author consortium pmid date trait efo analysis source outcome exposure covariates outcome_units exposure_units methylation_array tissue further_details n n_cohorts age sex ethnicity cpg chrpos chr pos gene type beta se p details study_id Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 1776 1 61 Both European cg06500161 chr21:43656587 21 43656587 ABCG1 South shore 0.07 0.006 1.21e-27 - 25583993_triglycerides_discovery Irvin MR - 24920721 2014-08-12 Triglycerides EFO_0004530 Discovery Table 1 DNA methylation Triglycerides Age, sex and technical covariates Beta values mg/dl Illumina HumanMethylation450 CD4+ T-cells Triglycerides levels were log-transformed 991 1 49 Both European cg00574958 chr11:68607622 11 68607622 CPT1A North shore -0.032 0.00299 1.5600000000000002e-26 - 24920721_triglycerides Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for lipid-lowering medication use Table 3 DNA methylation Triglycerides Age, sex, smoking, lipid-lowering medication use, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg00574958 chr11:68607622 11 68607622 CPT1A North shore -0.0142 0.0013 2.6e-26 - 28194238_triglycerides_discovery_and_replication_lipidlowering_medication_use_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg00574958 chr11:68607622 11 68607622 CPT1A North shore -0.0139 0.0013 5.07e-26 - 28194238_triglycerides_discovery_and_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg06500161 chr21:43656587 21 43656587 ABCG1 South shore 0.0173 0.0017 1.4199999999999999e-25 - 28194238_triglycerides_discovery_and_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for lipid-lowering medication use Table 3 DNA methylation Triglycerides Age, sex, smoking, lipid-lowering medication use, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg06500161 chr21:43656587 21 43656587 ABCG1 South shore 0.0167 0.0016 1.3999999999999999e-24 - 28194238_triglycerides_discovery_and_replication_lipidlowering_medication_use_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for other lipids Table 3 DNA methylation Triglycerides Age, sex, smoking, other lipids, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg00574958 chr11:68607622 11 68607622 CPT1A North shore -0.0161 0.0016 1.5000000000000002e-22 - 28194238_triglycerides_discovery_and_replication_other_lipids_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg11024682 chr17:17730094 17 17730094 SREBF1 South shelf 0.015 0.0016 2.85e-20 - 28194238_triglycerides_discovery_and_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for lipid-lowering medication use Table 3 DNA methylation Triglycerides Age, sex, smoking, lipid-lowering medication use, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg11024682 chr17:17730094 17 17730094 SREBF1 South shelf 0.0147 0.0016 3e-19 - 28194238_triglycerides_discovery_and_replication_lipidlowering_medication_use_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for waist circumference Table 3 DNA methylation Triglycerides Age, sex, smoking, waist circumference, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg06500161 chr21:43656587 21 43656587 ABCG1 South shore 0.0153 0.0018 3.9e-18 - 28194238_triglycerides_discovery_and_replication_waist_circumference_adjusted Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 1776 1 61 Both European cg19693031 chr1:145441552 1 145441552 TXNIP Open sea -0.03 0.003 1.89e-17 - 25583993_triglycerides_discovery Irvin MR - 24920721 2014-08-12 Triglycerides EFO_0004530 Discovery Table 1 DNA methylation Triglycerides Age, sex and technical covariates Beta values mg/dl Illumina HumanMethylation450 CD4+ T-cells Triglycerides levels were log-transformed 991 1 49 Both European cg17058475 chr11:68607737 11 68607737 CPT1A North shore -0.035 0.00414 8.9e-17 - 24920721_triglycerides Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for waist circumference Table 3 DNA methylation Triglycerides Age, sex, smoking, waist circumference, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg00574958 chr11:68607622 11 68607622 CPT1A North shore -0.0114 0.0014 1.9e-16 - 28194238_triglycerides_discovery_and_replication_waist_circumference_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for other lipids Table 3 DNA methylation Triglycerides Age, sex, smoking, other lipids, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg17058475 chr11:68607737 11 68607737 CPT1A North shore -0.0196 0.0024 9.2e-16 - 28194238_triglycerides_discovery_and_replication_other_lipids_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 725 1 60 Both None cg00574958 chr11:68607622 11 68607622 CPT1A North shore -0.0206 0.0026 0.00000000000000123 - 28194238_triglycerides_discovery Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Replication Table 2 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 760 1 68 Both None cg06500161 chr21:43656587 21 43656587 ABCG1 South shore 0.0201 0.0025 0.00000000000000146 - 28194238_triglycerides_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg27243685 chr21:43642366 21 43642366 ABCG1 South shelf 0.0085 0.0011 0.0000000000000099 - 28194238_triglycerides_discovery_and_replication Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 1776 1 61 Both European cg11024682 chr17:17730094 17 17730094 SREBF1 South shelf 0.059 0.008 0.0000000000000554 - 25583993_triglycerides_discovery Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for other lipids Table 3 DNA methylation Triglycerides Age, sex, smoking, other lipids, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg06500161 chr21:43656587 21 43656587 ABCG1 South shore 0.0151 0.002 0.00000000000007 - 28194238_triglycerides_discovery_and_replication_other_lipids_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for lipid-lowering medication use Table 3 DNA methylation Triglycerides Age, sex, smoking, lipid-lowering medication use, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg17058475 chr11:68607737 11 68607737 CPT1A North shore -0.0146 0.002 0.00000000000031 - 28194238_triglycerides_discovery_and_replication_lipidlowering_medication_use_adjusted Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 1776 1 61 Both European cg00574958 chr11:68607622 11 68607622 CPT1A North shore -0.118 0.016 0.000000000000315 - 25583993_triglycerides_discovery Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 1776 1 61 Both European cg27243685 chr21:43642366 21 43642366 ABCG1 South shelf 0.064 0.009 0.000000000000324 - 25583993_triglycerides_discovery Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Replication Table 2 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 760 1 68 Both None cg00574958 chr11:68607622 11 68607622 CPT1A North shore -0.0114 0.0016 0.000000000000724 - 28194238_triglycerides_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for waist circumference Table 3 DNA methylation Triglycerides Age, sex, smoking, waist circumference, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg11024682 chr17:17730094 17 17730094 SREBF1 South shelf 0.0124 0.0017 0.00000000000084 - 28194238_triglycerides_discovery_and_replication_waist_circumference_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg17058475 chr11:68607737 11 68607737 CPT1A North shore -0.014 0.002 0.00000000000153 - 28194238_triglycerides_discovery_and_replication Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 1776 1 61 Both European cg07504977 chr10:102131012 10 102131012 - North shelf 0.026 0.004 0.00000000000393 - 25583993_triglycerides_discovery Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for other lipids Table 3 DNA methylation Triglycerides Age, sex, smoking, other lipids, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg11024682 chr17:17730094 17 17730094 SREBF1 South shelf 0.0138 0.002 0.00000000001 - 28194238_triglycerides_discovery_and_replication_other_lipids_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Replication Table 2 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 760 1 68 Both None cg11024682 chr17:17730094 17 17730094 SREBF1 South shelf 0.0172 0.0026 0.0000000000327 - 28194238_triglycerides_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 725 1 60 Both None cg06500161 chr21:43656587 21 43656587 ABCG1 South shore 0.0149 0.0023 0.0000000000502 - 28194238_triglycerides_discovery Irvin MR - 24920721 2014-08-12 Triglycerides EFO_0004530 Discovery Table 1 DNA methylation Triglycerides Age, sex and technical covariates Beta values mg/dl Illumina HumanMethylation450 CD4+ T-cells Triglycerides levels were log-transformed 991 1 49 Both European cg01082498 chr11:68608225 11 68608225 CPT1A Island -0.011 0.00163 0.0000000000879 - 24920721_triglycerides Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 725 1 60 Both None cg11024682 chr17:17730094 17 17730094 SREBF1 South shelf 0.0135 0.0021 0.00000000034 - 28194238_triglycerides_discovery Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Replication Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 971 2 62 Both European cg06500161 chr21:43656587 21 43656587 ABCG1 South shore - - 0.000000000556 - 25583993_triglycerides_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg24174557 chr17:57903544 17 57903544 TMEM49 Open sea -0.0145 0.0024 0.0000000007 - 28194238_triglycerides_discovery_and_replication Irvin MR - 24920721 2014-08-12 Triglycerides EFO_0004530 Discovery Table 1 DNA methylation Triglycerides Age, sex and technical covariates Beta values mg/dl Illumina HumanMethylation450 CD4+ T-cells Triglycerides levels were log-transformed 991 1 49 Both European cg09737197 chr11:68607675 11 68607675 CPT1A North shore -0.027 0.00436 0.00000000153 - 24920721_triglycerides Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 1776 1 61 Both European cg20544516 chr17:17717183 17 17717183 MIR33B;SREBF1 South shore 0.043 0.007 0.00000000284 - 25583993_triglycerides_discovery Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg06500161 chr21:43656587 21 43656587 ABCG1 South shore 0.5 0.083 0.0000000043 None Battram-T_triglycerides_fasting Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 1776 1 61 Both European cg12556569 chr11:116664039 11 116664039 APOA5 South shelf 0.005 0.001 0.00000000643 - 25583993_triglycerides_discovery Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for waist circumference Table 3 DNA methylation Triglycerides Age, sex, smoking, waist circumference, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg17058475 chr11:68607737 11 68607737 CPT1A North shore -0.012 0.0021 0.0000000088 - 28194238_triglycerides_discovery_and_replication_waist_circumference_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg01176028 chr21:43653234 21 43653234 ABCG1 North shore 0.0123 0.0022 0.0000000122 - 28194238_triglycerides_discovery_and_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg13925011 chr1:111216387 1 111216387 KCNA3 Island -0.0097 0.0017 0.0000000126 - 28194238_triglycerides_discovery_and_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg17901584 chr1:55353706 1 55353706 DHCR24 South shore -0.0131 0.0023 0.0000000152 - 28194238_triglycerides_discovery_and_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 725 1 60 Both None cg17901584 chr1:55353706 1 55353706 DHCR24 South shore -0.0162 0.0029 0.0000000156 - 28194238_triglycerides_discovery Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for lipid-lowering medication use Table 3 DNA methylation Triglycerides Age, sex, smoking, lipid-lowering medication use, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg17901584 chr1:55353706 1 55353706 DHCR24 South shore -0.013 0.0023 0.000000019 - 28194238_triglycerides_discovery_and_replication_lipidlowering_medication_use_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg06690548 chr4:139162808 4 139162808 SLC7A11 Open sea -0.0089 0.0016 0.0000000391 - 28194238_triglycerides_discovery_and_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg06734985 chr11:26849501 11 26849501 - Open sea -0.0129 0.0024 0.0000000519 - 28194238_triglycerides_discovery_and_replication Ouidir M Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies Singleton cohort 32677467 07-17-2020 triglycerides CHEBI_17855 binary definition where high is more than 150 mg/dl Table 2 DNA methylation triglycerides Age, Batch effects, Ancestry (genomic PCs), fetal sex, Cell composition (reference free) M values None Illumina HumanMethylation450 placenta The authors also compared their EWAS results to results from previous EWAS of the same traits (look up of 434 CpGs). These were unaccessible to us in the supplementary material. 262 1 Adults Females Other cg07255925 chr10:93073139 10 93073139 LOC100188947 Open sea -0.011 0.002 0.000000067 bacon corrected P. SE calculated 32677467_Ouidir-M_triglycerides_binary_definition_where_high_is_more_than_150_mg_dl Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication Table S1 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg19693031 chr1:145441552 1 145441552 TXNIP Open sea -0.0133 0.0025 0.0000000672 - 28194238_triglycerides_discovery_and_replication Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 1776 1 61 Both European cg07397296 chr21:43655316 21 43655316 ABCG1 Island 0.027 0.005 0.0000000948 - 25583993_triglycerides_discovery Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 1776 1 61 Both European cg07815238 chr15:64341005 15 64341005 - South shelf 0.048 0.009 0.0000000966 - 25583993_triglycerides_discovery Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery Table 2 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 725 1 60 Both None cg17058475 chr11:68607737 11 68607737 CPT1A North shore -0.0183 0.0034 0.0000000984 - 28194238_triglycerides_discovery Ouidir M Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies Singleton cohort 32677467 07-17-2020 triglycerides CHEBI_17855 binary definition where high is more than 150 mg/dl Table 2 DNA methylation triglycerides Age, Batch effects, Ancestry (genomic PCs), fetal sex, Cell composition (reference free) M values None Illumina HumanMethylation450 placenta The authors also compared their EWAS results to results from previous EWAS of the same traits (look up of 434 CpGs). These were unaccessible to us in the supplementary material. 262 1 Adults Females Other cg09326404 chr1:46956839 1 46956839 - Island 0.049 0.0091 0.00000017 bacon corrected P. SE calculated 32677467_Ouidir-M_triglycerides_binary_definition_where_high_is_more_than_150_mg_dl Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg06690548 chr4:139162808 4 139162808 SLC7A11 Open sea -0.43 0.082 0.00000023 None Battram-T_triglycerides_fasting Ouidir M Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies Singleton cohort 32677467 07-17-2020 triglycerides CHEBI_17855 binary definition where high is more than 150 mg/dl Table 2 DNA methylation triglycerides Age, Batch effects, Ancestry (genomic PCs), fetal sex, Cell composition (reference free) M values None Illumina HumanMethylation450 placenta The authors also compared their EWAS results to results from previous EWAS of the same traits (look up of 434 CpGs). These were unaccessible to us in the supplementary material. 262 1 Adults Females Other cg02785814 chr11:44338707 11 44338707 - Island -0.019 0.0036 0.00000033 bacon corrected P. SE calculated 32677467_Ouidir-M_triglycerides_binary_definition_where_high_is_more_than_150_mg_dl Ouidir M Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies Singleton cohort 32677467 07-17-2020 triglycerides CHEBI_17855 binary definition where high is more than 150 mg/dl Table 2 DNA methylation triglycerides Age, Batch effects, Ancestry (genomic PCs), fetal sex, Cell composition (reference free) M values None Illumina HumanMethylation450 placenta The authors also compared their EWAS results to results from previous EWAS of the same traits (look up of 434 CpGs). These were unaccessible to us in the supplementary material. 262 1 Adults Females Other cg04985482 chr6:31382065 6 31382065 MICA Open sea -0.035 0.0067 0.00000038 bacon corrected P. SE calculated 32677467_Ouidir-M_triglycerides_binary_definition_where_high_is_more_than_150_mg_dl Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg19222480 chr20:44441446 20 44441446 UBE2C Island 0.0165 0.003 0.00000065 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg16149053 chr10:15413461 10 15413461 FAM171A1 South shore 0.0213 0.004 0.00000087 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg26945643 chr7:2695248 7 2695248 TTYH3 North shelf -0.0483 0.0092 0.0000013 None 31910897_Cronjé-HT_triglycerides Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Replication Table 2 DNA methylation Triglycerides Age, sex, smoking, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 760 1 68 Both None cg17058475 chr11:68607737 11 68607737 CPT1A North shore -0.0118 0.0025 0.00000171 - 28194238_triglycerides_replication Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg05306860 chr17:18150799 17 18150799 FLII Island 0.136 0.0263 0.0000019 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg12985237 chr5:6739530 5 6739530 POLS South shore -0.0367 0.0072 0.0000023 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg15111469 chr5:121415023 5 121415023 LOX South shore -0.41 0.087 0.0000025 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg23507945 chr6:137477184 6 137477184 IL22RA2 Open sea -0.0059 0.0012 0.0000031 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg12913587 chr5:1232923 5 1232923 SLC6A18 South shore 0.057 0.0113 0.0000032 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg17772490 chr12:57119086 12 57119086 NACA Island 0.29 0.061 0.0000034 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg13167102 chr22:18365681 22 18365681 MICAL3 Open sea 0.0212 0.0042 0.0000034 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg14476101 chr1:120255992 1 120255992 PHGDH South shore -0.37 0.08 0.0000037 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg15031127 chr16:21133049 16 21133049 DNAH3 Open sea -0.0332 0.0067 0.0000041 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg01824466 chr8:95959531 8 95959531 TP53INP1 North shore -0.29 0.062 0.0000045 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg00925778 chr10:105113085 10 105113085 - South shelf -0.0389 0.0079 0.0000047 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg00454346 chr1:89820011 1 89820011 - Open sea -0.0401 0.0081 0.000005 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg13673837 chr19:15306670 19 15306670 NOTCH3 Island 0.32 0.071 0.0000052 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg16806794 chr7:152591581 7 152591581 - Island 0.0147 0.003 0.0000054 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg26719542 chr16:50873851 16 50873851 - North shore 0.37 0.082 0.0000056 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg13114777 chr2:228753156 2 228753156 DAW1 Open sea -0.0887 0.0182 0.000006 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg11582226 chr13:77587296 13 77587296 FBXL3 Open sea -0.0286 0.0059 0.0000072 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg09529165 chr17:45808345 17 45808345 - North shelf 0.32 0.071 0.0000078 None Battram-T_triglycerides_fasting Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Replication Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 971 2 62 Both European cg00574958 chr11:68607622 11 68607622 CPT1A North shore - - 0.00000788 - 25583993_triglycerides_replication Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg24891034 chr6:33422244 6 33422244 ZBTB9 Island -0.12 0.028 0.0000082 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg16364344 chr8:36641508 8 36641508 KCNU1 Open sea -0.0419 0.0088 0.0000092 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg11421702 chr13:73301012 13 73301012 C13orf37;C13orf34 North shore 0.0294 0.0062 0.00001 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg02378663 chr14:24841791 14 24841791 NFATC4 South shelf -0.0381 0.0081 0.000011 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg07781645 chr8:16059680 8 16059680 - Open sea -0.0336 0.0073 0.000015 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg10180141 chr1:14041267 1 14041267 PRDM2 Open sea -0.0585 0.0126 0.000015 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg13540860 chr10:438517 10 438517 DIP2C Open sea -0.0849 0.0184 0.000016 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg14762845 chr17:3500390 17 3500390 TRPV1 Open sea -0.0332 0.0072 0.000016 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg27146152 chr17:6659364 17 6659364 XAF1 Open sea 0.28 0.064 0.000016 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg24733553 chr3:100384124 3 100384124 ADGRG7 Open sea -0.0499 0.0108 0.000016 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg04117480 chr1:120439522 1 120439522 ADAM30 South shore 0.27 0.062 0.000017 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg27298324 chr1:182587340 1 182587340 - South shelf 0.36 0.083 0.000017 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg12198913 chr11:44972718 11 44972718 TP53I11 South shore 0.0314 0.0069 0.000019 None 31910897_Cronjé-HT_triglycerides Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Replication Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 971 2 62 Both European cg07504977 chr10:102131012 10 102131012 - North shelf - - 0.0000191 - 25583993_triglycerides_replication Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg23412797 chr17:79257094 17 79257094 SLC38A10 South shore -0.0577 0.0127 0.00002 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg20750642 chr13:99100586 13 99100586 FARP1 Open sea 0.0735 0.0162 0.000021 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg27295621 chr2:44880258 2 44880258 CAMKMT Open sea 0.0308 0.0068 0.000021 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg07589884 chr6:92103181 6 92103181 - Open sea -0.0413 0.0091 0.000021 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg12538313 chr15:56330450 15 56330450 - Open sea -0.0138 0.003 0.000021 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg22862005 chr1:205884321 1 205884321 SLC26A9 Open sea 0.2 0.047 0.000022 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg03454364 chrX:147133830 X 147133830 - Island -0.0481 0.0106 0.000023 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg07039975 chr2:74592036 2 74592036 DCTN1 Open sea -0.31 0.073 0.000023 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg06240704 chr2:201775847 2 201775847 ORC2L Open sea 0.28 0.067 0.000024 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg12391858 chr15:43441510 15 43441510 TMEM62 Open sea 0.2 0.047 0.000024 None Battram-T_triglycerides_fasting Pfeiffer L - 25583993 2015-01-12 Triglycerides EFO_0004530, CHEBI_17855 Replication Table 2 Triglycerides DNA methylation Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts mg/dl Beta values Illumina HumanMethylation450 Whole blood - 971 2 62 Both European cg27243685 chr21:43642366 21 43642366 ABCG1 South shelf - - 0.0000249 - 25583993_triglycerides_replication Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for other lipids Table 3 DNA methylation Triglycerides Age, sex, smoking, other lipids, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg17901584 chr1:55353706 1 55353706 DHCR24 South shore -0.012 0.0028 0.000025 - 28194238_triglycerides_discovery_and_replication_other_lipids_adjusted Braun KVE - 28194238 2016-06-16 Triglycerides EFO_0004530, CHEBI_17855 Discovery and replication adjusted for waist circumference Table 3 DNA methylation Triglycerides Age, sex, smoking, waist circumference, cell counts and technical covariates Beta values mmol/l Illumina HumanMethylation450 Whole blood - 1485 2 64 Both None cg17901584 chr1:55353706 1 55353706 DHCR24 South shore -0.0104 0.0025 0.000025 - 28194238_triglycerides_discovery_and_replication_waist_circumference_adjusted Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg24147849 chr3:100053372 3 100053372 NIT2 North shore 0.0057 0.0013 0.000025 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg09823077 chr16:89452360 16 89452360 ANKRD11 North shelf 0.33 0.079 0.000025 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg22861256 chr11:57667881 11 57667881 - Open sea -0.0623 0.0139 0.000026 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg07927120 chr16:12353600 16 12353600 SNX29 North shore -0.0257 0.0057 0.000027 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg06856378 chr2:160759118 2 160759118 LY75 North shore -0.0397 0.0089 0.000028 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg10269431 chr4:110837358 4 110837358 EGF Open sea 0.33 0.078 0.000029 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg27231166 chr13:42163992 13 42163992 KIAA0564 Open sea -0.0334 0.0075 0.000029 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg20263853 chr1:8824177 1 8824177 RERE Open sea -0.044 0.0099 0.00003 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg08822360 chr10:94459553 10 94459553 - Island 0.0116 0.0026 0.00003 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg14661225 chr19:46171451 19 46171451 GIPR North shelf 0.0174 0.0039 0.00003 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg10706073 chr17:46328419 17 46328419 SKAP1 Open sea 0.26 0.061 0.000031 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg09685420 chr14:93235246 14 93235246 - Open sea 0.0099 0.0022 0.000031 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg08201760 chr4:113172257 4 113172257 AP1AR Open sea 0.0357 0.0081 0.000031 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg11656262 chr1:15912795 1 15912795 AGMAT South shore 0.3 0.071 0.000032 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg03716936 chr10:124908747 10 124908747 HMX2 Island 0.0865 0.0196 0.000033 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg13577145 chr16:56865768 16 56865768 NUP93 Open sea -0.025 0.0057 0.000035 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg12142501 chr8:1765358 8 1765358 MIR596 South shore -0.031 0.0071 0.000036 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg26760589 chr20:55839288 20 55839288 BMP7 Island -0.31 0.075 0.000037 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg04789905 chr1:150237906 1 150237906 APH1A North shelf -0.3 0.072 0.000038 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg08579753 chr1:39174525 1 39174525 - Island 0.15 0.036 0.000038 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg16371229 chr1:233248845 1 233248845 PCNXL2 Open sea 0.0156 0.0036 0.000038 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg00908733 chr19:51071294 19 51071294 LRRC4B South shore 0.27 0.065 0.000038 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg06814813 chr11:85905930 11 85905930 - Open sea -0.0328 0.0075 0.000038 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg19693031 chr1:145441552 1 145441552 TXNIP Open sea -0.0477 0.0109 0.000039 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg16984132 chr11:117052181 11 117052181 SIDT2 South shore 0.0303 0.0069 0.000039 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg27243685 chr21:43642366 21 43642366 ABCG1 South shelf 0.3 0.073 0.000039 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg07906004 chr6:157982346 6 157982346 ZDHHC14 Open sea -0.0239 0.0055 0.000039 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg04451404 chr4:27050033 4 27050033 - Open sea 0.0136 0.0031 0.000039 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg04532989 chr11:47193565 11 47193565 ARFGAP2 Open sea -0.179 0.0409 0.000039 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg21123434 chr5:179107964 5 179107964 CBY3 South shore -0.0154 0.0035 0.000042 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg14673387 chr10:47008185 10 47008185 - Island 0.27 0.065 0.000042 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg04152616 chr16:88479315 16 88479315 - Open sea 0.063 0.0145 0.000045 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg20054420 chr12:22590199 12 22590199 - Open sea 0.0317 0.0073 0.000046 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg11219917 chr4:819151 4 819151 CPLX1 Island 0.35 0.085 0.000047 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg22991936 chr14:105255472 14 105255472 AKT1 South shelf 0.35 0.085 0.000047 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg19405624 chr19:56671981 19 56671981 ZNF444 South shore -0.0951 0.022 0.000047 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg05827732 chr3:96533699 3 96533699 EPHA6 South shore 0.27 0.067 0.000048 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg01254260 chr6:142670499 6 142670499 ADGRG6 Open sea -0.0613 0.0142 0.000048 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg08603863 chr13:110667257 13 110667257 - Open sea -0.0184 0.0043 0.000049 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg16371688 chr1:183207463 1 183207463 LAMC2 Open sea -0.0409 0.0095 0.00005 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg04478205 chr13:32872091 13 32872091 - Open sea -0.0212 0.0049 0.00005 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg06533577 chr7:64760504 7 64760504 - Open sea 0.106 0.0246 0.00005 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg18767964 chr1:38529973 1 38529973 - Open sea -0.28 0.069 0.000051 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg08857994 chr2:130763641 2 130763641 - Island 0.0522 0.0122 0.000053 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg00484466 chr4:8071202 4 8071202 ABLIM2 Open sea -0.25 0.061 0.000053 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg18556540 chr6:30181032 6 30181032 TRIM26 Island 0.0107 0.0025 0.000053 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg06118999 chr10:90343192 10 90343192 RNLS Island -0.0203 0.0047 0.000053 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg04190262 chr16:69442518 16 69442518 - Open sea 0.0252 0.0059 0.000053 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg24878115 chr19:18545062 19 18545062 SSBP4 Island -0.24 0.059 0.000054 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg25351643 chr1:115681624 1 115681624 - Open sea 0.0431 0.0101 0.000055 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg21639713 chr3:147123123 3 147123123 ZIC4 North shelf 0.31 0.077 0.000056 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg01151720 chr14:23016209 14 23016209 - Open sea 0.0413 0.0097 0.000056 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg18028483 chr6:109307801 6 109307801 SESN1 Open sea 0.22 0.055 0.000057 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg08128925 chr19:11141458 19 11141458 SMARCA4 North shelf -0.0236 0.0055 0.000057 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg17545218 chr6:28831849 6 28831849 - Island -0.27 0.067 0.000058 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg26792161 chr10:127829597 10 127829597 ADAM12 Open sea -0.0151 0.0035 0.000058 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg16693818 chr17:32640541 17 32640541 - Open sea 0.0251 0.0059 0.00006 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg02357741 chr19:55813339 19 55813339 BRSK1 North shore 0.19 0.046 0.00006 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg06631028 chr4:77680657 4 77680657 SHROOM3 Open sea 0.0291 0.0069 0.00006 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg09759808 chr2:113012921 2 113012921 ZC3H8 South shore -0.0331 0.0078 0.000061 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg03208489 chr11:63647865 11 63647865 MARK2 Open sea -0.035 0.0082 0.000061 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg04991805 chr10:99790910 10 99790910 CRTAC1 Island -0.23 0.058 0.000062 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg23877401 chr12:122017247 12 122017247 KDM2B Island -0.28 0.07 0.000062 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg04244665 chr17:70622064 17 70622064 LINC00511 Open sea -0.0275 0.0065 0.000063 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg00324205 chr15:94911890 15 94911890 MCTP2 Open sea -0.16 0.041 0.000064 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg06638874 chr6:168684732 6 168684732 - Island -0.0428 0.0101 0.000065 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg21418052 chr13:31773806 13 31773806 B3GALTL North shore -0.3 0.075 0.000066 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg13654833 chr9:80062321 9 80062321 GNA14-AS1;GNA14 Open sea -0.0464 0.011 0.000068 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg05927274 chr1:153457181 1 153457181 - Open sea 0.21 0.053 0.000069 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg17478228 chr19:11591593 19 11591593 ELAVL3 Island 0.35 0.087 0.00007 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg09728487 chr4:141079462 4 141079462 - South shelf -0.0337 0.008 0.000071 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg19779965 chr5:45135681 5 45135681 - Open sea -0.23 0.057 0.000072 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg15312943 chr11:17843855 11 17843855 SERGEF Open sea 0.037 0.0088 0.000072 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg06451566 chr6:107187275 6 107187275 LOC100422737 Open sea -0.0185 0.0044 0.000072 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg21429551 chr7:30635762 7 30635762 GARS South shore -0.31 0.078 0.000073 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg05968233 chr19:6372277 19 6372277 ALKBH7 North shore -0.126 0.0301 0.000073 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg17002133 chr3:126374351 3 126374351 TXNRD3 South shore -0.0459 0.0109 0.000074 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg20864959 chr1:225841654 1 225841654 ENAH Island 0.0224 0.0053 0.000075 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg03315476 chr1:40915606 1 40915606 ZNF643 Island 0.0057 0.0014 0.000076 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg26098815 chr8:1270577 8 1270577 - Open sea -0.0747 0.0178 0.000076 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg21743924 chr3:170470815 3 170470815 - Open sea 0.0488 0.0116 0.000076 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg02915696 chr21:37807965 21 37807965 - Open sea -0.154 0.0368 0.000077 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg09880551 chr21:42218932 21 42218932 DSCAM Island -0.3 0.075 0.000078 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg16412019 chr19:37741611 19 37741611 LINC01535 North shore 0.0227 0.0054 0.000078 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg10476206 chr10:12543444 10 12543444 CAMK1D Open sea -0.0483 0.0116 0.000079 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg10855773 chr12:27973808 12 27973808 - Open sea -0.0378 0.0091 0.00008 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg01224922 chr12:2215043 12 2215043 CACNA1C Open sea -0.0492 0.0118 0.000082 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg27114120 chr20:5296302 20 5296302 PROKR2 Island -0.34 0.086 0.000083 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg05331498 chr3:53880775 3 53880775 CHDH;IL17RB Island 0.29 0.074 0.000084 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg18181571 chr5:52082858 5 52082858 ITGA1;PELO North shore -0.0347 0.0083 0.000084 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg14636942 chr4:55090812 4 55090812 - North shelf -0.0151 0.0036 0.000086 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg03450842 chr10:80834947 10 80834947 ZMIZ1 Open sea -0.3 0.075 0.000086 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg22397404 chr1:44090998 1 44090998 - Open sea -0.0207 0.005 0.000087 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg09778927 chr17:40288533 17 40288533 RAB5C Open sea -0.038 0.0092 0.000088 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg02332678 chr11:3170821 11 3170821 OSBPL5 Open sea -0.0444 0.0107 0.000089 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg20318662 chr2:47452 2 47452 FAM110C South shore 0.34 0.086 0.00009 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg16911002 chr13:41635077 13 41635077 WBP4 Island 0.0072 0.0017 0.000091 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg27181471 chr1:4794111 1 4794111 AJAP1 Open sea -0.0364 0.0088 0.000092 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg13836550 chr10:118084504 10 118084504 C10orf96 Open sea 0.34 0.087 0.000092 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg07994696 chr16:11680075 16 11680075 LITAF Island 0.0361 0.0087 0.000092 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg08155759 chr19:57324295 19 57324295 PEG3;ZIM2;PEG3AS Open sea 0.26 0.065 0.000094 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg11182893 chr13:114842103 13 114842103 RASA3 South shore 0.29 0.073 0.000095 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg22972976 chr15:71481747 15 71481747 THSD4-AS1;THSD4 Open sea 0.026 0.0063 0.000095 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg13285862 chr12:121735363 12 121735363 CAMKK2 South shore -0.24 0.06 0.000096 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg05765580 chr17:26120370 17 26120370 NOS2 Island 0.34 0.087 0.000097 None Battram-T_triglycerides_fasting Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg13699478 chr7:121650873 7 121650873 PTPRZ1 Open sea -0.0215 0.0052 0.000098 None 31910897_Cronjé-HT_triglycerides Cronjé HT Prospective Urban and Rural Epidemiology study 31910897 2020-01-07 Triglycerides EFO_0004530 None Additional file 2e DNA methylation Triglycerides Age, body mass index, cell composition (reference based), batch effects Beta Values log mg/dL Illumina HumanMethylationEPIC Whole blood None 117 1 Adults Males African cg05547888 chr19:58125531 19 58125531 ZNF134 Island 0.0068 0.0016 0.000099 None 31910897_Cronjé-HT_triglycerides Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg14555481 chr19:46406481 19 46406481 MYPOP Island 0.31 0.08 0.000099 None Battram-T_triglycerides_fasting Battram T ARIES None 2020-08-20 Triglycerides EFO_0004530 fasting None DNA methylation Triglycerides Batch effects, cell composition (reference free), ancestry (genomic PCs) Beta Values mmol/l Illumina HumanMethylation450 Whole blood None 678 1 Adults Females European cg22808633 chr19:15563870 19 15563870 RASAL3 Island 0.3 0.076 0.000099 None Battram-T_triglycerides_fasting