author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg21072581	chr5:156749711	5	156749711	CYFIP2	Open sea	-1.72	0.315	0.000000051	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.000002	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg07933297	chr19:45879792	19	45879792	-	Open sea	-0.99	0.21	0.0000022	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25578949	chr5:964230	5	964230	-	Open sea	0.84	0.179	0.0000029	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg03631596	chr13:73301985	13	73301985	C13orf37;C13orf34	Island	-0.55	0.118	0.000003	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg19761269	chr8:107282284	8	107282284	OXR1	Island	0.52	0.113	0.0000044	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg08772345	chr8:56367723	8	56367723	XKR4;SBF1P1	Open sea	-0.65	0.142	0.000005	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg04447424	chr18:33709794	18	33709794	SLC39A6;ELP2	Island	-0.33	0.073	0.0000052	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00795915	chr5:70751728	5	70751728	BDP1	Island	-0.7	0.153	0.0000056	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg15836028	chr8:103129234	8	103129234	NCALD	Open sea	0.79	0.174	0.0000058	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg20441193	chr15:33990454	15	33990454	RYR3	Open sea	1.1	0.244	0.000006	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg15278043	chr7:130353539	7	130353539	TSGA13;COPG2	Island	-0.65	0.145	0.0000063	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg24341498	chr9:137217390	9	137217390	RXRA	Island	-0.49	0.108	0.0000068	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg20163056	chr19:5005982	19	5005982	KDM4B	Open sea	-0.9	0.2	0.000007	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg26688775	chr6:167704942	6	167704942	UNC93A	Open sea	0.47	0.106	0.000007	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg22704520	chr2:200820451	2	200820451	C2orf60;C2orf47	Island	-0.4	0.09	0.000008	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg11544714	chr7:86781625	7	86781625	DMTF1	Island	-0.31	0.069	0.000008	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg12831925	chr11:10326785	11	10326785	ADM	South shore	0.89	0.199	0.0000083	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg04953516	chr8:125968220	8	125968220	-	Open sea	0.85	0.191	0.0000083	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg19646139	chr1:2029012	1	2029012	PRKCZ	South shelf	-0.62	0.14	0.0000085	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg20320455	chr1:82014804	1	82014804	LOC101927434	Open sea	0.85	0.192	0.0000087	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg20377095	chr2:25937815	2	25937815	-	Open sea	0.8	0.18	0.0000091	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg20346096	chr18:77794830	18	77794830	C18orf22	South shore	0.76	0.171	0.0000093	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg01028389	chr16:87079265	16	87079265	-	Open sea	-0.59	0.134	0.0000095	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg10796068	chr19:10957709	19	10957709	C19orf38	Open sea	0.74	0.167	0.00001	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg10122474	chr14:88459471	14	88459471	GALC	Island	-0.61	0.139	0.000011	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00603498	chr17:5322775	17	5322775	RPAIN;NUP88	Island	-0.54	0.123	0.000011	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg04342230	chr11:8986449	11	8986449	TMEM9B;TMEM9B-AS1	Island	-0.58	0.133	0.000011	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg15251319	chr3:194836302	3	194836302	C3orf21	Open sea	-0.83	0.188	0.000012	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg10927968	chr11:1807333	11	1807333	-	Open sea	0.6	0.136	0.000012	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg16082166	chr14:89259075	14	89259075	EML5	Island	0.76	0.174	0.000013	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25910466	chr20:21283998	20	21283998	XRN2	Island	-0.37	0.084	0.000014	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg15516877	chr16:75670113	16	75670113	KARS	Open sea	-0.96	0.222	0.000015	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg19402268	chr1:67802560	1	67802560	IL12RB2	Open sea	-0.65	0.15	0.000016	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg13320318	chr8:19819682	8	19819682	LPL	Open sea	0.83	0.193	0.000018	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg26260369	chr14:68141723	14	68141723	VTI1B	Island	-0.39	0.091	0.000019	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg20710777	chr5:110411740	5	110411740	TSLP	South shelf	-0.6	0.141	0.00002	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg11319586	chr10:62255296	10	62255296	ANK3	Open sea	0.63	0.148	0.00002	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00867472	chr1:156714808	1	156714808	HDGF	South shelf	-1.07	0.251	0.000021	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg06733736	chr16:3661771	16	3661771	BTBD12	Island	-0.69	0.162	0.000021	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg09000178	chr16:67063319	16	67063319	CBFB	Island	-0.41	0.096	0.000021	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg18678643	chr6:157149477	6	157149477	ARID1B	Open sea	-0.79	0.186	0.000021	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg13390975	chr5:34915890	5	34915890	BRIX1;RAD1	Island	-0.32	0.076	0.000022	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg21631525	chr18:73424715	18	73424715	-	Open sea	-1.23	0.291	0.000025	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg18334734	chr5:87959611	5	87959611	LOC645323	South shelf	-0.59	0.141	0.000026	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg11538810	chr22:46481727	22	46481727	LOC400931	North shore	-1	0.239	0.000026	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg18265326	chr16:65635738	16	65635738	-	Open sea	-0.52	0.124	0.000026	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg14017991	chr1:26560780	1	26560780	CCDC21	Island	-0.61	0.146	0.000029	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg10878976	chr5:1257084	5	1257084	TERT	Island	-0.73	0.175	0.000029	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg24654547	chr16:68057165	16	68057165	DUS2L;DDX28	Island	-0.36	0.086	0.000029	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg04785299	chr10:134019556	10	134019556	-	Island	-0.47	0.113	0.00003	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg20634125	chr6:16407331	6	16407331	ATXN1	Open sea	0.74	0.178	0.000032	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg04323605	chr3:16090394	3	16090394	-	Open sea	0.6	0.144	0.000032	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00631327	chr8:3965218	8	3965218	CSMD1	Open sea	0.53	0.127	0.000033	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg12957797	chr14:88156815	14	88156815	-	Open sea	0.35	0.084	0.000033	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg04265971	chr4:2470698	4	2470698	RNF4	Island	-0.64	0.155	0.000035	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg06364629	chr2:27592939	2	27592939	EIF2B4;SNX17	Island	-0.46	0.112	0.000036	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg07458698	chr2:67624494	2	67624494	ETAA1	Island	-0.78	0.188	0.000037	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg05575921	chr5:373378	5	373378	AHRR	North shore	-0.47	0.113	0.000037	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg08537845	chr5:167715532	5	167715532	-	North shelf	0.49	0.118	0.000038	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg09241703	chr14:89831698	14	89831698	FOXN3	Open sea	0.48	0.116	0.000039	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg05914852	chr12:122622979	12	122622979	MLXIP	Open sea	-0.65	0.159	0.000039	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg10676442	chr3:12525808	3	12525808	TSEN2	Island	-0.7	0.172	0.00004	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg06077741	chr3:43121458	3	43121458	C3orf39	Island	-0.72	0.175	0.000044	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg24950749	chr20:1310425	20	1310425	SDCBP2	South shelf	-0.74	0.181	0.000044	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg13992493	chr6:169092333	6	169092333	-	Open sea	-0.63	0.154	0.000046	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg23551527	chr5:92927574	5	92927574	NR2F1;MIR548AO	North shore	0.54	0.134	0.000046	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00475034	chr16:68501448	16	68501448	-	Open sea	1.18	0.29	0.000047	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg07189338	chr6:41040461	6	41040461	NFYA;OARD1	Island	-0.52	0.129	0.000051	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg23033923	chr7:111202442	7	111202442	IMMP2L	Island	-0.68	0.169	0.000054	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg23342576	chr19:39686118	19	39686118	NCCRP1	North shore	0.76	0.188	0.000054	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg10169976	chr2:65454837	2	65454837	ACTR2	Island	-0.57	0.141	0.000057	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg21891597	chr8:132936123	8	132936123	EFR3A	Open sea	0.66	0.165	0.000057	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg05691848	chr22:46610981	22	46610981	PPARA	South shore	-0.76	0.189	0.000059	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg22167208	chr2:219744145	2	219744145	WNT10A	North shore	0.61	0.152	0.000059	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg17183174	chr13:76115526	13	76115526	-	South shelf	0.6	0.149	0.00006	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg18985987	chr12:70637240	12	70637240	CNOT2;LINC01481	Island	-0.46	0.114	0.00006	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg03004916	chr18:77384741	18	77384741	-	North shelf	0.84	0.209	0.00006	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg21411702	chr6:32028841	6	32028841	TNXB	Open sea	1.01	0.251	0.000061	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg03671660	chr21:40554907	21	40554907	PSMG1	Island	-0.58	0.145	0.000064	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg05258550	chr7:105241786	7	105241786	-	Open sea	0.63	0.157	0.000064	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg26649251	chr19:44598564	19	44598564	ZNF224	Island	-0.37	0.093	0.000065	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg09225336	chr16:65635750	16	65635750	-	Open sea	-0.47	0.118	0.000065	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg05770748	chr11:69511722	11	69511722	-	Open sea	1.05	0.262	0.000065	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg04192862	chr10:28966472	10	28966472	BAMBI	Island	-0.6	0.151	0.000068	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg04298340	chr19:38397738	19	38397738	WDR87;SIPA1L3	Island	-0.93	0.233	0.000068	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg27317218	chr14:75894692	14	75894692	JDP2	Island	-0.5	0.126	0.00007	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg23910413	chr5:140105405	5	140105405	VTRNA1-3	Open sea	0.27	0.067	0.000071	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg07229198	chr6:30685635	6	30685635	MDC1	South shore	-0.66	0.166	0.000071	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg19420069	chr16:65635834	16	65635834	-	Open sea	-0.44	0.11	0.000071	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg02744670	chr4:2470688	4	2470688	RNF4	Island	-0.48	0.12	0.000072	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg09082427	chr9:140349184	9	140349184	NSMF	South shore	-0.55	0.14	0.000074	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg11321092	chr5:144325284	5	144325284	-	Open sea	0.39	0.098	0.000075	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg20433952	chr17:55607898	17	55607898	MSI2	Open sea	-0.82	0.208	0.000075	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg24789434	chr4:3526865	4	3526865	LRPAP1	Island	-0.92	0.233	0.000076	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg08076102	chr22:24125924	22	24125924	MMP11	North shelf	-0.95	0.24	0.000077	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg10241347	chr10:124639260	10	124639260	LOC399815;FAM24B	Island	-0.27	0.07	0.000081	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg11452354	chr6:44187052	6	44187052	SLC29A1	North shore	0.56	0.142	0.000083	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg08655589	chr3:14444175	3	14444175	SLC6A6	Island	-0.45	0.115	0.000085	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg02283181	chr1:2165868	1	2165868	SKI	Open sea	-0.82	0.209	0.000086	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg10994086	chr3:166834125	3	166834125	-	Open sea	-0.51	0.131	0.000087	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg05561058	chr19:18533591	19	18533591	SSBP4	South shelf	0.91	0.233	0.000087	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg07797882	chr5:149698722	5	149698722	-	Open sea	0.87	0.222	0.000088	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg02027735	chr20:37233764	20	37233764	C20orf95	South shelf	0.43	0.109	0.000088	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg01292398	chr1:158110665	1	158110665	LOC646268	Open sea	-0.84	0.215	0.000089	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25037165	chr11:12824283	11	12824283	TEAD1	Open sea	0.27	0.069	0.00009	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg06642177	chr6:134496341	6	134496341	SGK1	Island	-0.28	0.071	0.000091	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg02171859	chr7:853441	7	853441	-	North shore	0.51	0.13	0.000091	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg05751059	chr17:79848657	17	79848657	ALYREF;ANAPC11	Island	-0.67	0.173	0.000096	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg08173535	chr9:127533861	9	127533861	NR6A1	South shore	-0.63	0.162	0.000097	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement