author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg00285394	chr8:126011954	8	126011954	SQLE	South shore	0.000217	2.96e-05	0.000000000000221	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg00285394	chr8:126011954	8	126011954	SQLE	South shore	0.0002182	2.98e-05	0.00000000000023	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg20448706	chr14:32941841	14	32941841	AKAP6	Open sea	0.0001811	2.81e-05	0.000000000116	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg24378227	chr6:1396771	6	1396771	-	South shelf	0.0001979	3.08e-05	0.000000000136	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg24378227	chr6:1396771	6	1396771	-	South shelf	0.0001978	3.09e-05	0.000000000161	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg20448706	chr14:32941841	14	32941841	AKAP6	Open sea	0.0001788	2.8e-05	0.000000000181	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg00285394	chr8:126011954	8	126011954	SQLE	South shore	0.0002339	3.91e-05	0.00000000232	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg06621027	chr2:80179759	2	80179759	CTNNA2	Open sea	0.0001721	2.89e-05	0.00000000264	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg15705971	chr11:92110262	11	92110262	FAT3	Open sea	0.0001509	2.56e-05	0.00000000371	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg00285394	chr8:126011954	8	126011954	SQLE	South shore	0.0002295	3.9e-05	0.00000000412	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg03188976	chr7:134443864	7	134443864	-	Open sea	0.0001437	2.47e-05	0.00000000582	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg15705971	chr11:92110262	11	92110262	FAT3	Open sea	0.0001475	2.55e-05	0.00000000753	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg25436634	chr3:181045270	3	181045270	-	Open sea	0.0002596	4.5e-05	0.00000000779	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg03188976	chr7:134443864	7	134443864	-	Open sea	0.0001417	2.46e-05	0.00000000869	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg23759710	chr2:42990957	2	42990957	OXER1	Open sea	-8.95e-05	1.56e-05	0.00000000911	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg06621027	chr2:80179759	2	80179759	CTNNA2	Open sea	0.0001651	2.89e-05	0.0000000109	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg08261450	chr12:130384734	12	130384734	TMEM132D	North shelf	0.0001588	2.78e-05	0.0000000113	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg05897122	chr4:53112707	4	53112707	-	Open sea	0.0001779	3.12e-05	0.0000000123	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg25436634	chr3:181045270	3	181045270	-	Open sea	0.0002553	4.48e-05	0.0000000124	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg20525527	chr17:17056629	17	17056629	MPRIP	Open sea	-9.95e-05	1.75e-05	0.0000000136	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg08261450	chr12:130384734	12	130384734	TMEM132D	North shelf	0.0001584	2.79e-05	0.0000000137	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg23759710	chr2:42990957	2	42990957	OXER1	Open sea	-8.81e-05	1.55e-05	0.0000000145	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg26105227	chr11:17495097	11	17495097	ABCC8	North shelf	0.0001808	3.2e-05	0.0000000167	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg04999435	chr11:63230511	11	63230511	HRASLS5	Open sea	0.0001364	2.42e-05	0.0000000177	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg24378227	chr6:1396771	6	1396771	-	South shelf	0.000126	2.24e-05	0.0000000204	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg04999435	chr11:63230511	11	63230511	HRASLS5	Open sea	0.000109	1.95e-05	0.0000000231	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg04999435	chr11:63230511	11	63230511	HRASLS5	Open sea	0.0001356	2.43e-05	0.0000000234	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg12810800	chr2:159788345	2	159788345	-	Open sea	0.0001761	3.17e-05	0.0000000263	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg26105227	chr11:17495097	11	17495097	ABCC8	North shelf	0.0001785	3.21e-05	0.0000000279	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg20525527	chr17:17056629	17	17056629	MPRIP	Open sea	-9.77e-05	1.76e-05	0.0000000295	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg11001536	chr5:153489773	5	153489773	-	Open sea	0.0001798	3.26e-05	0.0000000347	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg16736826	chr1:41951512	1	41951512	EDN2	Open sea	9.9e-05	1.81e-05	0.0000000422	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg04999435	chr11:63230511	11	63230511	HRASLS5	Open sea	0.0001074	1.96e-05	0.0000000444	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg05337441	chr2:21266568	2	21266568	APOB	North shore	0.0002859	5.23e-05	0.0000000454	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg21550580	chr3:65755382	3	65755382	MAGI1	Open sea	0.0001467	2.68e-05	0.0000000457	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg23279503	chr8:35649016	8	35649016	UNC5D	Open sea	0.0001474	2.7e-05	0.0000000485	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg20525527	chr17:17056629	17	17056629	MPRIP	Open sea	-0.0001162	2.13e-05	0.0000000497	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg03308494	chr12:58013267	12	58013267	SLC26A10	Island	0.0001133	2.08e-05	0.0000000499	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg23279503	chr8:35649016	8	35649016	UNC5D	Open sea	0.0001881	3.45e-05	0.0000000515	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg12810800	chr2:159788345	2	159788345	-	Open sea	0.000172	3.16e-05	0.0000000522	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg05337441	chr2:21266568	2	21266568	APOB	North shore	0.000185	3.4e-05	0.0000000526	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg10001987	chr17:7381769	17	7381769	ZBTB4	North shore	-0.0002317	4.26e-05	0.0000000535	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg10001987	chr17:7381769	17	7381769	ZBTB4	North shore	-0.0002312	4.27e-05	0.0000000615	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg26874872	chr16:26156362	16	26156362	-	Open sea	0.0001687	3.12e-05	0.0000000628	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg05897122	chr4:53112707	4	53112707	-	Open sea	0.0001689	3.13e-05	0.0000000679	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg05337441	chr2:21266568	2	21266568	APOB	North shore	0.0002828	5.25e-05	0.0000000697	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg06785060	chr1:42180981	1	42180981	HIVEP3	Open sea	-6.58e-05	1.22e-05	0.0000000735	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg25073563	chr2:40514511	2	40514511	SLC8A1	Open sea	0.00015	2.79e-05	0.0000000752	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg10508349	chr16:68942231	16	68942231	TMCO7	Open sea	-6.47e-05	1.2e-05	0.0000000758	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg24378227	chr6:1396771	6	1396771	-	South shelf	0.0001212	2.26e-05	0.0000000776	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg02115781	chr2:172175273	2	172175273	METTL8	Open sea	0.000131	2.44e-05	0.000000078	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg10587082	chr1:208293478	1	208293478	PLXNA2	Open sea	0.0001371	2.56e-05	0.0000000815	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg06785060	chr1:42180981	1	42180981	HIVEP3	Open sea	-6.54e-05	1.22e-05	0.0000000816	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg13359998	chr1:230241764	1	230241764	GALNT2	Open sea	0.0001144	2.14e-05	0.0000000851	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg05337441	chr2:21266568	2	21266568	APOB	North shore	0.000181	3.37e-05	0.0000000866	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg14643264	chr9:27408242	9	27408242	MOBKL2B	Open sea	0.0001292	2.42e-05	0.0000000886	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg19654437	chr2:202671158	2	202671158	CDK15	Open sea	0.0001146	2.15e-05	0.0000000919	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg11001536	chr5:153489773	5	153489773	-	Open sea	0.0001743	3.26e-05	0.0000000922	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg18858517	chr20:57979326	20	57979326	-	South shore	-0.0001731	3.24e-05	0.0000000948	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg20525527	chr17:17056629	17	17056629	MPRIP	Open sea	-0.000114	2.14e-05	0.0000000965	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg03308494	chr12:58013267	12	58013267	SLC26A10	Island	0.0001112	2.08e-05	0.0000000972	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2304	2	68	Both	None	cg10508349	chr16:68942231	16	68942231	TMCO7	Open sea	-6.38e-05	1.2e-05	0.000000104	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg06621027	chr2:80179759	2	80179759	CTNNA2	Open sea	0.0001188	2.25e-05	0.000000124	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg10001987	chr17:7381769	17	7381769	ZBTB4	North shore	-0.0001701	3.25e-05	0.000000164	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg16736826	chr1:41951512	1	41951512	EDN2	Open sea	7.07e-05	1.35e-05	0.000000176	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg10001987	chr17:7381769	17	7381769	ZBTB4	North shore	-0.000167	3.23e-05	0.000000224	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg15705971	chr11:92110262	11	92110262	FAT3	Open sea	0.0001009	1.96e-05	0.000000246	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg11001536	chr5:153489773	5	153489773	-	Open sea	0.00013	2.53e-05	0.000000311	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg00753676	chr4:38662991	4	38662991	FLJ13197	North shore	-3.768	0.738	0.00000034	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg06785060	chr1:42180981	1	42180981	HIVEP3	Open sea	-4.96e-05	9.8e-06	0.000000417	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg23759710	chr2:42990957	2	42990957	OXER1	Open sea	-6.78e-05	1.34e-05	0.000000461	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg05609864	chr16:24550579	16	24550579	RBBP6	North shore	9.204	1.836	0.00000054	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg06621027	chr2:80179759	2	80179759	CTNNA2	Open sea	0.000112	2.24e-05	0.000000556	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg23759710	chr2:42990957	2	42990957	OXER1	Open sea	-6.63e-05	1.33e-05	0.000000657	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg06785060	chr1:42180981	1	42180981	HIVEP3	Open sea	-4.84e-05	9.8e-06	0.000000716	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg14643264	chr9:27408242	9	27408242	MOBKL2B	Open sea	9.94e-05	2.02e-05	0.000000818	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg25073563	chr2:40514511	2	40514511	SLC8A1	Open sea	0.000104	2.12e-05	0.000000882	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg04413986	chr12:57119373	12	57119373	NACA	Island	7.59	1.557	0.0000011	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg11001536	chr5:153489773	5	153489773	-	Open sea	0.0001231	2.54e-05	0.00000132	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg15705971	chr11:92110262	11	92110262	FAT3	Open sea	9.37e-05	1.95e-05	0.00000147	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg05897122	chr4:53112707	4	53112707	-	Open sea	0.0001076	2.24e-05	0.00000156	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg06747543	chr19:18589894	19	18589894	ELL	Open sea	10.415	2.172	0.0000016	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg24252746	chr15:45248932	15	45248932	C15orf43	Open sea	-7.116	1.496	0.000002	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg26105227	chr11:17495097	11	17495097	ABCC8	North shelf	0.000101	2.16e-05	0.00000278	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg20448706	chr14:32941841	14	32941841	AKAP6	Open sea	9.62e-05	2.05e-05	0.00000285	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg20448706	chr14:32941841	14	32941841	AKAP6	Open sea	9.49e-05	2.04e-05	0.00000323	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg03308494	chr12:58013267	12	58013267	SLC26A10	Island	7.35e-05	1.6e-05	0.00000442	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg00753676	chr4:38662991	4	38662991	FLJ13197	North shore	-8.595	1.874	0.0000045	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg03308494	chr12:58013267	12	58013267	SLC26A10	Island	7.37e-05	1.61e-05	0.0000047	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg15619673	chr7:16625816	7	16625816	-	North shore	-6.597	1.448	0.0000052	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg15899743	chr14:22985112	14	22985112	-	Open sea	11.276	2.477	0.0000053	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg18858517	chr20:57979326	20	57979326	-	South shore	-9.28e-05	2.04e-05	0.00000549	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg10587082	chr1:208293478	1	208293478	PLXNA2	Open sea	8.82e-05	1.94e-05	0.00000568	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg07962812	chr1:183441443	1	183441443	SMG7	Island	6.479	1.428	0.0000057	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg26105227	chr11:17495097	11	17495097	ABCC8	North shelf	9.87e-05	2.18e-05	0.0000057	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg26345203	chr14:23005866	14	23005866	-	Open sea	10.482	2.322	0.0000064	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg05897122	chr4:53112707	4	53112707	-	Open sea	1e-04	2.23e-05	0.00000684	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg15123809	chr10:105254427	10	105254427	NEURL	Island	-6.378	1.434	0.0000087	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg10289790	chr14:105359915	14	105359915	KIAA0284	Island	-8.492	1.918	0.0000095	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery adjusted for surrogate variables	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	645	1	63.2	Both	None	cg22322184	chr19:7734203	19	7734203	RETN	North shore	-10.384	2.345	0.0000095	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_adjusted_for_surrogate_variables
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1579	2	57	Both	None	cg00285394	chr8:126011954	8	126011954	SQLE	South shore	0.0002001	4.54e-05	0.0000104	-	28213390_serum_lowdensity_lipoprotein_cholesterol_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg10508349	chr16:68942231	16	68942231	TMCO7	Open sea	-4.23e-05	9.6e-06	0.000011	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg10508349	chr16:68942231	16	68942231	TMCO7	Open sea	-4.25e-05	9.7e-06	0.0000112	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg13359998	chr1:230241764	1	230241764	GALNT2	Open sea	7.91e-05	1.8e-05	0.0000114	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg25436634	chr3:181045270	3	181045270	-	Open sea	0.00014	3.2e-05	0.0000125	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg25436634	chr3:181045270	3	181045270	-	Open sea	0.0001396	3.22e-05	0.0000146	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg03188976	chr7:134443864	7	134443864	-	Open sea	8.33e-05	1.92e-05	0.0000148	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg12810800	chr2:159788345	2	159788345	-	Open sea	9.89e-05	2.29e-05	0.0000152	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg19654437	chr2:202671158	2	202671158	CDK15	Open sea	7.08e-05	1.64e-05	0.0000161	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1579	2	57	Both	None	cg00285394	chr8:126011954	8	126011954	SQLE	South shore	0.0001965	4.59e-05	0.0000182	-	28213390_serum_lowdensity_lipoprotein_cholesterol_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg08261450	chr12:130384734	12	130384734	TMEM132D	North shelf	8.82e-05	2.1e-05	0.0000274	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg03188976	chr7:134443864	7	134443864	-	Open sea	8.01e-05	1.91e-05	0.0000275	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S1	Serum low-density lipoprotein cholesterol	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	-	3187	2	65.7	Both	None	cg00753676	chr4:38662991	4	38662991	FLJ13197	North shore	-2.484	0.593	0.000028	-	28173150_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg12810800	chr2:159788345	2	159788345	-	Open sea	9.45e-05	2.27e-05	0.000032	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg26874872	chr16:26156362	16	26156362	-	Open sea	9.56e-05	2.33e-05	0.0000413	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg02115781	chr2:172175273	2	172175273	METTL8	Open sea	8.29e-05	2.05e-05	0.0000531	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication	Table S3	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	63	Both	None	cg08261450	chr12:130384734	12	130384734	TMEM132D	North shelf	8.32e-05	2.1e-05	0.0000728	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum low-density lipoprotein cholesterol	EFO_0004195, EFO_0004611	Discovery and replication adjusted for BMI	Table S7	DNA methylation	Serum low-density lipoprotein cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	3883	4	65	Both	None	cg21550580	chr3:65755382	3	65755382	MAGI1	Open sea	7.95e-05	2.02e-05	0.0000817	-	28213390_serum_lowdensity_lipoprotein_cholesterol_discovery_and_replication_adjusted_for_bmi