_triglycerides_in_small_vldl
Battram T	ARIES	None	2020-08-20	Total lipids in small VLDL	EFO_0004529	None	None	DNA methylation	Total lipids in small VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	681	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.45	0.108	0.000031	None	Battram-T_total_lipids_in_small_vldl
Montano C	-	27074206	2016-05-01	Schizophrenia	EFO_0000692	Discovery	Table S3	DNA methylation	Schizophrenia	Age, sex, smoking, ethnicity, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1334	3	38.6	Both	European,African	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.01	0.0024	0.0000314	-	27074206_schizophrenia_discovery
Battram T	ARIES	None	2020-08-20	Total body mass	EFO_0004338	None	None	DNA methylation	Total body mass	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	704	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0000066	0.0000016	0.000032	None	Battram-T_total_body_mass
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0475168	0.011454	0.0000336562	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Total tissue mass	None	None	None	DNA methylation	Total tissue mass	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	704	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0000066	0.0000016	0.000034	None	Battram-T_total_tissue_mass
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0341228	0.00825176	0.00003565922	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CTHRC1 protein levels (SeqId = 15467-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CTHRC1 protein levels (SeqId = 15467-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collagen triple helix repeat-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.68	0.166	0.000039	None	Gadd-DA_cthrc1_protein_levels__seqid___15467-10__somascan_protein_measurement
Battram T	ARIES	None	2020-08-20	Trunk bone mineral density	EFO_0007591	None	None	DNA methylation	Trunk bone mineral density	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g/cm2	Illumina HumanMethylation450	Whole blood	DXA scan measurement	706	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-1.02	0.25	0.000046	None	Battram-T_trunk_bone_mineral_density
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P69905	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P69905	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0462943	0.0113913	0.00004848878	P69905	41361833_Josephine_Robertson_P69905_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0335089	0.00825193	0.00004917382	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0536869	0.0132238	0.00004935633	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_4
Battram T	ARIES	None	2020-08-20	Free cholesterol to total lipids ratio in large LDL	EFO_0008591	None	None	DNA methylation	Free cholesterol to total lipids ratio in large LDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	680	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.086	0.021	0.000058	None	Battram-T_free_cholesterol_to_total_lipids_ratio_in_large_ldl
Battram T	ARIES	None	2020-08-20	Ribs bone mineral density	EFO_0007591	None	None	DNA methylation	Ribs bone mineral density	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g/cm2	Illumina HumanMethylation450	Whole blood	DXA scan measurement	702	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-1.25	0.31	0.000063	None	Battram-T_ribs_bone_mineral_density
Battram T	ARIES	None	2020-08-20	Android total mass	EFO_0004338	None	None	DNA methylation	Android total mass	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	704	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.000059	0.000015	0.000068	None	Battram-T_android_total_mass
Battram T	ARIES	None	2020-08-20	Android tissue mass	None	None	None	DNA methylation	Android tissue mass	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	704	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.000059	0.000015	0.00007	None	Battram-T_android_tissue_mass
Battram T	ARIES	None	2020-08-20	Hip shaft bone mineral content	EFO_0007621	None	None	DNA methylation	Hip shaft bone mineral content	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	701	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.036	0.009	0.00007	None	Battram-T_hip_shaft_bone_mineral_content
Battram T	ARIES	None	2020-08-20	Hip total bone mineral content	EFO_0007621	None	None	DNA methylation	Hip total bone mineral content	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	702	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.016	0.0041	0.000073	None	Battram-T_hip_total_bone_mineral_content
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0522911	0.0132097	0.00007576756	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	S100A13 protein levels (SeqId = 7223-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	S100A13 protein levels (SeqId = 7223-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein S100-A13	774	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.66	0.167	0.000078	None	Gadd-DA_s100a13_protein_levels__seqid___7223-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MXRA8 protein levels (SeqId = 10521-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MXRA8 protein levels (SeqId = 10521-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Matrix remodeling-associated protein 8	774	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.66	0.167	0.000078	None	Gadd-DA_mxra8_protein_levels__seqid___10521-10__somascan_protein_measurement
Battram T	ARIES	None	2020-08-20	Free cholesterol to total lipids ratio in small HDL	EFO_0008591	None	None	DNA methylation	Free cholesterol to total lipids ratio in small HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	683	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.15	0.038	0.000078	None	Battram-T_free_cholesterol_to_total_lipids_ratio_in_small_hdl
Gadd DA	Generation Scotland	35945220	31/07/2022	PCSK9 protein levels (SeqId = 5231-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PCSK9 protein levels (SeqId = 5231-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proprotein convertase subtilisin/kexin type 9	774	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.66	0.167	0.000079	None	Gadd-DA_pcsk9_protein_levels__seqid___5231-79__somascan_protein_measurement
Battram T	ARIES	None	2020-08-20	Phospholipids in small VLDL	EFO_0004639	None	None	DNA methylation	Phospholipids in small VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	683	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-2	0.5	0.00008	None	Battram-T_phospholipids_in_small_vldl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0520201	0.0132015	0.0000816967	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_4
Battram T	ARIES	None	2020-08-20	Weight	EFO_0004338	None	None	DNA methylation	Weight	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	kg	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.006	0.00153	0.000085	None	Battram-T_weight
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0450297	0.0114761	0.00008756724	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	PCOLCE protein levels (SeqId = 11237-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PCOLCE protein levels (SeqId = 11237-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Procollagen C-endopeptidase enhancer 1	774	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.65	0.167	0.000089	None	Gadd-DA_pcolce_protein_levels__seqid___11237-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0323088	0.00825226	0.00009076034	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P13671	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P13671	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.044444	0.0113878	0.00009551657	P13671	41361833_Josephine_Robertson_P13671_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Triglycerides in VLDL	EFO_0004530	None	None	DNA methylation	Triglycerides in VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	677	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.23	0.058	0.000096	None	Battram-T_triglycerides_in_vldl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0448584	0.0115257	0.00009984399	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_3