Search results for ORMDL3
| Author | PMID | Outcome | Exposure | Tissue | Analysis | N | CpG | Location | Gene | Beta | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg01482279 | chr17:38083788 | ORMDL3 | 0.0005 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg04308185 | chr17:38084377 | ORMDL3 | -0.0055 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg04308185 | chr17:38084377 | ORMDL3 | 0.017 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg08932654 | chr17:38084459 | ORMDL3 | -0.0047 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg08932654 | chr17:38084459 | ORMDL3 | 0.015 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg10444806 | chr17:38084428 | ORMDL3 | -0.0036 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg10444806 | chr17:38084428 | ORMDL3 | 0.013 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg12655416 | chr17:38077870 | ORMDL3 | 0.0036 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg16638648 | chr17:38083781 | ORMDL3 | -7.8e-05 | 0E+00 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3755903 (gene symbol: GSDMB) | Whole blood | Meta-analysis | 4170 | cg22144450 | chr17:38080378 | ORMDL3 | NA | 4.2E-154 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg04308185 | chr17:38084377 | ORMDL3 | 0.48 | 6.2E-135 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg08932654 | chr17:38084459 | ORMDL3 | 0.33 | 1.3E-123 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg12655416 | chr17:38077870 | ORMDL3 | 0.24 | 8.9E-119 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg10444806 | chr17:38084428 | ORMDL3 | 0.32 | 1E-117 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg19511844 | chr17:38084119 | ORMDL3 | 0.12 | 3.5E-88 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3755934 (gene symbol: ORMDL3) | Whole blood | Meta-analysis | 4170 | cg18711369 | chr17:38081186 | ORMDL3 | NA | 5.6E-87 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg04308185 | chr17:38084377 | ORMDL3 | NA | 2.2E-82 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3755903 (gene symbol: GSDMB) | Whole blood | Meta-analysis | 4170 | cg18711369 | chr17:38081186 | ORMDL3 | NA | 2.7E-81 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg08932654 | chr17:38084459 | ORMDL3 | NA | 2.1E-79 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg18711369 | chr17:38081186 | ORMDL3 | 0.26 | 5.7E-75 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.146165 | 7.3E-71 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3755903 (gene symbol: GSDMB) | Whole blood | Meta-analysis | 4170 | cg10909506 | chr17:38081995 | ORMDL3 | NA | 4E-68 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg10909506 | chr17:38081995 | ORMDL3 | -0.25478 | 7.6E-67 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.130165 | 1.9E-56 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.126869 | 1.1E-53 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3755903 (gene symbol: GSDMB) | Whole blood | Meta-analysis | 4170 | cg12655416 | chr17:38077870 | ORMDL3 | NA | 8E-53 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.123191 | 1E-50 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.121211 | 3.9E-49 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg12655416 | chr17:38077870 | ORMDL3 | 2.0 | 1.7E-47 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.116551 | 1.5E-45 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg10444806 | chr17:38084428 | ORMDL3 | NA | 1.2E-44 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg22144450 | chr17:38080378 | ORMDL3 | 1.6 | 5.3E-40 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg18711369 | chr17:38081186 | ORMDL3 | 2.5 | 1.7E-39 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg04308185 | chr17:38084377 | ORMDL3 | 2.1 | 2.5E-32 |
| Wozniak MB | 23526956 | DNA methylation | Clear cell renal carcinoma | Clear cell renal carcinoma tumour cells and adjacent healthy cells | - | 129 | cg18711369 | chr17:38081186 | ORMDL3 | NA | 3.2E-32 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0898609 | 1.1E-27 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg12655416 | chr17:38077870 | ORMDL3 | NA | 1.1E-25 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg26971420 | chr17:38085230 | ORMDL3 | 0.023 | 5.7E-25 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0822371 | 1.9E-23 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.077 | 8.6E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.076 | 2.9E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0750238 | 9.1E-20 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3755903 (gene symbol: GSDMB) | Whole blood | Meta-analysis | 4170 | cg19511844 | chr17:38084119 | ORMDL3 | NA | 5.7E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0730164 | 8.4E-19 |
| Nones K | 24500968 | DNA methylation | Pancreatic ductal adenocarcinoma | Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata | - | 196 | cg26971420 | chr17:38085230 | ORMDL3 | NA | 9E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0724467 | 1.6E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.072 | 2.9E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.071 | 5.9E-18 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3755934 (gene symbol: ORMDL3) | Whole blood | Meta-analysis | 4170 | cg22144450 | chr17:38080378 | ORMDL3 | NA | 1.8E-17 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg09155575 | chr17:38084037 | ORMDL3 | 0.0013 | 2.6E-17 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3755934 (gene symbol: ORMDL3) | Whole blood | Meta-analysis | 4170 | cg10909506 | chr17:38081995 | ORMDL3 | NA | 4E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.068 | 1.7E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0671068 | 4.1E-16 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg02305874 | chr17:38083354 | ORMDL3 | 0.0005 | 4.4E-16 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg13476672 | chr17:38083406 | ORMDL3 | -9e-05 | 6.7E-16 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg14647739 | chr17:38084012 | ORMDL3 | 0.00061 | 3.8E-15 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3755934 (gene symbol: ORMDL3) | Whole blood | Meta-analysis | 4170 | cg12655416 | chr17:38077870 | ORMDL3 | NA | 4.1E-15 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0063 | 9.1E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.063 | 2.2E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.063 | 3.5E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.062 | 3.8E-14 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg12749226 | chr17:38077703 | ORMDL3 | 0.24 | 5.4E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0620119 | 5.6E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.062 | 6.7E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0613207 | 1.1E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.061 | 1.8E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg08932654 | chr17:38084459 | ORMDL3 | -0.0606415 | 2E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0601469 | 3.1E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg05271360 | chr17:38083955 | ORMDL3 | -6.9e-05 | 5E-13 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Last menstrual period-estimated gestational age | 1068 | cg12655416 | chr17:38077870 | ORMDL3 | -0.00075071 | 7.8E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.058694 | 1.1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.059 | 1.3E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0726121 | 1.4E-12 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg22144450 | chr17:38080378 | ORMDL3 | 2.4 | 2.3E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg22144450 | chr17:38080378 | ORMDL3 | 0.37 | 3.4E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.057 | 4.6E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | sensitivity | 18225 | cg12749226 | chr17:38077703 | ORMDL3 | 0.26 | 7.7E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0563976 | 8.1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0562977 | 8.9E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.055678 | 1.5E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg22144450 | chr17:38080378 | ORMDL3 | 0.36 | 1.7E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg10909506 | chr17:38081995 | ORMDL3 | 0.18 | 3.5E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.055 | 3.8E-11 |
| Kashima K | 33564054 | DNA methylation | gestational age | Cord blood | None | 110 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0053 | 5.8E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg22144450 | chr17:38080378 | ORMDL3 | 0.35 | 6.1E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0657993 | 6.2E-11 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3755903 (gene symbol: GSDMB) | Whole blood | Meta-analysis | 4170 | cg08932654 | chr17:38084459 | ORMDL3 | NA | 1.1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.053 | 1.1E-10 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg10444806 | chr17:38084428 | ORMDL3 | 0.15 | 1.2E-10 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg12655416 | chr17:38077870 | ORMDL3 | -0.037 | 1.2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.053 | 1.2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0529688 | 1.4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.064 | 1.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | 0.053 | 1.8E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0636353 | 1.8E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.052 | 3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.052 | 3.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.052 | 4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0510004 | 6.4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | -0.0560213 | 7E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0601908 | 8.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.051 | 9.1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.063 | 9.8E-10 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg10444806 | chr17:38084428 | ORMDL3 | -0.02 | 1.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0495175 | 2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0490356 | 2.8E-09 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3755862 (gene symbol: IKZF3) | Whole blood | Meta-analysis | 4170 | cg10909506 | chr17:38081995 | ORMDL3 | NA | 3.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg19511844 | chr17:38084119 | ORMDL3 | -0.0487791 | 3.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.058 | 6.5E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg09155575 | chr17:38084037 | ORMDL3 | 0.0037 | 8.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | 0.047 | 8.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | -0.0519024 | 9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 4 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.08 | 1.1E-08 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg04308185 | chr17:38084377 | ORMDL3 | 0.12 | 1.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.047 | 1.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg08932654 | chr17:38084459 | ORMDL3 | -0.0469949 | 1.2E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg09155575 | chr17:38084037 | ORMDL3 | 0.029 | 1.4E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg16638648 | chr17:38083781 | ORMDL3 | 0.0043 | 2E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg22144450 | chr17:38080378 | ORMDL3 | -0.289354 | 2.3E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg26971420 | chr17:38085230 | ORMDL3 | -0.01306 | 2.6E-08 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg12749226 | chr17:38077703 | ORMDL3 | -1.7 | 2.7E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg04145193 | chr17:38083691 | ORMDL3 | 0.0004 | 2.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0559117 | 3.8E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg10909506 | chr17:38081995 | ORMDL3 | 0.15 | 3.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | -0.0453064 | 4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.056 | 4.8E-08 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg04308185 | chr17:38084377 | ORMDL3 | -0.01193 | 5E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg04145193 | chr17:38083691 | ORMDL3 | -0.00032 | 5.4E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg14647739 | chr17:38084012 | ORMDL3 | 0.00051 | 6E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg22144450 | chr17:38080378 | ORMDL3 | -0.00099 | 6.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg02305874 | chr17:38083354 | ORMDL3 | 0.044 | 7.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04145193 | chr17:38083691 | ORMDL3 | 0.044 | 7.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0555639 | 7.4E-08 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Previous week consumption discovery | 5606 | cg12655416 | chr17:38077870 | ORMDL3 | NA | 8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.04428 | 8.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.046 | 1.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg04308185 | chr17:38084377 | ORMDL3 | -0.0437749 | 1.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.044 | 1.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.043544 | 1.3E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg02305874 | chr17:38083354 | ORMDL3 | 0.0021 | 1.4E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg10909506 | chr17:38081995 | ORMDL3 | 0.14 | 1.4E-07 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg12749226 | chr17:38077703 | ORMDL3 | -0.029 | 1.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg19511844 | chr17:38084119 | ORMDL3 | -0.0431442 | 1.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0525193 | 1.8E-07 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg01482279 | chr17:38083788 | ORMDL3 | 0.0072 | 2.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.051961 | 3.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.042 | 3.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0420515 | 3.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.042 | 3.7E-07 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg02305874 | chr17:38083354 | ORMDL3 | 0.0066 | 3.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 2 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.044 | 4.7E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg12655416 | chr17:38077870 | ORMDL3 | 0.16 | 5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.041 | 5.1E-07 |
| Madden RA | 33079621 | DNA methylation | birthweight | Whole blood | birthweight set 2 | 362 | cg04308185 | chr17:38084377 | ORMDL3 | 0.081 | 5.4E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg15942003 | chr17:38084581 | ORMDL3 | -0.13177 | 5.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.041 | 5.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.041 | 5.8E-07 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Ultrasound-estimated gestational age | 1068 | cg12655416 | chr17:38077870 | ORMDL3 | -0.00040454 | 6.1E-07 |
| Jenny van Dongen | 34584077 | DNA methylation | monozygotic twinning | whole blood | None | 5723 | cg08932654 | chr17:38084459 | ORMDL3 | NA | 6.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04308185 | chr17:38084377 | ORMDL3 | -0.0410443 | 6.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 3 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.042 | 7.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg08932654 | chr17:38084459 | ORMDL3 | -0.0408754 | 7.3E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg19511844 | chr17:38084119 | ORMDL3 | -0.123593 | 7.6E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg15942003 | chr17:38084581 | ORMDL3 | -0.129426 | 8.6E-07 |
| Joehanes R | 27651444 | DNA methylation | Current versus never smoking | Whole blood, CD4+ T cells or monocytes | Current vs never smoking | 9389 | cg04308185 | chr17:38084377 | ORMDL3 | -0.0119 | 8.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | 0.041 | 8.6E-07 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg04145193 | chr17:38083691 | ORMDL3 | 0.015 | 8.9E-07 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg14647739 | chr17:38084012 | ORMDL3 | 0.008 | 8.9E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg01482279 | chr17:38083788 | ORMDL3 | 0.0018 | 9E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg18711369 | chr17:38081186 | ORMDL3 | 0.001 | 9.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg04409495 | chr17:38083144 | ORMDL3 | -0.0408957 | 1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.04 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.05 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0400051 | 1.3E-06 |
| Singmann P | 26500701 | DNA methylation | Sex | Whole blood | KORA F4 | 1799 | cg12655416 | chr17:38077870 | ORMDL3 | NA | 1.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | -0.0399177 | 1.3E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg19511844 | chr17:38084119 | ORMDL3 | -0.119734 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg02305874 | chr17:38083354 | ORMDL3 | 0.04 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 4 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0655695 | 1.8E-06 |
| Liu C | 27843151 | DNA methylation | Alcohol consumption per day | Whole blood | European ancestry | 9643 | cg12655416 | chr17:38077870 | ORMDL3 | -0.00011794 | 1.9E-06 |
| Gadd DA | 35945220 | OLFM1 protein levels (SeqId = 5703-26) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg18711369 | chr17:38081186 | ORMDL3 | 0.76 | 2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 3 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0460909 | 2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg08932654 | chr17:38084459 | ORMDL3 | -0.0390055 | 2.3E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg15942003 | chr17:38084581 | ORMDL3 | -0.022 | 2.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.039 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg18711369 | chr17:38081186 | ORMDL3 | 0.04 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0469155 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 4 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.07 | 2.6E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg02152119 | chr17:38083958 | ORMDL3 | -9.3e-05 | 2.6E-06 |
| Jenny van Dongen | 34584077 | DNA methylation | monozygotic twinning | whole blood | None | 5723 | cg10444806 | chr17:38084428 | ORMDL3 | NA | 3.5E-06 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg12655416 | chr17:38077870 | ORMDL3 | -0.00263 | 3.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | 0.038 | 3.8E-06 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg08932654 | chr17:38084459 | ORMDL3 | -0.92 | 4.1E-06 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg02152119 | chr17:38083958 | ORMDL3 | 0.006 | 4.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | -0.0378353 | 4.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.038 | 4.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg04409495 | chr17:38083144 | ORMDL3 | -0.0384739 | 5.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.038 | 5.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.038 | 5.2E-06 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg22144450 | chr17:38080378 | ORMDL3 | -0.0255 | 5.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 4 | 14671 | cg15942003 | chr17:38084581 | ORMDL3 | -0.0422197 | 6E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg18711369 | chr17:38081186 | ORMDL3 | -0.00062 | 6.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 3 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0448875 | 6.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 3 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.046 | 6.7E-06 |
| Gadd DA | 35945220 | CISD2 protein levels (SeqId = 8094-20) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg18711369 | chr17:38081186 | ORMDL3 | 0.71 | 7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg23202472 | chr17:38083134 | ORMDL3 | 0.038 | 7.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | -0.0368893 | 7.8E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg18711369 | chr17:38081186 | ORMDL3 | 0.0042 | 8.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | -0.0366208 | 9.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 4 | 14671 | cg10444806 | chr17:38084428 | ORMDL3 | -0.0374225 | 9.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | 0.037 | 9.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0455729 | 9.7E-06 |
| Madden RA | 33079621 | DNA methylation | birthweight | Whole blood | birthweight set 2 | 362 | cg15942003 | chr17:38084581 | ORMDL3 | 0.055 | 9.7E-06 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Lifetime consumption discovery | 5606 | cg12655416 | chr17:38077870 | ORMDL3 | NA | 9.9E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg08932654 | chr17:38084459 | ORMDL3 | -0.133397 | 9.9E-06 |
| Sikdar S | 31536415 | DNA methylation | Prenatal smoke exposure | Cord blood, whole blood | Inverse varience-weighted fixed-effects meta-analysis | 5648 | cg08932654 | chr17:38084459 | ORMDL3 | -0.009 | 1E-05 |
| Battram T | 23177740 | DNA methylation | Age | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279 | 656 | cg12655416 | chr17:38077870 | ORMDL3 | 0.00038 | 1E-05 |
| Joubert BR | 27040690 | DNA methylation | Maternal smoking in pregnancy | Cord blood | Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts | 5647 | cg08932654 | chr17:38084459 | ORMDL3 | -0.009 | 1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 1 | 14671 | cg19511844 | chr17:38084119 | ORMDL3 | -0.0363706 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.036 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | -0.0362196 | 1.1E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Type 2 Diabetes | Whole blood | Basic model | 17749 | cg22144450 | chr17:38080378 | ORMDL3 | 0.048 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 4 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0592786 | 1.3E-05 |
| Gadd DA | 35945220 | OLFM1 protein levels (SeqId = 5703-26) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg10909506 | chr17:38081995 | ORMDL3 | 0.58 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg08932654 | chr17:38084459 | ORMDL3 | -0.0359832 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.036 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.035979 | 1.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg08932654 | chr17:38084459 | ORMDL3 | -0.128525 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0431853 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 4 | 14671 | cg18711369 | chr17:38081186 | ORMDL3 | 0.038 | 1.4E-05 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Replication | 5704 | cg12655416 | chr17:38077870 | ORMDL3 | NA | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg18711369 | chr17:38081186 | ORMDL3 | 0.037 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | -0.0358246 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.036 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 2 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0448623 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | 0.036 | 1.5E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg02152119 | chr17:38083958 | ORMDL3 | 0.87 | 1.5E-05 |
| Witt S | 32080920 | DNA methylation | alcohol withdrawal recovery | whole blood | discovery | 99 | cg12749226 | chr17:38077703 | ORMDL3 | 1.6 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | 0.036 | 1.6E-05 |
| Jonsson J | 33431374 | DNA methylation | Physical activity and low-energy diet during pregnancy | Cord blood | basic model with smoking adjustment | 208 | cg02152119 | chr17:38083958 | ORMDL3 | NA | 1.7E-05 |
| Battram T | 25282492 | DNA methylation | Age | Fetal liver, adult liver | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE61278. Compared fetal liver tissue to adult liver tissue of different individuals | 110 | cg12655416 | chr17:38077870 | ORMDL3 | -0.384 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg19511844 | chr17:38084119 | ORMDL3 | -0.0354621 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | 0.035 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.044 | 1.8E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg08932654 | chr17:38084459 | ORMDL3 | -0.130142 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 4 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.058 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg04308185 | chr17:38084377 | ORMDL3 | -0.0352838 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg08932654 | chr17:38084459 | ORMDL3 | -0.0357362 | 2E-05 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg08932654 | chr17:38084459 | ORMDL3 | -0.00565 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 3 | 14671 | cg23202472 | chr17:38083134 | ORMDL3 | 0.036 | 2E-05 |
| Liu C | 27843151 | DNA methylation | Alcohol consumption per day | Whole blood | European ancestry | 9643 | cg18711369 | chr17:38081186 | ORMDL3 | -0.00011816 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0351539 | 2.1E-05 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Lifetime consumption discovery | 5606 | cg08932654 | chr17:38084459 | ORMDL3 | NA | 2.3E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg08932654 | chr17:38084459 | ORMDL3 | -0.022 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg15942003 | chr17:38084581 | ORMDL3 | -0.0346504 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg04145193 | chr17:38083691 | ORMDL3 | 0.035 | 2.5E-05 |
| Jonsson J | 33431374 | DNA methylation | Physical activity and low-energy diet during pregnancy | Cord blood | basic model without gestational weight gain adjustment | 208 | cg02152119 | chr17:38083958 | ORMDL3 | NA | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 3 | 14671 | cg15942003 | chr17:38084581 | ORMDL3 | -0.0347766 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | -0.034771 | 2.5E-05 |
| Jonsson J | 33431374 | DNA methylation | Physical activity and low-energy diet during pregnancy | Cord blood | basic model | 208 | cg02152119 | chr17:38083958 | ORMDL3 | NA | 2.6E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg14647739 | chr17:38084012 | ORMDL3 | 0.0016 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 3 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0435173 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0414797 | 2.8E-05 |
| Jonsson J | 33431374 | DNA methylation | Physical activity and low-energy diet during pregnancy | Cord blood | basic model with smoking adjustment and without gestational weight gain adjustment | 208 | cg02152119 | chr17:38083958 | ORMDL3 | NA | 2.9E-05 |
| Gadd DA | 35945220 | SPINK7 protein levels (SeqId = 10974-20) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02979140 | chr17:38083125 | ORMDL3 | -0.5 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | 0.034 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | -0.0344378 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0428069 | 3.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.034 | 3.2E-05 |
| Aghagoli G | 32967004 | cry acoustics factor 1 | DNA methylation | Buccal | None | 335 | cg13476672 | chr17:38083406 | ORMDL3 | -0.002 | 3.3E-05 |
| Gadd DA | 35945220 | GAGE2D protein levels (SeqId = 18273-14) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg18711369 | chr17:38081186 | ORMDL3 | 0.66 | 3.3E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg15942003 | chr17:38084581 | ORMDL3 | -0.85 | 3.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg10444806 | chr17:38084428 | ORMDL3 | -0.0341924 | 3.4E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg19511844 | chr17:38084119 | ORMDL3 | -0.123835 | 3.5E-05 |
| Jonsson J | 33431374 | DNA methylation | Physical activity and low-energy diet during pregnancy | Cord blood | adjustment only for sex and gestational age | 208 | cg02152119 | chr17:38083958 | ORMDL3 | NA | 3.5E-05 |
| Gadd DA | 35945220 | SAA4 protein levels (SeqId = 15516-12) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02979140 | chr17:38083125 | ORMDL3 | -0.498 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0341559 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0421914 | 3.6E-05 |
| Jenny van Dongen | 34584077 | DNA methylation | monozygotic twinning | whole blood | None | 5723 | cg04308185 | chr17:38084377 | ORMDL3 | NA | 3.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg19511844 | chr17:38084119 | ORMDL3 | 0.034 | 3.9E-05 |
| Gadd DA | 35945220 | CEBPA protein levels (SeqId = 18874-66) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg18711369 | chr17:38081186 | ORMDL3 | 0.65 | 4.1E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg08932654 | chr17:38084459 | ORMDL3 | -0.120625 | 4.2E-05 |
| Joubert BR | 27040690 | DNA methylation | Maternal smoking in pregnancy | Cord blood | Sustained maternal smoking in pregnancy effect on newborns | 5647 | cg08932654 | chr17:38084459 | ORMDL3 | -0.008 | 4.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg10909506 | chr17:38081995 | ORMDL3 | 0.034 | 4.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | -0.0337305 | 4.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 4 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0619657 | 4.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg08932654 | chr17:38084459 | ORMDL3 | 0.034 | 4.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg08932654 | chr17:38084459 | ORMDL3 | -0.0335381 | 4.8E-05 |
| Madden RA | 33079621 | DNA methylation | birthweight | Whole blood | birthweight set 2 | 362 | cg08932654 | chr17:38084459 | ORMDL3 | 0.052 | 4.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 2 | 14671 | cg01482279 | chr17:38083788 | ORMDL3 | -0.0344004 | 5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0412605 | 5.1E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg23202472 | chr17:38083134 | ORMDL3 | 0.14 | 5.9E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg05271360 | chr17:38083955 | ORMDL3 | 1.2 | 6.3E-05 |
| Gadd DA | 35945220 | TXNDC11 protein levels (SeqId = 9573-108) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg18711369 | chr17:38081186 | ORMDL3 | 0.64 | 6.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 4 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0567187 | 6.5E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Fully-adjusted model | 14040 | cg22144450 | chr17:38080378 | ORMDL3 | 1.4 | 6.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg04409495 | chr17:38083144 | ORMDL3 | 0.033 | 6.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 3 | 14671 | cg10444806 | chr17:38084428 | ORMDL3 | -0.0326964 | 7.4E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg09155575 | chr17:38084037 | ORMDL3 | -0.0826247 | 7.4E-05 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg08932654 | chr17:38084459 | ORMDL3 | 0.09 | 7.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg12655416 | chr17:38077870 | ORMDL3 | -0.0326841 | 7.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg18711369 | chr17:38081186 | ORMDL3 | -0.0325879 | 7.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01780 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | 0.033 | 8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P13671 | whole blood | OSCA model 1 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0324645 | 8.4E-05 |
| Gadd DA | 35945220 | MCCD1 protein levels (SeqId = 8032-23) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg10909506 | chr17:38081995 | ORMDL3 | 0.52 | 8.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 1 | 14671 | cg22144450 | chr17:38080378 | ORMDL3 | -0.0324135 | 8.6E-05 |
| Gadd DA | 35945220 | MTMR6 protein levels (SeqId = 12536-46) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg18711369 | chr17:38081186 | ORMDL3 | 0.62 | 9E-05 |
| Gadd DA | 35945220 | EXOSC1 protein levels (SeqId = 7930-3) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg18711369 | chr17:38081186 | ORMDL3 | 0.62 | 9.1E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg19511844 | chr17:38084119 | ORMDL3 | -0.115988 | 9.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01714 | whole blood | OSCA model 4 | 14671 | cg12749226 | chr17:38077703 | ORMDL3 | -0.0553278 | 9.7E-05 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg15942003 | chr17:38084581 | ORMDL3 | 0.12 | 9.8E-05 |
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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.
