author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-3.431	0.337	0	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-3.199	0.255	0	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-5.369	0.341	0	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-2.564	0.254	0	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-3.798	0.319	0	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	2542	1	66.3	Both	None	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-6.159	0.405	4e-52	-	28173150_serum_highdensity_lipoprotein_cholesterol_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0007165	5.21e-05	5.47e-43	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0006171	4.51e-05	1.17e-42	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-0.0004296	3.32e-05	2.27e-38	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	2542	1	66.3	Both	None	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-4.048	0.329	8.199999999999999e-35	-	28173150_serum_highdensity_lipoprotein_cholesterol_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-0.0004589	3.74e-05	1.2e-34	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0006421	5.53e-05	3.23e-31	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	2542	1	66.3	Both	None	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-4.54	0.397	2.8000000000000002e-30	-	28173150_serum_highdensity_lipoprotein_cholesterol_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	0.0005442	4.77e-05	3.38e-30	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	2542	1	66.3	Both	None	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-3.218	0.334	5.1e-22	-	28173150_serum_highdensity_lipoprotein_cholesterol_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-0.0003315	3.48e-05	1.5300000000000002e-21	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-0.0002449	2.64e-05	2.01e-20	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-0.0003628	3.93e-05	2.48e-20	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	2542	1	66.3	Both	None	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-3.762	0.408	3.1e-20	-	28173150_serum_highdensity_lipoprotein_cholesterol_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-0.0002816	3.18e-05	9.34e-19	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	-0.0003154	3.85e-05	2.67e-16	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	-0.0002678	3.34e-05	0.00000000000000101	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-2.072	0.262	0.0000000000000024	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	2.466	0.319	0.0000000000000098	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg07814318	chr15:31624584	15	31624584	KLF13	South shelf	-0.0003407	4.56e-05	0.0000000000000765	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg06560379	chr6:44231305	6	44231305	NFKBIE	North shore	0.0001023	1.38e-05	0.000000000000138	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg19273683	chr1:21656047	1	21656047	ECE1	Open sea	-0.0002921	4.03e-05	0.000000000000412	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	2542	1	66.3	Both	None	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-2.382	0.331	0.00000000000065	-	28173150_serum_highdensity_lipoprotein_cholesterol_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	-0.0002752	3.86e-05	0.000000000000956	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-0.0002176	3.08e-05	0.00000000000166	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-0.0001971	2.79e-05	0.00000000000168	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg04577162	chr7:73667397	7	73667397	RFC2	North shore	-0.0002327	3.34e-05	0.0000000000032	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg16407699	chr10:74020428	10	74020428	-	North shore	-0.0002751	3.95e-05	0.00000000000341	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg26804423	chr7:8201134	7	8201134	ICA1	Open sea	-0.0002052	2.96e-05	0.00000000000408	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg09572125	chr6:33400477	6	33400477	SYNGAP1	Open sea	-3.797	0.548	0.0000000000042	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg01101459	chr1:234871477	1	234871477	-	Open sea	-0.0002434	3.51e-05	0.00000000000439	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg09572125	chr6:33400477	6	33400477	SYNGAP1	Open sea	-3.915	0.567	0.0000000000051	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg06397161	chr22:39760059	22	39760059	SYNGR1	Open sea	-0.0002785	4.04e-05	0.00000000000564	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg19351166	chr2:209133632	2	209133632	PIKFYVE	South shelf	-0.0002253	3.27e-05	0.00000000000587	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg03676485	chr7:2563816	7	2563816	LFNG	Island	-0.0002281	3.34e-05	0.00000000000905	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg26804423	chr7:8201134	7	8201134	ICA1	Open sea	-0.0002296	3.38e-05	0.0000000000116	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg00567854	chr1:203273693	1	203273693	BTG2	North shore	-0.000259	3.84e-05	0.0000000000153	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg01944226	chr17:80188056	17	80188056	SLC16A3	Island	-0.0002115	3.14e-05	0.0000000000156	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg02855207	chr11:73087016	11	73087016	RELT	North shore	-0.0002495	3.71e-05	0.000000000017	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-0.0002228	3.37e-05	0.0000000000372	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg25667998	chr19:56705433	19	56705433	ZSCAN5B	North shelf	-0.0001708	2.58e-05	0.000000000039	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg27394566	chr14:105391635	14	105391635	PLD4	Open sea	-0.0002441	3.7e-05	0.00000000004	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg01944226	chr17:80188056	17	80188056	SLC16A3	Island	-0.0001776	2.69e-05	0.00000000004	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg01101459	chr1:234871477	1	234871477	-	Open sea	-0.000281	4.26e-05	0.0000000000422	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	0.0003847	5.84e-05	0.0000000000449	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	0.000299	4.55e-05	0.0000000000513	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg02879453	chr16:50321818	16	50321818	ADCY7	Open sea	-0.0002511	3.83e-05	0.0000000000553	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg06560379	chr6:44231305	6	44231305	NFKBIE	North shore	0.0001136	1.74e-05	0.0000000000605	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg07814318	chr15:31624584	15	31624584	KLF13	South shelf	-0.0003218	4.92e-05	0.0000000000638	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg02578470	chr3:127320670	3	127320670	MCM2	North shelf	-0.0002565	3.93e-05	0.0000000000656	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	ch.2.101965435R	chr2:102599003	2	102599003	-	Open sea	2.263	0.346	0.000000000066	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	-0.0002962	4.54e-05	0.0000000000666	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg05295703	chr2:102895712	2	102895712	-	Open sea	-0.0001871	2.87e-05	0.0000000000673	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg07567724	chr1:153777721	1	153777721	GATAD2B	Open sea	-0.0002617	4.01e-05	0.0000000000684	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg04577162	chr7:73667397	7	73667397	RFC2	North shore	-0.0002437	3.74e-05	0.0000000000694	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg02879453	chr16:50321818	16	50321818	ADCY7	Open sea	-0.0003016	4.62e-05	0.0000000000694	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg03676485	chr7:2563816	7	2563816	LFNG	Island	-0.0002447	3.75e-05	0.0000000000721	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg19273683	chr1:21656047	1	21656047	ECE1	Open sea	-0.000311	4.8e-05	0.0000000000899	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg19273683	chr1:21656047	1	21656047	ECE1	Open sea	-0.0002757	4.27e-05	0.000000000107	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg25739715	chr22:30663881	22	30663881	OSM	Open sea	0.0001291	2.01e-05	0.000000000134	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg14473904	chr15:93465087	15	93465087	CHD2	Open sea	-0.0001538	2.4e-05	0.000000000148	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg00567854	chr1:203273693	1	203273693	BTG2	North shore	-0.0002606	4.07e-05	0.000000000157	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg02855207	chr11:73087016	11	73087016	RELT	North shore	-0.0002529	3.96e-05	0.000000000163	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17485681	chr10:73565625	10	73565625	CDH23	Island	-0.0003368	5.27e-05	0.00000000017	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg17485681	chr10:73565625	10	73565625	CDH23	Island	-0.0002798	4.4e-05	0.000000000203	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg25889918	chr2:179916184	2	179916184	-	Open sea	-0.0002496	3.93e-05	0.000000000207	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg09777883	chr11:112093696	11	112093696	-	North shelf	-0.0002152	3.39e-05	0.000000000209	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg09613192	chr2:181388538	2	181388538	-	Open sea	-0.0003163	4.98e-05	0.000000000221	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	-0.0003076	4.85e-05	0.000000000224	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg18034719	chr5:176860863	5	176860863	GRK6	Island	0.0001683	2.65e-05	0.000000000226	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg15551881	chr9:123688715	9	123688715	TRAF1	North shelf	-0.0003127	4.95e-05	0.000000000259	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg13522406	chr6:30581820	6	30581820	PPP1R10	North shelf	-0.0001987	3.14e-05	0.00000000026	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg19881557	chr14:20967426	14	20967426	-	Open sea	-0.0003045	4.82e-05	0.000000000263	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg21113318	chr14:92983645	14	92983645	RIN3	South shelf	-0.0002177	3.45e-05	0.000000000273	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg25889918	chr2:179916184	2	179916184	-	Open sea	-0.0002133	3.38e-05	0.000000000287	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg02855207	chr11:73087016	11	73087016	RELT	North shore	-0.0002023	3.21e-05	0.000000000314	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg01130991	chr17:46510392	17	46510392	-	South shelf	-0.0002555	4.06e-05	0.000000000323	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg04934530	chr22:47080171	22	47080171	-	North shore	-0.0002308	3.68e-05	0.000000000358	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg07175797	chr16:50317656	16	50317656	-	Open sea	-0.0001749	2.8e-05	0.00000000039	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg21486834	chr17:74477542	17	74477542	RHBDF2	South shelf	-0.0001988	3.18e-05	0.000000000413	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg13821176	chr8:126448338	8	126448338	TRIB1	South shelf	-0.0002374	3.81e-05	0.000000000445	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg01130991	chr17:46510392	17	46510392	-	South shelf	-0.0002828	4.57e-05	0.000000000598	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg25130381	chr1:27440721	1	27440721	SLC9A1	Open sea	-0.00019	3.07e-05	0.00000000062	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg24678869	chr1:153919638	1	153919638	DENND4B	South shore	-0.0001562	2.53e-05	0.000000000639	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg13222915	chr1:184598594	1	184598594	-	Open sea	0.0002201	3.56e-05	0.000000000642	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg22753611	chr6:17472892	6	17472892	CAP2	Open sea	-0.0002218	3.6e-05	0.00000000069	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg12269535	chr6:43142014	6	43142014	SRF	Island	0.0002378	3.86e-05	0.000000000713	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg15551881	chr9:123688715	9	123688715	TRAF1	North shelf	-0.0002646	4.3e-05	0.000000000733	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg25667998	chr19:56705433	19	56705433	ZSCAN5B	North shelf	-0.0001836	2.99e-05	0.000000000802	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg21486834	chr17:74477542	17	74477542	RHBDF2	South shelf	-0.000172	2.8e-05	0.000000000846	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	-0.0004737	7.73e-05	0.000000000892	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg18034719	chr5:176860863	5	176860863	GRK6	Island	0.0001798	2.94e-05	0.000000000901	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg10717869	chr1:205780912	1	205780912	SLC41A1	North shore	-0.0001823	2.99e-05	0.00000000102	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg02578470	chr3:127320670	3	127320670	MCM2	North shelf	-0.0002542	4.16e-05	0.00000000102	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg27394566	chr14:105391635	14	105391635	PLD4	Open sea	-0.0002649	4.35e-05	0.00000000113	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	-0.0002477	4.07e-05	0.00000000118	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg19638572	chr1:206733139	1	206733139	RASSF5	South shelf	-0.0002115	3.48e-05	0.00000000128	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg24678869	chr1:153919638	1	153919638	DENND4B	South shore	-0.0001688	2.78e-05	0.00000000129	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg02578470	chr3:127320670	3	127320670	MCM2	North shelf	-0.000269	4.45e-05	0.00000000148	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg12315466	chr2:233923814	2	233923814	INPP5D	North shore	-0.0001629	2.7e-05	0.00000000164	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg07175797	chr16:50317656	16	50317656	-	Open sea	-0.000186	3.09e-05	0.0000000017	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg03676485	chr7:2563816	7	2563816	LFNG	Island	-0.0002141	3.55e-05	0.00000000172	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg12315466	chr2:233923814	2	233923814	INPP5D	North shore	-0.0001798	2.99e-05	0.00000000174	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg18952506	chr20:19916087	20	19916087	RIN2	Open sea	-0.0001513	2.52e-05	0.00000000187	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg12825509	chr3:185648568	3	185648568	TRA2B	Open sea	-0.0002831	4.71e-05	0.00000000191	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg14352682	chr6:30614168	6	30614168	C6orf136	North shore	-0.0001771	2.95e-05	0.00000000192	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg13222915	chr1:184598594	1	184598594	-	Open sea	0.00019	3.17e-05	0.00000000197	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg02855207	chr11:73087016	11	73087016	RELT	North shore	-0.0002049	3.42e-05	0.00000000198	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	-0.0002578	4.3e-05	0.00000000204	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg21042285	chr13:23954979	13	23954979	SACS	Open sea	-0.0001789	2.99e-05	0.0000000021	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg00567854	chr1:203273693	1	203273693	BTG2	North shore	-0.0002593	4.33e-05	0.00000000216	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg09777883	chr11:112093696	11	112093696	-	North shelf	-0.0002322	3.88e-05	0.0000000022	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg12825509	chr3:185648568	3	185648568	TRA2B	Open sea	-0.0003218	5.4e-05	0.00000000258	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg21042285	chr13:23954979	13	23954979	SACS	Open sea	-0.0001541	2.61e-05	0.00000000366	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	1.599	0.271	0.0000000037	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg12269535	chr6:43142014	6	43142014	SRF	Island	0.0002646	4.49e-05	0.00000000391	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg10183965	chr17:3824497	17	3824497	-	North shelf	-0.0002318	3.94e-05	0.00000000406	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-0.0002133	3.63e-05	0.00000000419	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg13729116	chr4:1859262	4	1859262	LETM1	South shore	-0.0001952	3.32e-05	0.00000000428	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg04934530	chr22:47080171	22	47080171	-	North shore	-0.0002463	4.2e-05	0.00000000441	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	-0.0002819	4.81e-05	0.00000000475	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg10183965	chr17:3824497	17	3824497	-	North shelf	-0.0002105	3.59e-05	0.00000000475	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg25402049	chr1:14029875	1	14029875	PRDM2	South shelf	-0.0002037	3.48e-05	0.00000000495	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg13821176	chr8:126448338	8	126448338	TRIB1	South shelf	-0.000251	4.3e-05	0.00000000541	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg19742105	chr5:88426429	5	88426429	-	Open sea	0.0001543	2.65e-05	0.0000000061	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg00567854	chr1:203273693	1	203273693	BTG2	North shore	-0.0002681	4.61e-05	0.00000000614	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg23580000	chr16:50322156	16	50322156	ADCY7	Open sea	-0.0002669	4.6e-05	0.00000000638	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg23580000	chr16:50322156	16	50322156	ADCY7	Open sea	-0.000231	3.98e-05	0.00000000642	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg04181189	chr11:129817418	11	129817418	PRDM10	Open sea	-0.0001715	2.96e-05	0.0000000067	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg16407699	chr10:74020428	10	74020428	-	North shore	-0.0002801	4.84e-05	0.0000000073	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg04548926	chr11:2219053	11	2219053	-	Open sea	-0.0001694	2.93e-05	0.00000000742	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg13622265	chr9:124584474	9	124584474	TTLL11	Open sea	-0.0003095	5.36e-05	0.00000000777	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg06897661	chr16:50322074	16	50322074	ADCY7	Open sea	-0.0002504	4.35e-05	0.0000000087	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg13522406	chr6:30581820	6	30581820	PPP1R10	North shelf	-0.000202	3.51e-05	0.00000000884	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg17992670	chr19:11216306	19	11216306	LDLR	Island	-0.0001337	2.33e-05	0.00000000908	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg18520125	chr13:28903926	13	28903926	FLT1	Open sea	-0.0002279	3.97e-05	0.00000000939	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg12728588	chr1:36025489	1	36025489	NCDN	South shore	-0.0001282	2.24e-05	0.0000000103	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg03676485	chr7:2563816	7	2563816	LFNG	Island	-0.0002291	4e-05	0.0000000106	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg24939194	chr7:2563611	7	2563611	LFNG	Island	-0.0001575	2.76e-05	0.0000000113	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg25739016	chr1:167638918	1	167638918	RCSD1	Open sea	-0.0001863	3.26e-05	0.0000000116	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg09121543	chr17:61774794	17	61774794	LIMD2	North shelf	-0.000226	3.97e-05	0.000000012	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg14473904	chr15:93465087	15	93465087	CHD2	Open sea	-0.0001503	2.64e-05	0.0000000129	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg16655795	chr19:42897238	19	42897238	-	North shelf	-0.0001853	3.26e-05	0.0000000134	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg26804423	chr7:8201134	7	8201134	ICA1	Open sea	-0.0002046	3.6e-05	0.0000000136	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg21113318	chr14:92983645	14	92983645	RIN3	South shelf	-0.00017	3e-05	0.0000000139	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg13622265	chr9:124584474	9	124584474	TTLL11	Open sea	-0.0002474	4.36e-05	0.0000000143	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg19273683	chr1:21656047	1	21656047	ECE1	Open sea	-0.0002894	5.11e-05	0.000000015	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg26002370	chr10:73596857	10	73596857	PSAP	Open sea	-0.0001557	2.76e-05	0.000000016	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg26446803	chr11:1807232	11	1807232	-	Open sea	-0.0002142	3.79e-05	0.0000000161	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg10179300	chr5:14147618	5	14147618	TRIO	South shelf	-0.0002174	3.85e-05	0.0000000167	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg03339817	chr2:128458281	2	128458281	SFT2D3	North shore	-0.0001582	2.8e-05	0.0000000169	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg24694018	chr1:145457621	1	145457621	POLR3GL	Open sea	0.0001793	3.18e-05	0.0000000178	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg02902261	chr7:72991150	7	72991150	TBL2	North shore	-3.004	0.533	0.000000018	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg25551219	chr22:50909865	22	50909865	SBF1	North shelf	-0.0001656	2.94e-05	0.0000000181	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg02578470	chr3:127320670	3	127320670	MCM2	North shelf	-0.0002654	4.73e-05	0.0000000206	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg12728588	chr1:36025489	1	36025489	NCDN	South shore	-0.000144	2.57e-05	0.0000000216	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg01676795	chr7:75586348	7	75586348	POR	Open sea	-0.0002542	4.54e-05	0.0000000216	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg14352682	chr6:30614168	6	30614168	C6orf136	North shore	-0.0001492	2.67e-05	0.0000000217	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg05295703	chr2:102895712	2	102895712	-	Open sea	-0.0001864	3.33e-05	0.0000000221	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg25402049	chr1:14029875	1	14029875	PRDM2	South shelf	-0.0002224	3.98e-05	0.0000000226	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg00108715	chr3:52565015	3	52565015	NT5DC2	North shore	-0.0002099	3.76e-05	0.0000000238	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg24065451	chr11:128419512	11	128419512	ETS1	Island	-0.0002711	4.86e-05	0.0000000245	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg05264101	chr17:75880308	17	75880308	FLJ45079	North shelf	-0.0001772	3.18e-05	0.0000000247	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg03339817	chr2:128458281	2	128458281	SFT2D3	North shore	-0.0001347	2.42e-05	0.0000000249	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg15551881	chr9:123688715	9	123688715	TRAF1	North shelf	-0.0002927	5.26e-05	0.000000026	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg15551881	chr9:123688715	9	123688715	TRAF1	North shelf	-0.0002533	4.55e-05	0.0000000261	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	2.827	0.509	0.000000028	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg11849692	chr10:103875969	10	103875969	LDB1	North shelf	-0.0001543	2.78e-05	0.0000000286	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg14633721	chr17:8869864	17	8869864	PIK3R5	South shore	-0.0001996	3.6e-05	0.0000000291	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg26804423	chr7:8201134	7	8201134	ICA1	Open sea	-0.0001739	3.14e-05	0.0000000298	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg13729116	chr4:1859262	4	1859262	LETM1	South shore	-0.0001626	2.94e-05	0.0000000303	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg07730360	chr3:128845626	3	128845626	-	Open sea	-0.0002034	3.67e-05	0.0000000308	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-3.475	0.628	0.000000031	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg18952506	chr20:19916087	20	19916087	RIN2	Open sea	-0.0001683	3.04e-05	0.0000000315	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg03014634	chr16:85205030	16	85205030	-	Island	-0.0001986	3.59e-05	0.0000000317	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg16609995	chr6:32159036	6	32159036	PBX2;GPSM3	Open sea	-0.0001989	3.6e-05	0.0000000323	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg22753611	chr6:17472892	6	17472892	CAP2	Open sea	-0.0002432	4.4e-05	0.0000000324	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg02717339	chr2:97524767	2	97524767	ANKRD39	South shore	-0.0002843	5.15e-05	0.0000000327	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg00108715	chr3:52565015	3	52565015	NT5DC2	North shore	-0.000172	3.12e-05	0.0000000339	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	0.0001166	2.11e-05	0.0000000344	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg12866859	chr17:43224332	17	43224332	HEXIM1	North shore	-0.0001654	3e-05	0.0000000365	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg01944226	chr17:80188056	17	80188056	SLC16A3	Island	-0.0001835	3.34e-05	0.0000000376	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg00870514	chr17:29717946	17	29717946	RAB11FIP4	North shore	-0.0003865	7.03e-05	0.0000000379	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg07567724	chr1:153777721	1	153777721	GATAD2B	Open sea	-0.0002484	4.52e-05	0.0000000381	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg09581649	chr16:4572735	16	4572735	C16orf5	Open sea	-0.0001467	2.67e-05	0.0000000385	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg24002003	chr15:101668143	15	101668143	-	Open sea	0.0002057	3.75e-05	0.0000000406	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	-0.0005012	9.14e-05	0.0000000412	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg09199486	chr17:48259448	17	48259448	-	Open sea	-0.000128	2.33e-05	0.0000000415	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg19351166	chr2:209133632	2	209133632	PIKFYVE	South shelf	-0.0002072	3.78e-05	0.0000000416	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg01856529	chr12:54653091	12	54653091	CBX5	Open sea	-0.0002209	4.03e-05	0.0000000417	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg22257056	chr3:32462766	3	32462766	CMTM7	Open sea	-0.0001475	2.69e-05	0.0000000419	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg02717339	chr2:97524767	2	97524767	ANKRD39	South shore	-0.0002327	4.25e-05	0.000000042	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg11849692	chr10:103875969	10	103875969	LDB1	North shelf	-0.0001648	3.01e-05	0.0000000445	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg09121543	chr17:61774794	17	61774794	LIMD2	North shelf	-0.0001893	3.46e-05	0.0000000446	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	2542	1	66.3	Both	None	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	2.234	0.408	0.000000045	-	28173150_serum_highdensity_lipoprotein_cholesterol_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg24694018	chr1:145457621	1	145457621	POLR3GL	Open sea	0.000203	3.72e-05	0.0000000479	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg07730360	chr3:128845626	3	128845626	-	Open sea	-0.0001759	3.22e-05	0.0000000484	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg04383058	chr11:67273507	11	67273507	PITPNM1	North shore	-0.000165	3.03e-05	0.0000000495	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg04383058	chr11:67273507	11	67273507	PITPNM1	North shore	-0.0002083	3.82e-05	0.0000000496	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg15821562	chr14:90083275	14	90083275	FOXN3	North shelf	-0.0002007	3.68e-05	0.0000000511	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg25130381	chr1:27440721	1	27440721	SLC9A1	Open sea	-0.0001838	3.38e-05	0.0000000526	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17485681	chr10:73565625	10	73565625	CDH23	Island	-0.0003053	5.61e-05	0.0000000526	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg20732160	chr3:48590040	3	48590040	PFKFB4	North shelf	-0.0001823	3.35e-05	0.0000000529	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg10717869	chr1:205780912	1	205780912	SLC41A1	North shore	-0.000182	3.35e-05	0.0000000536	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg04548926	chr11:2219053	11	2219053	-	Open sea	-0.0001434	2.64e-05	0.0000000546	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg25551219	chr22:50909865	22	50909865	SBF1	North shelf	-0.0001408	2.6e-05	0.0000000582	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg03699074	chr16:88849875	16	88849875	FAM38A	North shore	0.0002133	3.94e-05	0.0000000595	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg25739016	chr1:167638918	1	167638918	RCSD1	Open sea	-0.0001984	3.66e-05	0.0000000605	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg20782117	chr7:95865631	7	95865631	SLC25A13	Open sea	0.0002628	4.86e-05	0.0000000634	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg00959259	chr3:122281975	3	122281975	PARP9;DTX3L	North shore	2.342	0.434	0.000000066	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg18520125	chr13:28903926	13	28903926	FLT1	Open sea	-0.0002512	4.65e-05	0.0000000678	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg26313301	chr19:11219615	19	11219615	LDLR	South shelf	-0.0001303	2.41e-05	0.0000000679	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg08788930	chr8:142201685	8	142201685	DENND3	Open sea	-0.0002253	4.18e-05	0.0000000685	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg09613192	chr2:181388538	2	181388538	-	Open sea	-0.0003264	6.05e-05	0.0000000687	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg13305415	chr5:141697464	5	141697464	SPRY4	Open sea	-0.0003008	5.59e-05	0.0000000725	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg06397161	chr22:39760059	22	39760059	SYNGR1	Open sea	-0.0002585	4.8e-05	0.0000000725	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg04181189	chr11:129817418	11	129817418	PRDM10	Open sea	-0.0001369	2.54e-05	0.0000000727	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg01751802	chr19:11309639	19	11309639	KANK2	South shore	-0.0002525	4.69e-05	0.0000000737	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg01751802	chr19:11309639	19	11309639	KANK2	South shore	-0.0002147	3.99e-05	0.0000000749	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg05720226	chr7:116786597	7	116786597	ST7;ST7OT2	Open sea	-0.0002091	3.89e-05	0.000000078	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg09199486	chr17:48259448	17	48259448	-	Open sea	-0.0001132	2.11e-05	0.0000000864	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg01676795	chr7:75586348	7	75586348	POR	Open sea	-0.0002763	5.16e-05	0.0000000865	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1583	2	57	Both	None	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	-0.0002829	5.29e-05	0.0000000895	-	28213390_serum_highdensity_lipoprotein_cholesterol_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17992670	chr19:11216306	19	11216306	LDLR	Island	-0.0001435	2.68e-05	0.0000000897	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for BMI	Table S7	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg14352682	chr6:30614168	6	30614168	C6orf136	North shore	-0.0001678	3.14e-05	0.0000000913	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg16609995	chr6:32159036	6	32159036	PBX2;GPSM3	Open sea	-0.0001659	3.11e-05	0.0000000926	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg09581649	chr16:4572735	16	4572735	C16orf5	Open sea	-0.0001597	2.99e-05	0.0000000931	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg19638572	chr1:206733139	1	206733139	RASSF5	South shelf	-0.0002171	4.07e-05	0.0000000949	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg19566658	chr7:100466241	7	100466241	TRIP6	South shelf	-0.0002643	4.96e-05	0.0000000972	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg26002370	chr10:73596857	10	73596857	PSAP	Open sea	-0.0001275	2.39e-05	0.0000000972	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg24939194	chr7:2563611	7	2563611	LFNG	Island	-0.0001621	3.05e-05	0.000000104	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg18192491	chr6:114384871	6	114384871	HS3ST5	Open sea	0.0002542	4.78e-05	0.000000105	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg14468090	chr3:129032864	3	129032864	-	North shore	-0.0001812	3.41e-05	0.000000106	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg22799757	chr7:29997642	7	29997642	SCRN1	Open sea	0.0001767	3.33e-05	0.000000108	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg19742105	chr5:88426429	5	88426429	-	Open sea	0.0001271	2.42e-05	0.000000142	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg01944226	chr17:80188056	17	80188056	SLC16A3	Island	-0.0001492	2.85e-05	0.000000165	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg08549335	chr7:30387954	7	30387954	ZNRF2	Open sea	1.635	0.313	0.00000017	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg05720226	chr7:116786597	7	116786597	ST7;ST7OT2	Open sea	-0.0001604	3.07e-05	0.000000178	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg13305415	chr5:141697464	5	141697464	SPRY4	Open sea	-0.0002355	4.52e-05	0.000000193	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg17485681	chr10:73565625	10	73565625	CDH23	Island	-0.0002426	4.66e-05	0.000000193	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg15821562	chr14:90083275	14	90083275	FOXN3	North shelf	-0.0001718	3.3e-05	0.000000199	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	2542	1	66.3	Both	None	cg09572125	chr6:33400477	6	33400477	SYNGAP1	Open sea	-3.647	0.702	0.00000021	-	28173150_serum_highdensity_lipoprotein_cholesterol_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1583	2	57	Both	None	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	-0.0003287	6.34e-05	0.00000022	-	28213390_serum_highdensity_lipoprotein_cholesterol_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg24002003	chr15:101668143	15	101668143	-	Open sea	0.0001684	3.25e-05	0.000000223	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg24065451	chr11:128419512	11	128419512	ETS1	Island	-0.0002047	3.96e-05	0.000000233	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg03339016	chr22:19279085	22	19279085	CLTCL1	Island	3.092	0.599	0.00000025	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg26446803	chr11:1807232	11	1807232	-	Open sea	-0.0001673	3.25e-05	0.000000259	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	2542	1	66.3	Both	None	cg09572125	chr6:33400477	6	33400477	SYNGAP1	Open sea	-3.716	0.729	0.00000034	-	28173150_serum_highdensity_lipoprotein_cholesterol_replication_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg16411857	chr16:57023191	16	57023191	NLRC5	Island	2.459	0.485	0.0000004	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg27342720	chr8:120033982	8	120033982	-	Open sea	3.356	0.664	0.00000043	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg27338287	chr3:190580644	3	190580644	LOC647309	Island	-2.812	0.557	0.00000045	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg18659867	chr10:80007739	10	80007739	-	Open sea	3.881	0.772	0.0000005	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg08788930	chr8:142201685	8	142201685	DENND3	Open sea	-0.0001919	3.83e-05	0.000000531	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg05264101	chr17:75880308	17	75880308	FLJ45079	North shelf	-0.0001461	2.92e-05	0.000000561	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg27342720	chr8:120033982	8	120033982	-	Open sea	1.915	0.387	0.00000072	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg16655795	chr19:42897238	19	42897238	-	North shelf	-0.0001406	2.84e-05	0.000000726	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg19126110	chr7:115263754	7	115263754	-	Open sea	2.45	0.495	0.00000075	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg06897661	chr16:50322074	16	50322074	ADCY7	Open sea	-0.0001763	3.62e-05	0.0000011	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg22257056	chr3:32462766	3	32462766	CMTM7	Open sea	-0.0001168	2.4e-05	0.00000113	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg03838769	chr4:168156467	4	168156467	SPOCK3	South shore	2.234	0.46	0.0000012	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg13613180	chr11:74560694	11	74560694	XRRA1	Open sea	-1.53	0.315	0.0000012	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for BMI	Table S8	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	65	Both	None	cg14352682	chr6:30614168	6	30614168	C6orf136	North shore	-0.0001373	2.83e-05	0.00000121	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg03699074	chr16:88849875	16	88849875	FAM38A	North shore	0.0001531	3.16e-05	0.00000127	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg03014634	chr16:85205030	16	85205030	-	Island	-0.0001534	3.2e-05	0.00000159	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg18192491	chr6:114384871	6	114384871	HS3ST5	Open sea	0.000186	3.88e-05	0.00000164	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-1.925	0.403	0.0000017	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg20312179	chr1:51981505	1	51981505	EPS15	North shelf	2.603	0.548	0.000002	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg12669088	chr12:25541364	12	25541364	-	South shore	4.101	0.862	0.000002	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg26561196	chr16:68344680	16	68344680	SLC7A6OS;PRMT7	Island	2.559	0.54	0.0000022	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg03555914	chr2:121554810	2	121554810	GLI2	Open sea	-3.269	0.692	0.0000023	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	2542	1	66.3	Both	None	ch.2.101965435R	chr2:102599003	2	102599003	-	Open sea	2.06	0.436	0.0000023	-	28173150_serum_highdensity_lipoprotein_cholesterol_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg12866859	chr17:43224332	17	43224332	HEXIM1	North shore	-0.0001225	2.6e-05	0.00000239	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg14627538	chr21:48082402	21	48082402	PRMT2	South shore	-3.139	0.666	0.0000025	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg16743005	chr16:50403128	16	50403128	BRD7	Open sea	2.861	0.609	0.0000026	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg19881557	chr14:20967426	14	20967426	-	Open sea	-0.0001791	3.81e-05	0.00000265	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg08533242	chr20:62195615	20	62195615	PRIC285	Island	-2.375	0.506	0.0000027	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg14364472	chr9:139394549	9	139394549	NOTCH1	North shore	-2.061	0.44	0.0000029	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg09572125	chr6:33400477	6	33400477	SYNGAP1	Open sea	-4.222	0.903	0.000003	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg14468090	chr3:129032864	3	129032864	-	North shore	-0.0001402	3e-05	0.00000302	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg03128029	chr2:203143288	2	203143288	NOP58	Open sea	2.237	0.48	0.0000031	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg10415314	chr14:33949227	14	33949227	NPAS3	Open sea	1.841	0.395	0.0000031	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg27466042	chr17:36896370	17	36896370	PCGF2	Open sea	-2.354	0.507	0.0000034	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg07395004	chr1:1310147	1	1310147	AURKAIP1	Island	2.632	0.567	0.0000035	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg08549335	chr7:30387954	7	30387954	ZNRF2	Open sea	2.22	0.48	0.0000037	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg26313301	chr19:11219615	19	11219615	LDLR	South shelf	-9.41e-05	2.04e-05	0.00000384	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg09572125	chr6:33400477	6	33400477	SYNGAP1	Open sea	-4.029	0.876	0.0000042	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg03128029	chr2:203143288	2	203143288	NOP58	Open sea	3.611	0.785	0.0000043	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg01277372	chr3:169378764	3	169378764	MECOM	North shore	-3.079	0.671	0.0000044	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg07839457	chr16:57023022	16	57023022	NLRC5	North shore	2.212	0.482	0.0000044	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg26948596	chr14:93078627	14	93078627	RIN3	Open sea	-2.988	0.652	0.0000046	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg25736198	chr12:72345225	12	72345225	TPH2	Open sea	2.674	0.584	0.0000047	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	ch.2.101965435R	chr2:102599003	2	102599003	-	Open sea	2.61	0.57	0.0000048	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg03667621	chr7:1478715	7	1478715	MICALL2	Open sea	-2.75	0.601	0.0000048	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg14364472	chr9:139394549	9	139394549	NOTCH1	North shore	-1.934	0.423	0.0000048	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg08549335	chr7:30387954	7	30387954	ZNRF2	Open sea	1.324	0.29	0.0000051	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-2.438	0.537	0.0000057	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg10179300	chr5:14147618	5	14147618	TRIO	South shelf	-0.0001396	3.08e-05	0.00000572	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg12669088	chr12:25541364	12	25541364	-	South shore	2.514	0.555	0.0000058	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-2.718	0.6	0.0000058	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg22799757	chr7:29997642	7	29997642	SCRN1	Open sea	0.0001349	2.98e-05	0.00000611	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg20782117	chr7:95865631	7	95865631	SLC25A13	Open sea	0.0001858	4.14e-05	0.00000699	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg00959259	chr3:122281975	3	122281975	PARP9;DTX3L	North shore	1.881	0.419	0.0000071	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg14633721	chr17:8869864	17	8869864	PIK3R5	South shore	-0.0001379	3.07e-05	0.00000718	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg14758812	chr10:103090818	10	103090818	-	Open sea	2.331	0.519	0.0000072	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg27338287	chr3:190580644	3	190580644	LOC647309	Island	-2.249	0.501	0.0000073	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg10415314	chr14:33949227	14	33949227	NPAS3	Open sea	3.086	0.688	0.0000073	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg11827629	chr12:115822424	12	115822424	-	Open sea	2.897	0.646	0.0000074	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1583	2	57	Both	None	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-0.0003218	7.18e-05	0.00000743	-	28213390_serum_highdensity_lipoprotein_cholesterol_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg13613180	chr11:74560694	11	74560694	XRRA1	Open sea	-2.267	0.506	0.0000075	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg16838132	chr22:39913220	22	39913220	SMCR7L	North shelf	-1.722	0.385	0.0000078	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg25739715	chr22:30663881	22	30663881	OSM	Open sea	6.45e-05	1.44e-05	0.00000782	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	ch.2.101965435R	chr2:102599003	2	102599003	-	Open sea	1.173	0.263	0.0000081	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg02111504	chr5:93954110	5	93954110	C5orf36;ANKRD32	Island	2.753	0.617	0.0000081	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg25097801	chr8:23315147	8	23315147	ENTPD4	Island	2.23	0.5	0.0000084	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg07511188	chr12:51442144	12	51442144	LETMD1	Island	2.486	0.562	0.0000097	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg18942579	chr17:57915773	17	57915773	TMEM49	Open sea	2.289	0.517	0.0000097	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg08530041	chr5:168093430	5	168093430	SLIT3	Open sea	-2.776	0.628	0.0000098	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg02902261	chr7:72991150	7	72991150	TBL2	North shore	-1.757	0.398	0.00001	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg02902261	chr7:72991150	7	72991150	TBL2	North shore	-1.451	0.33	0.000011	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg03838769	chr4:168156467	4	168156467	SPOCK3	South shore	1.891	0.431	0.000012	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1583	2	57	Both	None	cg06397161	chr22:39760059	22	39760059	SYNGR1	Open sea	-0.0003273	7.5e-05	0.0000127	-	28213390_serum_highdensity_lipoprotein_cholesterol_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg00870514	chr17:29717946	17	29717946	RAB11FIP4	North shore	-0.000242	5.59e-05	0.0000152	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1583	2	57	Both	None	cg19351166	chr2:209133632	2	209133632	PIKFYVE	South shelf	-0.0002793	6.54e-05	0.0000196	-	28213390_serum_highdensity_lipoprotein_cholesterol_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	2542	1	66.3	Both	None	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	1.494	0.35	0.00002	-	28173150_serum_highdensity_lipoprotein_cholesterol_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-1.665	0.391	0.000021	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg16838132	chr22:39913220	22	39913220	SMCR7L	North shelf	-1.557	0.366	0.000021	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg19566658	chr7:100466241	7	100466241	TRIP6	South shelf	-0.0001624	3.83e-05	0.000022	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3889	4	63	Both	None	cg01856529	chr12:54653091	12	54653091	CBX5	Open sea	-0.0001418	3.39e-05	0.0000282	-	28213390_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg01277372	chr3:169378764	3	169378764	MECOM	North shore	-1.683	0.403	0.000029	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg27342720	chr8:120033982	8	120033982	-	Open sea	1.362	0.326	0.000029	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg10415314	chr14:33949227	14	33949227	NPAS3	Open sea	1.455	0.349	0.000031	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg07511188	chr12:51442144	12	51442144	LETMD1	Island	1.474	0.357	0.000036	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg07839457	chr16:57023022	16	57023022	NLRC5	North shore	1.946	0.475	0.000041	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	1.757	0.428	0.000041	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg14627538	chr21:48082402	21	48082402	PRMT2	South shore	-1.544	0.391	0.000079	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg13613180	chr11:74560694	11	74560694	XRRA1	Open sea	-1.068	0.271	0.000083	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg16411857	chr16:57023191	16	57023191	NLRC5	Island	1.634	0.416	0.000084	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg07395004	chr1:1310147	1	1310147	AURKAIP1	Island	1.414	0.36	0.000086	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Replication	Table S4	DNA methylation	Serum high-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1583	2	57	Both	None	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-0.0002286	5.83e-05	0.0000872	-	28213390_serum_highdensity_lipoprotein_cholesterol_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum high-density lipoprotein cholesterol	EFO_0004612, CHEBI_47775	Discovery and replication adjusted for surrogate variables	Table S1	Serum high-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg25736198	chr12:72345225	12	72345225	TPH2	Open sea	1.378	0.353	0.000095	-	28173150_serum_highdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables