author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	-0.0034	0.00022	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	0.012	0.0013	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	0.24575	0.01103	2.8999999999999996e-55	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	-	-	6.109999999999999e-40	-	28056824_age_4_vs_age_0
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	-	-	2.98e-31	-	23526956_clear_cell_renal_carcinoma
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	0.0031	None	1.0000000000000001e-28	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Huan T	None	31282290	2019-07-17	miR-370	SO_0000276	None	Table S3	DNA methylation	miR-370	Batch effects, cell composition (reference free), age, sex, ancestry (other)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	3565	1	Adults	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	4.8	0.54	2.9e-19	None	31282290_Huan-T_mir-370
Huan T	None	31282290	2019-07-17	miR-127-3p	SO_0000276	None	Table S3	DNA methylation	miR-127-3p	Batch effects, cell composition (reference free), age, sex, ancestry (other)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	3565	1	Adults	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	3.8	0.45	4.4e-17	None	31282290_Huan-T_mir-127-3p
Huan T	None	31282290	2019-07-17	miR-668	SO_0000276	None	Table S3	DNA methylation	miR-668	Batch effects, cell composition (reference free), age, sex, ancestry (other)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	3565	1	Adults	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	4.5	0.57	0.0000000000000023	None	31282290_Huan-T_mir-668
Huan T	None	31282290	2019-07-17	miR-543	SO_0000276	None	Table S3	DNA methylation	miR-543	Batch effects, cell composition (reference free), age, sex, ancestry (other)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	3565	1	Adults	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	3.3	0.48	0.00000000001	None	31282290_Huan-T_mir-543
Huan T	None	31282290	2019-07-17	miR-654-5p	SO_0000276	None	Table S3	DNA methylation	miR-654-5p	Batch effects, cell composition (reference free), age, sex, ancestry (other)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	3565	1	Adults	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	3.6	0.56	0.000000000056	None	31282290_Huan-T_mir-654-5p
Huan T	None	31282290	2019-07-17	miR-411-3p	SO_0000276	None	Table S3	DNA methylation	miR-411-3p	Batch effects, cell composition (reference free), age, sex, ancestry (other)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	3565	1	Adults	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	2.9	0.44	0.000000000058	None	31282290_Huan-T_mir-411-3p
Huan T	None	31282290	2019-07-17	miR-409-3p	SO_0000276	None	Table S3	DNA methylation	miR-409-3p	Batch effects, cell composition (reference free), age, sex, ancestry (other)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	3565	1	Adults	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	2.7	0.42	0.000000000071	None	31282290_Huan-T_mir-409-3p
Huan T	None	31282290	2019-07-17	miR-382-5p	SO_0000276	None	Table S3	DNA methylation	miR-382-5p	Batch effects, cell composition (reference free), age, sex, ancestry (other)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	3565	1	Adults	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	3.5	0.58	0.0000000026	None	31282290_Huan-T_mir-382-5p
Huan T	None	31282290	2019-07-17	miR-376a-3p	SO_0000276	None	Table S3	DNA methylation	miR-376a-3p	Batch effects, cell composition (reference free), age, sex, ancestry (other)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	3565	1	Adults	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	3.5	0.6	0.000000004	None	31282290_Huan-T_mir-376a-3p
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	-0.0436694	0.0082487	0.0000001213282	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	-0.0418402	0.00825896	0.0000004111123	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	-0.0412517	0.00825784	0.0000005937134	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	-0.02	0.004	0.00000075	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	-0.0387267	0.00829144	0.000003028724	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Joubert BR	PACE	27040690	2016-04-07	Maternal smoking in pregnancy	EFO_0006527, EFO_0005671, EFO_0004318, EFO_0002950	Sustained maternal smoking in pregnancy effect on newborns	Table S3	DNA methylation	Maternal smoking in pregnancy	Maternal age, maternal education, parity and technical covariates	Beta values	-	Illumina HumanMethylation450	Cord blood	-	5647	9	0	Missing	European,African,Admixed,Other	cg18089426	chr14:101175970	14	101175970	-	Island	0.013	0.003	0.0000117	-	27040690_maternal_smoking_in_pregnancy_sustained_maternal_smoking_in_pregnancy_effect_on_newborns
Sikdar S	PACE	31536415	2019-09-19	Prenatal smoke exposure	EFO_0009115, EFO_0008361, EFO_0006527, EFO_0004318	Inverse varience-weighted fixed-effects meta-analysis	Table S1	DNA methylation	Prenatal smoke exposure	Maternal age, socioeconomic position, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Cord blood, whole blood	None	5648	9	Infants	Both	European, African, Unclear	cg18089426	chr14:101175970	14	101175970	-	Island	0.0127	0.003	0.000028	None	31536415_Sikdar-S_prenatal_smoke_exposure_inverse_varience-weighted_fixed-effects_meta-analysis
Joubert BR	PACE	27040690	2016-04-07	Maternal smoking in pregnancy	EFO_0006527, EFO_0005671, EFO_0004318, EFO_0002950	Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts	Table S3	DNA methylation	Maternal smoking in pregnancy	Maternal age, maternal education, parity, white blood cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Cord blood	-	5647	9	0	Missing	European,African,Admixed,Other	cg18089426	chr14:101175970	14	101175970	-	Island	0.013	0.003	0.0000281	-	27040690_maternal_smoking_in_pregnancy_sustained_maternal_smoking_in_pregnancy_effect_on_newborns_adjusted_for_cell_counts
Joubert BR	PACE	27040690	2016-04-07	Maternal smoking in pregnancy	EFO_0006527, EFO_0005671, EFO_0004318, EFO_0002950	Any maternal smoking in pregnancy effect on newborns	Table S3	DNA methylation	Maternal smoking in pregnancy	Maternal age, maternal education, parity and technical covariates	Beta values	-	Illumina HumanMethylation450	Cord blood	-	6685	13	0	Missing	European,East Asian,African,Admixed,Other	cg18089426	chr14:101175970	14	101175970	-	Island	0.01	0.003	0.0000325	-	27040690_maternal_smoking_in_pregnancy_any_maternal_smoking_in_pregnancy_effect_on_newborns
Priyanka Choudhary	PACE	38052982	Dec 5, 2023	Maternal education at the time of pregnancy	None	Model3_Adolescence	None	DNA methylation	Maternal education at the time of pregnancy	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Body mass index, Gestational age, offspring BMI, offspring smoking	Beta values	years of schooling	Illumina HumanMethylation450	Whole blood	Illumina HumanMethylationEPIC was also used for some cohorts	2740	None	Children	Both	European	cg18089426	chr14:101175970	14	101175970	-	Island	-0.0026	0.00066	0.000064	None	38052982_Priyanka-Choudhary_maternal_education_at_the_time_of_pregnancy_model3_adolescence