author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15628834	chr15:74285377	15	74285377	STOML1	South shore	-0.15	0.0193	0.0000000000000061	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17308151	chr11:8703888	11	8703888	RPL27A	Island	0.1	0.0134	0.0000000000001	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18565264	chr1:2140551	1	2140551	C1orf86	North shelf	-0.1	0.0155	0.000000000025	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27379240	chr5:112042919	5	112042919	APC	North shore	-0.08	0.0123	0.000000000094	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06563790	chr10:88459587	10	88459587	LDB3	Open sea	-0.08	0.0126	0.00000000024	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16788099	chr11:67141792	11	67141792	LOC100130987;CLCF1	South shore	0.087	0.0139	0.00000000057	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24590431	chr22:22398683	22	22398683	-	Open sea	-0.12	0.0197	0.00000000086	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27415945	chr20:1310451	20	1310451	FKBP1A-SDCBP2;SDCBP2-AS1;SDCBP2	South shelf	-0.11	0.019	0.000000002	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23900548	chr8:141312701	8	141312701	TRAPPC9	Open sea	-0.095	0.0158	0.0000000021	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16156013	chr21:36419332	21	36419332	RUNX1	Open sea	0.091	0.0153	0.0000000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15302213	chr15:70921188	15	70921188	-	Open sea	-0.1	0.0175	0.0000000037	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05234760	chr8:6692470	8	6692470	XKR5	Island	0.072	0.0124	0.000000008	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07106881	chr4:1004554	4	1004554	FGFRL1	Island	0.066	0.0115	0.000000011	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09899914	chr9:140172190	9	140172190	TOR4A	North shore	0.067	0.0116	0.000000012	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18430372	chr19:11076300	19	11076300	SMARCA4	South shelf	-0.16	0.0273	0.000000012	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09317403	chr14:92994936	14	92994936	RIN3	Open sea	-0.1	0.0183	0.000000013	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23018755	chr17:79881529	17	79881529	MAFG	South shore	-0.097	0.017	0.000000014	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08638320	chr1:47900265	1	47900265	FOXD2;MGC12982	Island	-0.081	0.0144	0.000000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21144006	chr12:74931510	12	74931510	LOC552889	Island	0.081	0.0144	0.000000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26205771	chr8:53851156	8	53851156	NPBWR1	North shore	0.062	0.0112	0.000000026	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23326517	chr9:73169165	9	73169165	TRPM3	Open sea	-0.092	0.0166	0.000000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18766882	chr1:231664214	1	231664214	TSNAX-DISC1;TSNAX	Island	-0.094	0.017	0.000000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04757806	chr11:94278595	11	94278595	FUT4	Island	-0.16	0.0285	0.000000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13298504	chr17:47275098	17	47275098	-	Open sea	-0.059	0.0108	0.00000004	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23501228	chr6:75917468	6	75917468	-	South shore	0.07	0.0128	0.000000055	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05075025	chr6:43842160	6	43842160	-	Open sea	-0.1	0.0184	0.00000006	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06930252	chr22:50903229	22	50903229	SBF1	Island	-0.1	0.0185	0.000000075	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12153148	chr16:8946147	16	8946147	-	Open sea	-0.11	0.0203	0.000000075	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18845289	chr12:121124611	12	121124611	MLEC	Island	0.077	0.0143	0.000000079	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03087880	chr16:49666012	16	49666012	ZNF423	North shelf	-0.089	0.0168	0.0000001	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	ch.1.230766435F	chr1:232699812	1	232699812	-	Open sea	0.088	0.0166	0.00000015	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04451485	chr6:170048365	6	170048365	WDR27	Open sea	-0.077	0.0148	0.00000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04905421	chr16:1581129	16	1581129	IFT140	North shelf	-0.095	0.0185	0.00000026	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26076724	chr6:15090163	6	15090163	-	Open sea	-0.091	0.0177	0.0000003	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07294295	chr12:3103790	12	3103790	TEAD4	Open sea	-0.046	0.0089	0.0000003	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22682848	chr19:18785514	19	18785514	-	Open sea	-0.075	0.0146	0.00000031	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10563063	chr16:70734236	16	70734236	VAC14	Open sea	-0.1	0.0203	0.00000031	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18771195	chr17:182656	17	182656	RPH3AL	North shelf	-0.062	0.0121	0.00000032	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02548252	chr18:70419005	18	70419005	NETO1	Open sea	-0.066	0.0129	0.00000032	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03882071	chr17:43922210	17	43922210	LOC100128977;IMP5	Open sea	-0.14	0.0273	0.00000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15658793	chr19:3398810	19	3398810	NFIC	Island	-0.11	0.0223	0.00000038	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25207738	chr17:72306215	17	72306215	DNAI2	Open sea	-0.091	0.0179	0.00000041	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05625341	chr14:50612578	14	50612578	SOS2	Open sea	-0.049	0.0098	0.00000044	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21143956	chr8:125769926	8	125769926	-	Open sea	0.072	0.0142	0.00000045	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17608931	chr17:1898897	17	1898897	RTN4RL1	North shelf	0.11	0.0217	0.0000005	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18331224	chr6:138290249	6	138290249	-	Open sea	0.073	0.0146	0.0000005	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21232203	chr20:57574714	20	57574714	CTSZ	Open sea	-0.072	0.0144	0.00000054	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00004700	chr2:106013885	2	106013885	FHL2	North shore	-0.062	0.0124	0.00000058	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05830758	chr2:3606519	2	3606519	RNASEH1-AS1;RNASEH1	South shore	0.072	0.0145	0.00000062	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12460254	chr1:21629726	1	21629726	ECE1	Open sea	-0.13	0.0258	0.00000075	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14825688	chr5:132208181	5	132208181	LEAP2	Open sea	-0.086	0.0174	0.0000008	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00207494	chr7:148703518	7	148703518	PDIA4	Open sea	-0.12	0.0238	0.00000081	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27377213	chr20:37433803	20	37433803	PPP1R16B	North shore	0.059	0.0119	0.00000085	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02168436	chr14:37644675	14	37644675	-	South shelf	0.045	0.0092	0.00000088	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20455854	chr5:139040849	5	139040849	CXXC5	Island	-0.083	0.0168	0.00000093	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14554351	chr10:4213136	10	4213136	-	Open sea	-0.099	0.0202	0.00000095	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13231546	chr6:38557009	6	38557009	BTBD9	Open sea	-0.087	0.0177	0.000001	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22193912	chr17:79881523	17	79881523	MAFG	South shore	-0.085	0.0173	0.0000011	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13103259	chr18:54813330	18	54813330	-	Open sea	-0.082	0.0167	0.0000011	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06431105	chr19:18572378	19	18572378	ELL	North shore	-0.066	0.0136	0.0000011	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06505229	chr2:106719539	2	106719539	UXS1	Open sea	-0.1	0.0208	0.0000011	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10853746	chr14:50864245	14	50864245	CDKL1	South shore	-0.11	0.0229	0.0000012	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18555277	chr6:170581248	6	170581248	-	South shore	0.027	0.0057	0.0000013	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19427948	chr16:4937024	16	4937024	PPL	South shore	-0.12	0.0239	0.0000014	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16028098	chr16:85391641	16	85391641	-	North shelf	-0.081	0.0168	0.0000015	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26867987	chr6:33131450	6	33131450	COL11A2	South shore	-0.066	0.0137	0.0000017	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07067232	chr9:123299310	9	123299310	CDK5RAP2	Open sea	0.054	0.0113	0.0000017	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09563600	chr10:71170571	10	71170571	TACR2	South shore	-0.04	0.0083	0.0000017	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24866638	chr1:80520037	1	80520037	-	Open sea	-0.11	0.0238	0.0000017	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24367390	chr18:58752217	18	58752217	-	Open sea	-0.035	0.0074	0.0000017	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18514949	chr5:133563216	5	133563216	PPP2CA	South shore	-0.08	0.0167	0.0000018	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19872463	chr12:6881629	12	6881629	LAG3	North shore	0.052	0.011	0.0000018	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26758486	chr17:71533286	17	71533286	SDK2	Open sea	-0.069	0.0145	0.0000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15997497	chr11:95948847	11	95948847	MAML2	Open sea	0.062	0.0129	0.0000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27346741	chr3:142312112	3	142312112	-	North shelf	0.067	0.014	0.0000021	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02506659	chr3:31328041	3	31328041	-	Open sea	0.054	0.0113	0.0000022	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09629105	chr2:129231058	2	129231058	-	South shore	0.06	0.0126	0.0000023	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08020573	chr1:231666092	1	231666092	TSNAX;TSNAX-DISC1	South shore	0.071	0.015	0.0000023	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19530457	chr19:12777885	19	12777885	MAN2B1;WDR83	North shore	-0.06	0.0127	0.0000024	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07918994	chr7:2208759	7	2208759	MAD1L1	Open sea	-0.085	0.0181	0.0000025	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12331108	chr16:19132987	16	19132987	-	Open sea	-0.12	0.0254	0.0000027	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18937014	chr1:117484934	1	117484934	PTGFRN	North shelf	-0.11	0.0241	0.0000028	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02048968	chr5:188824	5	188824	PLEKHG4B	North shelf	0.062	0.0132	0.0000028	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08260861	chr7:147830671	7	147830671	CNTNAP2;MIR548T	Open sea	0.13	0.0276	0.0000028	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13211021	chr6:111819981	6	111819981	TRAF3IP2-AS1	Open sea	-0.1	0.0219	0.0000028	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22462702	chr17:43487833	17	43487833	ARHGAP27	Open sea	0.063	0.0135	0.0000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25326241	chr1:6243152	1	6243152	-	South shore	-0.068	0.0144	0.0000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11192688	chr1:171226702	1	171226702	FMO1	Open sea	-0.088	0.0187	0.000003	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11127021	chr15:96472677	15	96472677	-	Open sea	0.064	0.0137	0.000003	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22241686	chr13:42242375	13	42242375	VWA8	Open sea	-0.071	0.0152	0.0000031	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21872375	chr4:83295347	4	83295347	HNRNPD	Island	-0.07	0.0149	0.0000032	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17324980	chr19:10396843	19	10396843	ICAM1;ICAM4	North shore	-0.09	0.0193	0.0000033	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12971325	chr12:109027932	12	109027932	SELPLG	Open sea	0.069	0.0148	0.0000033	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02934718	chr17:59521299	17	59521299	-	Open sea	-0.074	0.0159	0.0000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19847743	chr7:111436976	7	111436976	DOCK4	Open sea	0.063	0.0135	0.0000036	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21335583	chr21:45968442	21	45968442	TSPEAR	Open sea	-0.064	0.0139	0.0000038	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17039461	chr7:641283	7	641283	LOC101926963;PRKAR1B	North shelf	0.071	0.0154	0.0000038	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03583463	chr6:167372938	6	167372938	-	South shelf	0.062	0.0134	0.0000038	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27514181	chr12:31100025	12	31100025	TSPAN11	Open sea	-0.078	0.0168	0.0000043	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26605006	chr16:30197364	16	30197364	CORO1A	South shelf	0.066	0.0143	0.0000043	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15157151	chr12:9917374	12	9917374	-	Open sea	0.058	0.0127	0.0000043	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25539555	chr1:8285172	1	8285172	-	Open sea	-0.095	0.0207	0.0000044	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19035378	chr6:52907284	6	52907284	ICK	Open sea	-0.03	0.0066	0.0000047	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26009702	chr2:20178592	2	20178592	WDR35	Open sea	-0.057	0.0124	0.000005	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02813126	chr10:115241025	10	115241025	-	Open sea	-0.068	0.015	0.000005	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09032544	chr1:167487295	1	167487295	CD247	Open sea	0.081	0.0176	0.0000051	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22413388	chr22:46367617	22	46367617	WNT7B	Island	0.037	0.0082	0.0000052	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01793237	chr3:72795741	3	72795741	-	Open sea	-0.08	0.0176	0.0000052	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06127256	chr16:73206588	16	73206588	-	Open sea	-0.052	0.0113	0.0000054	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15631787	chr22:19044965	22	19044965	DGCR2	Open sea	-0.11	0.0251	0.0000054	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16388983	chr1:214720805	1	214720805	PTPN14	North shelf	-0.097	0.0214	0.0000057	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19954537	chr2:97204401	2	97204401	ARID5A	South shore	0.053	0.0117	0.0000057	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05512505	chr19:7968863	19	7968863	MAP2K7	Island	0.063	0.014	0.0000059	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24771908	chr10:131584276	10	131584276	-	Open sea	-0.065	0.0144	0.000006	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25605120	chr5:66511837	5	66511837	-	Open sea	0.067	0.0147	0.0000061	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07972026	chr6:1636961	6	1636961	GMDS	Open sea	-0.082	0.0181	0.0000062	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15221994	chr17:8782480	17	8782480	PIK3R5	Open sea	-0.051	0.0113	0.0000062	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22487450	chr22:36894326	22	36894326	FOXRED2	South shore	-0.07	0.0156	0.0000064	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02152290	chr7:551601	7	551601	PDGFA	South shore	-0.054	0.012	0.0000066	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03978658	chr8:37761565	8	37761565	-	Open sea	-0.099	0.022	0.0000066	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00184690	chr7:67890188	7	67890188	-	Open sea	0.077	0.017	0.0000066	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01100203	chr12:25348358	12	25348358	CASC1;LYRM5	Island	0.059	0.013	0.0000068	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11411148	chr16:12623631	16	12623631	SNX29	Open sea	-0.09	0.0199	0.0000068	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20947849	chr1:7514232	1	7514232	CAMTA1	Open sea	0.079	0.0176	0.0000069	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22926923	chr14:102054053	14	102054053	-	Island	-0.062	0.0139	0.0000073	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23931437	chr22:33023190	22	33023190	SYN3	Open sea	0.061	0.0136	0.0000073	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23225454	chr1:865583	1	865583	SAMD11	North shelf	-0.077	0.0171	0.0000074	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19741026	chr7:962743	7	962743	ADAP1	North shelf	0.055	0.0124	0.0000076	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09414807	chr11:68214432	11	68214432	LRP5	North shore	-0.081	0.0181	0.0000077	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26030741	chr21:37442155	21	37442155	CBR1;LOC100133286	Island	0.03	0.0067	0.000008	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23228694	chr20:35089521	20	35089521	DLGAP4	Island	-0.047	0.0106	0.0000085	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14626029	chr6:130704336	6	130704336	TMEM200A	Open sea	-0.096	0.0215	0.0000085	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10014443	chr20:35903602	20	35903602	-	Open sea	0.07	0.0157	0.0000086	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01159543	chr21:37442141	21	37442141	CBR1;LOC100133286	Island	0.036	0.008	0.0000086	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05271068	chr22:17745385	22	17745385	CECR3	Open sea	-0.094	0.0211	0.0000089	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12603369	chr2:205147389	2	205147389	-	Open sea	-0.063	0.0143	0.000009	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21661379	chr2:228324983	2	228324983	-	Open sea	0.075	0.0168	0.000009	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05134325	chr13:52423122	13	52423122	-	Open sea	-0.097	0.0218	0.000009	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07213830	chr1:1093940	1	1093940	-	South shore	-0.094	0.0212	0.0000092	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07524902	chr20:52329496	20	52329496	-	Open sea	-0.096	0.0216	0.0000092	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19497734	chr4:144257218	4	144257218	GAB1	Island	0.07	0.0158	0.0000093	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12183741	chr6:88031886	6	88031886	C6orf162;GJB7	North shore	-0.1	0.0233	0.0000094	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05214130	chr12:123945990	12	123945990	SNRNP35	South shelf	-0.09	0.0204	0.0000095	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21848407	chr17:61499094	17	61499094	TANC2	Open sea	0.067	0.0151	0.0000097	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12221474	chr20:37433936	20	37433936	PPP1R16B	North shore	0.061	0.0138	0.0000097	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24898863	chr1:153363580	1	153363580	S100A8	Open sea	-0.089	0.02	0.00001	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11793663	chr4:20884476	4	20884476	KCNIP4	Open sea	-0.036	0.0081	0.00001	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12041209	chr22:24603877	22	24603877	-	Open sea	-0.069	0.0156	0.00001	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02669225	chr1:113742602	1	113742602	-	South shore	-0.095	0.0215	0.000011	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11119596	chr3:111261010	3	111261010	CD96	Open sea	0.075	0.017	0.000011	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12253437	chr6:32813448	6	32813448	TAP1;PSMB8	South shore	0.053	0.0121	0.000011	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24660086	chr10:86005121	10	86005121	RGR	Open sea	-0.061	0.0138	0.000011	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16906885	chr14:91696151	14	91696151	-	North shelf	0.058	0.0133	0.000011	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23459483	chr3:195997651	3	195997651	PCYT1A	Open sea	0.094	0.0215	0.000012	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24757097	chr19:56806277	19	56806277	-	Open sea	-0.1	0.0229	0.000012	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25546991	chr2:96811841	2	96811841	DUSP2	South shore	0.067	0.0152	0.000012	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09904177	chr6:26538194	6	26538194	HMGN4	North shore	0.038	0.0088	0.000013	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14951598	chr6:41472931	6	41472931	-	Island	-0.05	0.0116	0.000013	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13912307	chr11:47416535	11	47416535	-	Island	0.049	0.0112	0.000013	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08319194	chr20:62451390	20	62451390	ZBTB46-AS1	Open sea	-0.059	0.0135	0.000013	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08816563	chr12:68198050	12	68198050	-	Open sea	0.074	0.0169	0.000013	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05603004	chr11:47747889	11	47747889	FNBP4	Open sea	-0.091	0.0209	0.000013	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05574033	chr6:170587994	6	170587994	FLJ38122	North shore	0.048	0.011	0.000013	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04227581	chr2:16059290	2	16059290	MYCNUT	Open sea	-0.11	0.0243	0.000013	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02319067	chr16:29757461	16	29757461	C16orf54	Open sea	0.068	0.0157	0.000014	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13964104	chr1:66820623	1	66820623	PDE4B	Open sea	-0.063	0.0146	0.000014	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10939783	chr10:29970747	10	29970747	SVIL	Open sea	0.065	0.0149	0.000014	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18501370	chr2:233095029	2	233095029	DIS3L2	Open sea	-0.044	0.01	0.000014	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04784321	chr14:91828035	14	91828035	CCDC88C	Open sea	-0.092	0.0212	0.000014	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09913171	chr12:133010946	12	133010946	-	South shore	-0.039	0.0089	0.000015	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01144592	chr16:11158227	16	11158227	CLEC16A	Open sea	-0.084	0.0194	0.000015	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19851816	chr22:50657907	22	50657907	TUBGCP6	Island	-0.056	0.013	0.000015	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00960440	chr12:719749	12	719749	NINJ2	South shore	0.064	0.0148	0.000015	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01526854	chr6:41900498	6	41900498	BYSL	Open sea	-0.13	0.0295	0.000016	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01962969	chr21:37442104	21	37442104	CBR1	North shore	0.036	0.0083	0.000016	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06987842	chr5:169350993	5	169350993	DOCK2;FAM196B	Open sea	-0.11	0.0255	0.000016	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08446194	chr1:54124735	1	54124735	GLIS1	Open sea	-0.054	0.0126	0.000016	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04632268	chr12:12618135	12	12618135	LOH12CR1	Open sea	-0.077	0.0179	0.000016	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05602862	chr2:14775046	2	14775046	FAM84A	Island	-0.036	0.0083	0.000017	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26357596	chr5:54397592	5	54397592	GZMA	Open sea	0.06	0.014	0.000017	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26927634	chr16:89004858	16	89004858	CBFA2T3	North shore	-0.069	0.0159	0.000017	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13272296	chr4:153877907	4	153877907	FHDC1	Open sea	-0.081	0.0187	0.000017	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07451531	chr11:67040865	11	67040865	ADRBK1	Open sea	-0.11	0.0247	0.000017	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13517213	chr2:211419746	2	211419746	CPS1	Open sea	0.06	0.0139	0.000017	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07836663	chr1:2066167	1	2066167	PRKCZ	North shore	0.097	0.0226	0.000018	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00409844	chr5:68798649	5	68798649	OCLN	Open sea	-0.082	0.0191	0.000018	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20740903	chr17:76170799	17	76170799	TK1	Open sea	-0.098	0.0229	0.000018	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22359162	chr17:27041306	17	27041306	RAB34	North shelf	0.083	0.0194	0.000018	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10189817	chr1:204952533	1	204952533	NFASC	South shore	0.059	0.0137	0.000018	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27524103	chr3:187957576	3	187957576	LPP	Open sea	0.052	0.0122	0.000018	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06357326	chr9:134554814	9	134554814	RAPGEF1	Open sea	-0.085	0.0199	0.000018	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19977951	chr20:46113223	20	46113223	-	Open sea	-0.08	0.0187	0.000018	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08730743	chr1:2189027	1	2189027	SKI	Open sea	-0.076	0.0178	0.000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01032589	chr5:123885297	5	123885297	-	Open sea	0.055	0.0129	0.000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25574227	chr10:73153701	10	73153701	-	North shelf	-0.092	0.0215	0.000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09063173	chr13:36288415	13	36288415	MIR548F5	Open sea	-0.099	0.023	0.000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03525786	chr5:76085956	5	76085956	-	Open sea	-0.088	0.0206	0.000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03656996	chr15:40601261	15	40601261	PLCB2	Open sea	0.053	0.0124	0.000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05073325	chr11:128065159	11	128065159	-	Open sea	0.059	0.0139	0.000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08600585	chr17:35447040	17	35447040	ACACA	Open sea	0.058	0.0136	0.000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01621637	chr1:168074478	1	168074478	GPR161	Open sea	0.085	0.02	0.000019	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04351205	chr2:143886326	2	143886326	ARHGAP15	Open sea	0.053	0.0124	0.00002	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00498816	chr3:13665022	3	13665022	FBLN2	Open sea	-0.068	0.0159	0.00002	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23007898	chr6:27263965	6	27263965	-	Open sea	-0.059	0.0137	0.00002	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16606773	chr20:19955806	20	19955806	RIN2	Island	-0.081	0.0189	0.00002	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03688497	chr14:77417243	14	77417243	-	Open sea	-0.095	0.0222	0.00002	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00211835	chr1:242149795	1	242149795	-	Open sea	-0.072	0.0169	0.00002	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25913475	chr1:32716807	1	32716807	LCK	South shelf	0.06	0.014	0.000021	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23895418	chr20:34078780	20	34078780	CEP250	Open sea	0.067	0.0158	0.000021	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21312657	chr2:220079434	2	220079434	ABCB6	North shelf	-0.079	0.0185	0.000021	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11010140	chr17:34900632	17	34900632	GGNBP2	Island	0.05	0.0118	0.000022	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15963112	chr5:163343677	5	163343677	-	Open sea	0.066	0.0156	0.000022	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23470684	chr15:90749351	15	90749351	SEMA4B	Open sea	-0.11	0.0249	0.000022	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19302474	chr6:94755518	6	94755518	-	Open sea	-0.048	0.0113	0.000022	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11723904	chr16:3724734	16	3724734	TRAP1	Island	-0.087	0.0205	0.000023	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00674043	chr18:61254447	18	61254447	SERPINB13	Open sea	-0.089	0.0209	0.000023	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16143491	chr15:28355804	15	28355804	-	North shore	-0.081	0.0191	0.000023	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16671138	chr14:50864320	14	50864320	CDKL1	South shore	-0.072	0.0169	0.000023	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11741071	chr18:74767106	18	74767106	MBP	North shelf	0.065	0.0154	0.000023	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02394664	chr10:6572395	10	6572395	PRKCQ	Open sea	0.11	0.0257	0.000023	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12974773	chr2:64330510	2	64330510	PELI1	Open sea	0.072	0.017	0.000024	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01543184	chr17:79881543	17	79881543	MAFG	South shore	-0.077	0.0182	0.000024	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10028941	chr1:184121919	1	184121919	-	Open sea	0.064	0.0152	0.000024	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17379806	chr1:111417489	1	111417489	CD53	Open sea	0.057	0.0135	0.000024	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12044599	chr11:67206308	11	67206308	CORO1B;PTPRCAP	South shelf	0.079	0.0188	0.000025	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23673224	chr21:44029985	21	44029985	LOC101928233	Open sea	0.047	0.0113	0.000025	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08650179	chr5:139990030	5	139990030	-	Open sea	-0.067	0.0158	0.000025	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27613737	chr21:47038433	21	47038433	-	Open sea	-0.065	0.0155	0.000025	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14358411	chr13:61187712	13	61187712	-	Open sea	-0.089	0.0212	0.000025	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08250415	chr2:181854305	2	181854305	UBE2E3	Open sea	-0.048	0.0115	0.000025	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27373387	chr2:10592414	2	10592414	-	South shelf	-0.073	0.0173	0.000026	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14871225	chr5:139040820	5	139040820	CXXC5	Island	-0.084	0.0199	0.000026	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09344348	chr6:170581085	6	170581085	-	Island	0.018	0.0044	0.000026	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03473518	chr13:20805656	13	20805656	GJB6	North shore	0.052	0.0123	0.000026	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15009130	chr3:56996451	3	56996451	ARHGEF3	Open sea	-0.096	0.0227	0.000026	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17415730	chr9:81880073	9	81880073	-	Open sea	0.069	0.0164	0.000026	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13423262	chr6:35108939	6	35108939	TCP11	Island	0.025	0.0059	0.000026	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06461649	chr3:122862913	3	122862913	PDIA5	Open sea	-0.081	0.0193	0.000026	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11747820	chr1:29584023	1	29584023	PTPRU	North shore	0.064	0.0151	0.000027	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22888752	chr2:220253668	2	220253668	DNPEP	South shore	-0.08	0.019	0.000027	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08531489	chr17:42189331	17	42189331	HDAC5	Open sea	-0.15	0.0365	0.000027	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24357463	chr17:59478953	17	59478953	TBX2	Island	0.048	0.0114	0.000027	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20078972	chr19:15391832	19	15391832	BRD4	Open sea	-0.082	0.0195	0.000027	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08903441	chr17:80304981	17	80304981	-	South shore	0.058	0.0139	0.000028	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24080247	chr21:38082613	21	38082613	SIM2	South shore	0.063	0.015	0.000028	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08266285	chr16:2176928	16	2176928	PKD1	North shore	-0.096	0.0228	0.000028	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09167301	chr14:91790497	14	91790497	CCDC88C	Open sea	0.056	0.0134	0.000028	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12032370	chr10:102976942	10	102976942	-	Island	0.053	0.0127	0.000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01447914	chr11:63974955	11	63974955	FERMT3	Island	0.056	0.0133	0.000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22656705	chr13:20207391	13	20207391	MPHOSPH8	North shore	0.047	0.0111	0.000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03583495	chr16:89121585	16	89121585	-	South shore	-0.088	0.0209	0.000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21100638	chr17:4337082	17	4337082	SPNS3	Open sea	0.059	0.014	0.000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26906383	chr2:33260139	2	33260139	LTBP1	Open sea	-0.054	0.0129	0.000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26175420	chr11:107650702	11	107650702	-	Open sea	-0.065	0.0155	0.000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19888099	chr22:23274312	22	23274312	-	Open sea	0.1	0.0246	0.000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06947754	chr16:12190216	16	12190216	SNX29	Open sea	-0.075	0.0178	0.000029	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25658278	chr12:52607461	12	52607461	LOC283404	Open sea	0.051	0.0123	0.00003	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27447219	chr13:99174373	13	99174373	STK24	Open sea	-0.077	0.0185	0.00003	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03238075	chr17:21113363	17	21113363	TMEM11	North shelf	-0.056	0.0134	0.00003	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09805644	chr15:69847820	15	69847820	-	Open sea	-0.068	0.0164	0.00003	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15066174	chr5:140501311	5	140501311	PCDHB4	North shore	0.037	0.0089	0.00003	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11152617	chr7:22401787	7	22401787	-	Open sea	-0.092	0.022	0.00003	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11553983	chr4:48340688	4	48340688	-	North shelf	-0.091	0.0218	0.000031	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15889847	chr14:65183532	14	65183532	PLEKHG3	Open sea	-0.11	0.027	0.000031	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03913806	chr17:39654589	17	39654589	-	Open sea	-0.081	0.0195	0.000031	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00425213	chr1:6446095	1	6446095	ACOT7	Open sea	-0.072	0.0172	0.000032	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17675088	chr5:93013224	5	93013224	FAM172A	Open sea	-0.096	0.0231	0.000032	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00228390	chr6:168197667	6	168197667	C6orf123	Island	0.031	0.0074	0.000032	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11414267	chr10:99694717	10	99694717	CRTAC1	Open sea	-0.026	0.0062	0.000032	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07351688	chr14:96727613	14	96727613	BDKRB1	Open sea	-0.051	0.0124	0.000032	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07514040	chr18:2972319	18	2972319	LPIN2	Open sea	0.06	0.0145	0.000032	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15043362	chr5:173765196	5	173765196	LINC01411	Open sea	-0.05	0.0121	0.000032	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17906803	chr1:19587393	1	19587393	-	Open sea	-0.078	0.0188	0.000033	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04161576	chr6:53158523	6	53158523	ELOVL5	Open sea	-0.11	0.0253	0.000033	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07571230	chr17:55896840	17	55896840	-	Open sea	-0.1	0.0253	0.000033	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01831743	chr12:110352941	12	110352941	TCHP	Open sea	-0.11	0.0264	0.000034	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11544522	chr15:70828097	15	70828097	-	Open sea	0.051	0.0123	0.000034	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10377921	chr19:15391946	19	15391946	BRD4	Open sea	-0.14	0.0331	0.000034	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12262507	chr3:147797340	3	147797340	-	Open sea	-0.071	0.0171	0.000034	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14376170	chr1:156647971	1	156647971	NES	South shore	0.05	0.0121	0.000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14381881	chr15:48629566	15	48629566	DUT	Open sea	0.062	0.015	0.000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22169777	chr21:37560793	21	37560793	DOPEY2	Open sea	-0.085	0.0205	0.000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00645687	chr10:115704988	10	115704988	-	Open sea	-0.085	0.0205	0.000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09762932	chr20:31121583	20	31121583	NOL4L	North shelf	-0.12	0.0279	0.000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10786904	chr9:134902660	9	134902660	MED27	Open sea	-0.082	0.0198	0.000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01703004	chr12:51718155	12	51718155	BIN2	Open sea	0.06	0.0146	0.000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13050408	chr1:25353861	1	25353861	-	Open sea	0.087	0.0209	0.000035	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14418802	chr1:9299979	1	9299979	H6PD	Open sea	0.06	0.0145	0.000036	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04956362	chr7:866406	7	866406	UNC84A	South shelf	-0.14	0.0328	0.000036	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20136100	chr11:63974860	11	63974860	FERMT3	Island	0.061	0.0146	0.000036	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14590805	chr11:108405292	11	108405292	EXPH5	Open sea	-0.082	0.0197	0.000036	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23811850	chr6:24936246	6	24936246	FAM65B	Open sea	0.054	0.0132	0.000036	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03731303	chr3:181443009	3	181443009	SOX2OT	North shore	0.06	0.0145	0.000037	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11992241	chr17:7036993	17	7036993	-	Open sea	0.042	0.0102	0.000037	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25352189	chr14:105532022	14	105532022	GPR132	Open sea	0.061	0.0148	0.000037	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16795830	chr6:31554199	6	31554199	LST1	Open sea	0.05	0.0121	0.000038	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13998093	chr17:44896877	17	44896877	WNT3	Island	0.061	0.0148	0.000038	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21132229	chr17:40757728	17	40757728	FAM134C	North shelf	-0.11	0.0259	0.000038	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25355826	chr9:100992217	9	100992217	MIR6854;TBC1D2	Open sea	-0.072	0.0174	0.000038	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13047217	chr8:636871	8	636871	ERICH1	North shore	-0.026	0.0063	0.000038	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06429483	chr9:132536018	9	132536018	-	Open sea	-0.093	0.0224	0.000038	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15060048	chr5:57557530	5	57557530	-	Open sea	-0.079	0.0192	0.000038	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24849439	chr3:39851927	3	39851927	MYRIP	South shore	0.062	0.015	0.000039	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23736754	chr8:119117303	8	119117303	EXT1	Open sea	-0.097	0.0236	0.000039	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19901940	chr14:22689870	14	22689870	-	Open sea	0.043	0.0105	0.000039	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24448171	chr15:31597352	15	31597352	-	Open sea	-0.063	0.0153	0.000039	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03282313	chr2:113545053	2	113545053	-	Open sea	-0.11	0.0258	0.000039	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01236268	chr22:49552838	22	49552838	-	Open sea	-0.063	0.0154	0.00004	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08191899	chr21:35501530	21	35501530	MRPS6	Open sea	-0.047	0.0115	0.00004	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02226192	chr16:89461734	16	89461734	ANKRD11	Open sea	-0.11	0.0267	0.000041	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27455470	chr3:46448702	3	46448702	CCRL2;LOC102724297	Open sea	0.051	0.0124	0.000041	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22733626	chr14:105532014	14	105532014	GPR132	Open sea	0.039	0.0095	0.000041	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03726628	chr1:6088407	1	6088407	KCNAB2	South shore	0.059	0.0145	0.000041	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22885540	chr7:155794551	7	155794551	-	Open sea	0.092	0.0224	0.000042	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03852454	chr17:78848608	17	78848608	RPTOR	North shore	-0.052	0.0126	0.000042	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13345353	chr2:242715022	2	242715022	GAL3ST2	South shelf	-0.055	0.0135	0.000043	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27324455	chr4:166248807	4	166248807	SC4MOL	Island	0.055	0.0135	0.000043	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06916868	chr5:38656019	5	38656019	LIFR-AS1	Open sea	-0.04	0.0097	0.000043	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25136126	chr11:64784445	11	64784445	ARL2-SNX15;ARL2	South shelf	-0.068	0.0166	0.000043	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06765813	chr20:17673308	20	17673308	BANF2	Open sea	-0.044	0.0107	0.000043	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27551227	chr7:154877217	7	154877217	HTR5A	Open sea	0.03	0.0073	0.000044	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18850418	chr2:33359289	2	33359289	LTBP1	Open sea	-0.085	0.0208	0.000044	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26289989	chr6:51085750	6	51085750	-	Open sea	-0.05	0.0123	0.000044	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12310383	chr7:132157787	7	132157787	PLXNA4	Open sea	-0.1	0.0251	0.000044	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26336642	chr2:36467699	2	36467699	-	Open sea	0.055	0.0135	0.000045	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27269112	chr2:219246969	2	219246969	SLC11A1	Open sea	-0.11	0.026	0.000045	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19466818	chr17:56409534	17	56409534	MIR142	Open sea	0.052	0.0128	0.000046	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27391655	chr4:7293316	4	7293316	SORCS2	Open sea	-0.048	0.0119	0.000046	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19206260	chr16:85559016	16	85559016	-	Open sea	-0.1	0.0257	0.000046	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20968200	chr11:67070164	11	67070164	SSH3	North shore	-0.098	0.0241	0.000046	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00432058	chr4:15423127	4	15423127	C1QTNF7;LOC101929095	Open sea	0.049	0.0119	0.000046	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10314909	chr1:2524890	1	2524890	MMEL1	North shelf	-0.041	0.0101	0.000047	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23349326	chr7:47623469	7	47623469	-	South shore	-0.055	0.0136	0.000047	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10487414	chr1:114522498	1	114522498	OLFML3	Open sea	-0.07	0.0172	0.000047	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06374595	chr2:66723348	2	66723348	MEIS1	Open sea	-0.076	0.0188	0.000047	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27503577	chr17:76089079	17	76089079	TNRC6C	Open sea	-0.074	0.0181	0.000047	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15280310	chr5:7924375	5	7924375	-	Open sea	0.046	0.0112	0.000047	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26865481	chr4:41206196	4	41206196	APBB2	Open sea	0.076	0.0187	0.000048	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04093671	chr17:40010128	17	40010128	KLHL11	Open sea	-0.05	0.0122	0.000048	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21381967	chr19:35992835	19	35992835	DMKN	Open sea	-0.081	0.02	0.000048	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06233873	chr5:137641727	5	137641727	CDC25C	Open sea	-0.061	0.015	0.000048	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08972009	chr12:3262208	12	3262208	TSPAN9	Open sea	0.062	0.0153	0.000048	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03650987	chr16:68993689	16	68993689	TANGO6	Open sea	-0.1	0.0247	0.000048	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22329743	chr2:208688774	2	208688774	PLEKHM3	Open sea	-0.086	0.0212	0.000049	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10065182	chr12:49182837	12	49182837	ADCY6	North shore	0.043	0.0106	0.000049	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23924647	chr12:122227872	12	122227872	RHOF	North shelf	0.054	0.0133	0.000049	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05798125	chr16:28996362	16	28996362	LAT	Open sea	0.051	0.0126	0.000049	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09564484	chr9:127206689	9	127206689	-	Open sea	-0.081	0.02	0.000049	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22717323	chr7:2094977	7	2094977	MAD1L1	Open sea	-0.052	0.0129	0.00005	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08291886	chr8:66546652	8	66546652	ARMC1	South shore	-0.052	0.0128	0.00005	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17427323	chr7:29073004	7	29073004	CPVL	Open sea	0.068	0.0168	0.00005	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg00415011	chr8:142046261	8	142046261	-	Open sea	0.057	0.0139	0.000051	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06313941	chr11:9005008	11	9005008	NRIP3	Open sea	-0.065	0.016	0.000051	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05175964	chr15:72103133	15	72103133	NR2E3	North shore	0.11	0.0279	0.000052	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10007418	chr9:97679650	9	97679650	C9orf3	Open sea	-0.092	0.0227	0.000052	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18258597	chr3:39066509	3	39066509	-	Open sea	0.065	0.0161	0.000052	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04408387	chr1:38183556	1	38183556	EPHA10	Open sea	-0.021	0.0051	0.000052	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17778888	chr5:510421	5	510421	SLC9A3	South shore	-0.049	0.0121	0.000053	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03984055	chr16:31117318	16	31117318	-	Island	-0.095	0.0234	0.000053	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08272205	chr10:97190690	10	97190690	SORBS1	Open sea	0.041	0.0102	0.000053	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18052369	chr5:99970791	5	99970791	-	Open sea	-0.038	0.0094	0.000053	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03471777	chr9:37384521	9	37384521	-	Open sea	0.072	0.0177	0.000054	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14374581	chr17:4813227	17	4813227	-	Open sea	-0.094	0.0231	0.000054	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04283628	chr22:37477029	22	37477029	TMPRSS6	Open sea	-0.085	0.0211	0.000054	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02032642	chr14:86034651	14	86034651	FLRT2	Open sea	0.044	0.0108	0.000055	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09153895	chr17:58179869	17	58179869	LOC653653	Open sea	0.027	0.0067	0.000055	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25966133	chr14:23025474	14	23025474	-	Open sea	0.059	0.0146	0.000055	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23776787	chr5:142814315	5	142814315	NR3C1	Open sea	0.068	0.0167	0.000055	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21384961	chr6:6885899	6	6885899	-	Open sea	-0.1	0.0256	0.000055	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19848538	chr12:112586276	12	112586276	TRAFD1	Open sea	-0.088	0.0218	0.000055	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22538454	chr1:39844881	1	39844881	MACF1	Open sea	-0.07	0.0174	0.000055	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24130798	chr22:44068318	22	44068318	EFCAB6	Open sea	-0.069	0.0171	0.000055	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20204701	chr11:46388245	11	46388245	DGKZ	Island	-0.056	0.014	0.000056	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14081667	chr21:44782497	21	44782497	-	Island	0.031	0.0077	0.000056	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04355708	chr2:218252963	2	218252963	DIRC3	Open sea	-0.057	0.0141	0.000056	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18482776	chr11:70952015	11	70952015	-	Open sea	0.053	0.013	0.000056	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18902644	chr6:2460774	6	2460774	-	Open sea	-0.1	0.0259	0.000057	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19776201	chr19:58951434	19	58951434	ZNF132	Island	0.064	0.0158	0.000058	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20650545	chr19:39826677	19	39826677	GMFG	Open sea	0.055	0.0136	0.000058	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12505727	chr22:43150078	22	43150078	-	Open sea	-0.092	0.0229	0.000058	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04785985	chr9:132956048	9	132956048	NCS1	Open sea	-0.065	0.0162	0.000058	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21333208	chr4:3475372	4	3475372	DOK7	South shore	-0.053	0.0131	0.000059	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27129144	chr17:78848533	17	78848533	RPTOR	North shore	-0.062	0.0153	0.000059	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08545864	chr2:74153305	2	74153305	DGUOK	North shore	-0.083	0.0206	0.000059	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18279090	chr2:182607410	2	182607410	-	Open sea	-0.048	0.0119	0.000059	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21004490	chr1:26872337	1	26872337	RPS6KA1	Open sea	0.057	0.0142	0.00006	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18447972	chr17:7036934	17	7036934	-	Open sea	0.041	0.0102	0.00006	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11746531	chr17:25784992	17	25784992	-	South shore	-0.083	0.0206	0.00006	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26321407	chr20:47357214	20	47357214	PREX1	Open sea	-0.11	0.0274	0.00006	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07461953	chr7:151503602	7	151503602	PRKAG2	Open sea	-0.081	0.0202	0.000061	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18313769	chr15:84107647	15	84107647	-	Open sea	-0.046	0.0116	0.000061	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26198107	chr18:77336216	18	77336216	-	Island	-0.05	0.0126	0.000062	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03252196	chr12:113646285	12	113646285	IQCD	Open sea	0.055	0.0137	0.000062	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16408805	chr14:50864343	14	50864343	CDKL1	South shore	-0.081	0.0203	0.000062	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20023079	chr20:34078800	20	34078800	CEP250	Open sea	0.064	0.016	0.000062	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15409399	chr5:72252490	5	72252490	FCHO2	Island	0.047	0.0117	0.000063	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16882206	chr8:115466108	8	115466108	-	Open sea	-0.053	0.0133	0.000063	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17356255	chr20:45947895	20	45947895	LOC100131496;ZMYND8	Open sea	-0.11	0.0269	0.000064	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10183963	chr9:137263731	9	137263731	RXRA	Open sea	-0.093	0.0233	0.000064	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26402421	chr17:56407092	17	56407092	BZRAP1;BZRAP1-AS1	Open sea	0.059	0.0147	0.000065	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26279021	chr7:19158349	7	19158349	TWIST1	South shore	0.051	0.0128	0.000066	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06929216	chr13:99135607	13	99135607	STK24	Open sea	-0.057	0.0142	0.000066	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12026561	chr11:122238873	11	122238873	-	Open sea	-0.092	0.0229	0.000066	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13910465	chr7:81191708	7	81191708	-	Open sea	-0.05	0.0125	0.000066	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20292467	chr16:66400565	16	66400565	CDH5	Open sea	-0.086	0.0215	0.000066	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11803251	chr4:41659108	4	41659108	LIMCH1	Open sea	-0.1	0.0257	0.000067	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19698472	chr5:53966914	5	53966914	-	Open sea	-0.07	0.0176	0.000067	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27121758	chr19:3178742	19	3178742	S1PR4	Island	0.058	0.0146	0.000067	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09538135	chr21:38593663	21	38593663	-	Island	0.063	0.0158	0.000067	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04807217	chr20:57329420	20	57329420	-	North shore	0.088	0.0222	0.000067	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27604917	chr15:81589273	15	81589273	IL16	Open sea	0.06	0.0151	0.000067	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg10975897	chr6:15504844	6	15504844	JARID2	Open sea	-0.076	0.0192	0.000068	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07629017	chr8:53851613	8	53851613	NPBWR1	North shore	0.057	0.0143	0.000068	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19621317	chr12:50467278	12	50467278	ASIC1	Open sea	-0.076	0.0191	0.000068	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25898162	chr4:75023005	4	75023005	MTHFD2L	North shore	-0.065	0.0163	0.000068	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20841906	chr3:160822911	3	160822911	B3GALNT1	Island	-0.042	0.0105	0.000069	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01795160	chr9:95727505	9	95727505	FGD3	Open sea	0.058	0.0145	0.000069	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg19804345	chr19:13908843	19	13908843	ZSWIM4	South shelf	-0.089	0.0225	0.000069	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25212571	chr1:153114115	1	153114115	SPRR2C	Open sea	-0.082	0.0205	0.00007	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09688546	chr4:157997363	4	157997363	GLRB	Island	-0.044	0.011	0.00007	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18496653	chr21:38593042	21	38593042	-	Island	0.034	0.0087	0.00007	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06658146	chr4:58029765	4	58029765	-	North shore	-0.066	0.0165	0.000071	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17642426	chr10:124739963	10	124739963	PSTK	Island	0.038	0.0095	0.000071	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03135060	chr13:31776205	13	31776205	B3GLCT	South shore	-0.069	0.0173	0.000071	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17975791	chr4:156561415	4	156561415	-	Open sea	0.038	0.0094	0.000071	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20369287	chr20:56194242	20	56194242	ZBP1	Open sea	0.057	0.0144	0.000072	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04898167	chr20:39928730	20	39928730	ZHX3	Open sea	-0.064	0.0161	0.000072	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24262376	chr1:151137274	1	151137274	SCNM1;LYSMD1	Open sea	-0.058	0.0147	0.000073	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16332159	chr16:28505959	16	28505959	APOB48R	North shelf	0.059	0.0149	0.000073	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07467095	chr1:232781741	1	232781741	-	Open sea	-0.07	0.0176	0.000073	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21377860	chr7:150174540	7	150174540	GIMAP8	Open sea	0.064	0.0161	0.000074	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08536841	chr19:49250452	19	49250452	IZUMO1	North shelf	0.055	0.0138	0.000074	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08025214	chr8:101704984	8	101704984	-	Open sea	-0.046	0.0117	0.000074	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16580762	chr19:8634137	19	8634137	MYO1F	Open sea	0.057	0.0144	0.000074	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11856371	chr11:12130831	11	12130831	MICAL2	North shore	-0.095	0.0239	0.000074	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18182111	chr5:37835111	5	37835111	GDNF	Island	0.058	0.0147	0.000075	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01399981	chr16:87812658	16	87812658	-	North shore	-0.059	0.0148	0.000075	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg11974897	chr1:36636835	1	36636835	MAP7D1	Open sea	-0.11	0.0272	0.000075	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18552437	chr4:38051357	4	38051357	TBC1D1	Open sea	-0.087	0.022	0.000075	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09518009	chr14:27243163	14	27243163	-	Open sea	-0.042	0.0107	0.000076	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17138019	chr15:90704685	15	90704685	-	Open sea	-0.11	0.0276	0.000076	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07697635	chr5:77656183	5	77656183	SCAMP1	Island	-0.051	0.0129	0.000077	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04156606	chr10:134859458	10	134859458	-	North shore	-0.066	0.0167	0.000077	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07255415	chr20:62583740	20	62583740	UCKL1;UCKL1-AS1	North shelf	-0.075	0.0188	0.000077	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg18832428	chr13:95611711	13	95611711	LINC00557	Open sea	-0.083	0.0211	0.000078	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13032736	chr14:50506638	14	50506638	LINC01599	Open sea	-0.054	0.0137	0.000078	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02368064	chr17:66342776	17	66342776	ARSG	Open sea	0.058	0.0147	0.000078	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08945450	chr1:11795905	1	11795905	AGTRAP	North shore	-0.077	0.0195	0.000079	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23206325	chr1:78353422	1	78353422	NEXN	North shore	0.057	0.0143	0.000079	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14592638	chr15:31749573	15	31749573	-	South shelf	-0.073	0.0185	0.000079	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg14562983	chr8:144348486	8	144348486	GLI4	North shore	-0.07	0.0176	0.000079	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg21567649	chr2:43245642	2	43245642	-	Open sea	-0.11	0.0268	0.00008	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05693489	chr6:32813441	6	32813441	TAP1;PSMB8	South shore	0.062	0.0157	0.00008	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02914427	chr16:29674184	16	29674184	SPN	North shore	0.045	0.0114	0.00008	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09836210	chr3:111436353	3	111436353	PLCXD2	Open sea	-0.1	0.0259	0.000081	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04101194	chr4:25656865	4	25656865	SLC34A2	North shore	0.058	0.0148	0.000082	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg24598922	chr6:144143992	6	144143992	PHACTR2	Open sea	-0.075	0.0191	0.000082	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25162548	chr19:37664126	19	37664126	ZNF585A	Open sea	-0.064	0.0163	0.000082	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20638127	chr6:31023286	6	31023286	HCG22	Open sea	-0.056	0.0143	0.000083	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09403020	chr10:50061892	10	50061892	WDFY4	Open sea	-0.065	0.0166	0.000083	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25899902	chr17:36773583	17	36773583	-	Open sea	0.097	0.0248	0.000084	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03769161	chr5:40486715	5	40486715	-	Open sea	0.056	0.0141	0.000084	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06868502	chr2:114517017	2	114517017	-	South shelf	0.06	0.0152	0.000085	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04783450	chr6:42068088	6	42068088	-	North shelf	-0.088	0.0225	0.000085	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16415646	chr7:41743001	7	41743001	LOC285954;INHBA	North shelf	-0.065	0.0166	0.000085	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08015157	chr17:29922345	17	29922345	-	Open sea	-0.052	0.0132	0.000085	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04303590	chr6:116890539	6	116890539	-	North shore	-0.049	0.0123	0.000086	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20647690	chr13:107191808	13	107191808	-	South shelf	-0.056	0.0143	0.000087	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg05555380	chr4:169853902	4	169853902	-	Open sea	-0.067	0.0171	0.000087	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04773587	chr1:206736644	1	206736644	RASSF5	Open sea	0.052	0.0132	0.000088	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27123351	chr11:67442249	11	67442249	ALDH3B2	Open sea	-0.093	0.0237	0.000089	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23507521	chr18:3246932	18	3246932	MYL12A	North shore	0.058	0.0149	0.000089	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg17737888	chr8:25337489	8	25337489	CDCA2	Open sea	-0.057	0.0144	0.000089	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08381578	chr8:77493912	8	77493912	-	Open sea	0.044	0.0112	0.00009	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15178529	chr2:28601340	2	28601340	-	Open sea	-0.089	0.0226	0.00009	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09326079	chr2:238107402	2	238107402	-	Open sea	-0.066	0.0169	0.000091	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg01129246	chr4:43032307	4	43032307	GRXCR1	Open sea	-0.046	0.0117	0.000091	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09139549	chr10:3151710	10	3151710	PFKP	South shelf	-0.057	0.0147	0.000091	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg20403938	chr12:54377457	12	54377457	HOXC10	North shore	0.058	0.0149	0.000091	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22825202	chr14:77767650	14	77767650	POMT2	Open sea	-0.12	0.0303	0.000091	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg04672210	chr15:99057794	15	99057794	FAM169B	Open sea	-0.069	0.0176	0.000091	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg22251773	chr10:104988200	10	104988200	-	Open sea	-0.074	0.0189	0.000091	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06889339	chr6:168197625	6	168197625	C6orf123	Island	0.047	0.0121	0.000092	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07177816	chr9:116647696	9	116647696	ZNF618	Open sea	-0.07	0.0178	0.000092	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg12398213	chr22:48872890	22	48872890	-	Open sea	-0.074	0.0189	0.000092	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg25804401	chr11:120893992	11	120893992	TBCEL	North shore	-0.1	0.0266	0.000092	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03176550	chr16:28996329	16	28996329	LAT	Open sea	0.058	0.015	0.000094	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg08420923	chr16:89436447	16	89436447	ANKRD11	North shelf	-0.091	0.0233	0.000094	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09078293	chr16:17510730	16	17510730	XYLT1	Open sea	0.068	0.0175	0.000094	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15004716	chr19:51944830	19	51944830	-	Open sea	0.061	0.0157	0.000094	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02700359	chr21:19153027	21	19153027	C21orf91-OT1	Open sea	0.041	0.0106	0.000094	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg13178361	chr1:162532502	1	162532502	UAP1	South shore	-0.081	0.0207	0.000096	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg07329296	chr20:60882647	20	60882647	ADRM1	Island	-0.06	0.0153	0.000096	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg15208638	chr14:73739337	14	73739337	PAPLN	Open sea	-0.11	0.0276	0.000096	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg16484195	chr2:204292045	2	204292045	ABI2	Open sea	-0.071	0.0181	0.000097	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27030688	chr11:106577062	11	106577062	GUCY1A2	Open sea	-0.04	0.0103	0.000097	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg23171477	chr2:135922344	2	135922344	RAB3GAP1	Open sea	-0.067	0.0173	0.000097	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27526774	chr1:235099089	1	235099089	-	Open sea	0.045	0.0115	0.000098	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg26971427	chr17:58887548	17	58887548	BCAS3	Open sea	0.086	0.0221	0.000098	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg06365976	chr16:89462292	16	89462292	ANKRD11	Open sea	-0.053	0.0136	0.000099	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg09991470	chr16:1207623	16	1207623	CACNA1H	Island	-0.066	0.017	0.000099	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg02638078	chr7:75164203	7	75164203	HIP1	Open sea	-0.077	0.0197	0.000099	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg03174319	chr2:28582155	2	28582155	-	Open sea	0.055	0.0141	0.000099	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model