author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.012	0.00046	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.033	0.0021	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.012	None	6.6e-308	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.174011	0.00829452	2.64709e-96	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.169585	0.00818088	4.177685e-94	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.169574	0.00818114	4.35384e-94	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.161006	0.00814885	8.871163e-86	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.28693	0.01288	3.0999999999999996e-55	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-	-	5.76e-45	-	28056824_age_4_vs_age_0
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.611	0.046	5.7e-40	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.51	0.046	1.1000000000000002e-28	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ALPI protein levels (SeqId = 17441-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALPI protein levels (SeqId = 17441-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intestinal-type alkaline phosphatase	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.46	0.046	1.8e-23	None	Gadd-DA_alpi_protein_levels__seqid___17441-4__somascan_protein_measurement
Raffield LM	The Jackson Heart Study	31985870	2020-01-27	Coagulation factor VIII	EFO_0004634, EFO_0004630	None	Table 5	Coagulation factor VIII	DNA methylation	Cell composition (reference based), batch effects, age, ssex, ancestry (genomic PCs)	None	Beta Values	Illumina HumanMethylationEPIC	Whole blood	None	1670	1	Adults	Both	African	cg21160290	chr9:136149941	9	136149941	ABO	North shore	None	None	5.2e-22	None	31985870_Raffield-LM_coagulation_factor_viii
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 8983-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 8983-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.42	0.046	9.8e-20	None	Gadd-DA_golm1_protein_levels__seqid___8983-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 17456-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 17456-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.4	0.046	9.3e-18	None	Gadd-DA_golm1_protein_levels__seqid___17456-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	F8 protein levels (SeqId = 13499-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	F8 protein levels (SeqId = 13499-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coagulation factor VIII	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.35	0.046	0.000000000000018	None	Gadd-DA_f8_protein_levels__seqid___13499-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 10613-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 10613-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.31	0.046	0.000000000029	None	Gadd-DA_casc4_protein_levels__seqid___10613-33__somascan_protein_measurement
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.044	0.0061	0.00000000014	None	32795589_Kyung-WK_eosinophilia_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	LRRC32 protein levels (SeqId = 7551-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LRRC32 protein levels (SeqId = 7551-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transforming growth factor beta activator LRRC32	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.29	0.046	0.00000000044	None	Gadd-DA_lrrc32_protein_levels__seqid___7551-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXND1 protein levels (SeqId = 19561-216)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXND1 protein levels (SeqId = 19561-216)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-D1	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.24	0.046	0.00000029	None	Gadd-DA_plxnd1_protein_levels__seqid___19561-216__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DPEP2 protein levels (SeqId = 8327-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPEP2 protein levels (SeqId = 8327-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dipeptidase 2	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.23	0.046	0.00000062	None	Gadd-DA_dpep2_protein_levels__seqid___8327-26__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.016	0.0031	0.00000067	None	33450751_Mulder-RH_sex_discovery
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.00035979	7.51e-05	0.00000188	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	ICAM5 protein levels (SeqId = 5124-69)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ICAM5 protein levels (SeqId = 5124-69)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intercellular adhesion molecule 5	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.2	0.046	0.00001	None	Gadd-DA_icam5_protein_levels__seqid___5124-69__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.0362213	0.00825115	0.00001142214	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Hoang	Agricultural Lung Health Study	34516295	Sep 13, 2021	chlordane	None	discovery	10.5281/zenodo.5156585	DNA methylation	chlordane	Age, Smoking, Cell composition (reference based), residence,asthma	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	1132	1	Adults	Males	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.04174	0.01	0.000029	None	34516295_Hoang_chlordane_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	EPHA4 protein levels (SeqId = 16288-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPHA4 protein levels (SeqId = 16288-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ephrin type-A receptor 4	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.18	0.046	0.000082	None	Gadd-DA_epha4_protein_levels__seqid___16288-17__somascan_protein_measurement